OBE1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: OBE1_ARATH
• UniProt AC: Q9S736
• Protein Name: Protein OBERON 1
• Gene Name: OBE1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 566
• Subcellular Localization: Nucleus .
• Protein Description: Together with OBE2, required for the maintenance and/or establishment of both the shoot and root meristems, probably by controlling the expression of the meristem genes such as WUS, PLT1 and PLT2 and of genes required for auxin responses. Promotes cell meristematic activity via the WUSCHEL-CLAVATA pathway. Involved in the development of the basal pole and in auxin-mediated root and vascular development in the embryo. Confers sensitivity to turnip mosaic virus (TuMV) probably by promoting viral movement and multiplication via interaction with TuMV VPg..
• Protein Sequence: MGTSSGSNLPHQMLPPRQQLQTSLSLVSSDPHLSRSNSGIVRESPAESASSQETWPTSKSIMGRKTDSGKTGPDSHDQHVIRHVSIADKVSLRDIARERLDIVAERMHRLPEEYLEELKNGLKAILEGNGAQPIDEFMFLQKFVQTRSDLTSKTLVRAHRVQLEVLVVINTGIQAFLHPNINLSQSSLIEIFVYKRCRNIACQNELPADGCPCEICANRKGFCNLCMCVICNKFDFAVNTCRWIGCDVCSHWTHTDCAIRDGEISMGVSPKSVSGMGEMLFKCRACNHTSELLGWVKDVFQHCAPNWDRESLMKELDFVSRIFRGSEDTRGRKLFWKCEELMEKIKGGLAEATAAKLILMFFQEIELDSPKSLESGEGGGTIAPQDACNRIAEVVKETLRKMEIVGEEKTRMYKKARMGLEECEREVEEKAKQVAELQMERQKKKQQIEEVERIVRLKQAEAEMFQLKANEAKVEAERLERIVKAKKEKTEEEYASNYLKLRLSEAEAEKEYLFEKIKEQESGGNGGEASQAVMYSKIREMLHGYNASSPRVDPRSNQRNPFRSNP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
36	Phosphorylation	SDPHLSRSNSGIVRE CCCCCCCCCCCCCCC	31.78	23111157
38	Phosphorylation	PHLSRSNSGIVRESP CCCCCCCCCCCCCCC	31.01	28011693
48	Phosphorylation	VRESPAESASSQETW CCCCCCCCCCCCCCC	35.24	30407730
50	Phosphorylation	ESPAESASSQETWPT CCCCCCCCCCCCCCC	41.66	30407730
51	Phosphorylation	SPAESASSQETWPTS CCCCCCCCCCCCCCC	31.58	30407730
54	Phosphorylation	ESASSQETWPTSKSI CCCCCCCCCCCCCHH	29.16	30407730
57	Phosphorylation	SSQETWPTSKSIMGR CCCCCCCCCCHHCCC	40.11	30407730
58	Phosphorylation	SQETWPTSKSIMGRK CCCCCCCCCHHCCCC	21.96	30407730
545	Phosphorylation	IREMLHGYNASSPRV HHHHHCCCCCCCCCC	9.23	25561503
548	Phosphorylation	MLHGYNASSPRVDPR HHCCCCCCCCCCCCC	36.92	25561503
549	Phosphorylation	LHGYNASSPRVDPRS HCCCCCCCCCCCCCC	17.83	30407730

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of OBE1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of OBE1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of OBE1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
P2C80_ARATH	AT5G66720	physical	21798944
PPD5_ARATH	AT5G11450	physical	21798944
MP705_ARATH	MAP70-5	physical	21798944
HEC2_ARATH	HEC2	physical	21798944
CONS_ARATH	CO	physical	21798944
WRK11_ARATH	WRKY11	physical	21798944
OBE1_ARATH	OBE1	physical	22378640
OBE2_ARATH	OBE2	physical	22378640
OBE4_ARATH	AT3G63500	physical	22378640
OBE3_ARATH	AT1G14740	physical	22378640

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.