PAX9_HUMAN - dbPTM
PAX9_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PAX9_HUMAN
UniProt AC P55771
Protein Name Paired box protein Pax-9
Gene Name PAX9
Organism Homo sapiens (Human).
Sequence Length 341
Subcellular Localization Nucleus.
Protein Description Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs..
Protein Sequence MEPAFGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGNLAQQGHYDSYKQHQPTPQPALPYNHIYSYPSPITAAAAKVPTPPGVPAIPGSVAMPRTWPSSHSVTDILGIRSITDQVSDSSPYHSPKVEEWSSLGRNNFPAAAPHAVNGLEKGALEQEAKYGQAPNGLPAVGSFVSASSMAPYPTPAQVSPYMTYSAAPSGYVAGHGWQHAGGTSLSPHNCDIPASLAFKGMQAAREGSHSVTASAL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
60PhosphorylationVSKILARYNETGSIL
HHHHHHHHCCCCCCC		16.2522210691
63PhosphorylationILARYNETGSILPGA
HHHHHCCCCCCCCCC		32.3722210691
65PhosphorylationARYNETGSILPGAIG
HHHCCCCCCCCCCCC		28.5022210691
114UbiquitinationLADGVCDKYNVPSVS
HHCCCCCCCCCCCHH		33.33-
140PhosphorylationNLAQQGHYDSYKQHQ
HHHHCCCCCCCCCCC		17.2627642862
143PhosphorylationQQGHYDSYKQHQPTP
HCCCCCCCCCCCCCC		16.2727642862
144UbiquitinationQGHYDSYKQHQPTPQ
CCCCCCCCCCCCCCC		45.30-
175PhosphorylationAAAAKVPTPPGVPAI
HHHCCCCCCCCCCCC		45.1425159151
194PhosphorylationAMPRTWPSSHSVTDI
CCCCCCCCCCCHHHH		32.0427251275
195PhosphorylationMPRTWPSSHSVTDIL
CCCCCCCCCCHHHHC		18.7227251275
197PhosphorylationRTWPSSHSVTDILGI
CCCCCCCCHHHHCCC		28.7627251275
208PhosphorylationILGIRSITDQVSDSS
HCCCEECCCCCCCCC		22.9429759185
212PhosphorylationRSITDQVSDSSPYHS
EECCCCCCCCCCCCC		26.5825072903
214PhosphorylationITDQVSDSSPYHSPK
CCCCCCCCCCCCCCC		26.2123898821
215PhosphorylationTDQVSDSSPYHSPKV
CCCCCCCCCCCCCCH		34.1721815630
217PhosphorylationQVSDSSPYHSPKVEE
CCCCCCCCCCCCHHH		19.5129759185
219PhosphorylationSDSSPYHSPKVEEWS
CCCCCCCCCCHHHHH		22.1421815630
226PhosphorylationSPKVEEWSSLGRNNF
CCCHHHHHHHCCCCC		20.9723898821
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PAX9_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PAX9_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PAX9_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SSX4_HUMANSSX4physical
20211142
TLE1_HUMANTLE1physical
20211142
TLE2_HUMANTLE2physical
20211142
NR0B2_HUMANNR0B2physical
20211142
FUBP3_HUMANFUBP3physical
20211142
TRIP4_HUMANTRIP4physical
20211142
TF2AY_HUMANGTF2A1Lphysical
20211142
ZN580_HUMANZNF580physical
20211142
ZN440_HUMANZNF440physical
20211142
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PAX9_HUMAN

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Related Literatures of Post-Translational Modification

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