OBE4_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: OBE4_ARATH
• UniProt AC: Q84TI3
• Protein Name: Protein OBERON 4
• Gene Name: OBE4
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 1162
• Subcellular Localization: Nucleus.
• Protein Sequence: MKRLRSSDDLDFCNDKNVDGEPPNSDRPASSSHRGFFSGNNRDRGEDAAGFSRAFSRRRSNRDLDNHRPDARYHRSESACFSRRAFPKGFRSERERPNRDASVSSWRRFGGPGNDFGVDDRDRRLRDAERDRSLKSPSWSRDSPNELSKFKPLDSRNSRSRSKSLASPTWSKDSGSEQSKSVGNVVKKSEEEVQGKSSTTSSEMEEGELEPEPQPETASGLAHQTKHDCKLPSCSADDHKNARIDRSFQEIGKSAQLDANTESNRELSHVGGNREMETTDSMTDKKSVEDAENVPEHATESMHVSQNNVNDTSTALAIEHDHRDGTITASANKITDTVDEKGDKDEDYKENLHGVKLEETLYPDVPERLEELKEVKGNDGDANKAEVEGPECVEENALANRTPAEYISSVSDSSVHKCKDKGKNSDVPLTHLVGNALFSESKTEDLHDKDKDEKDDNFGGPSIRGFELFSSSPVRRAKKTEQSGVNKHKDEKLLLEPLDLSLSLPDVLLPIGGQDTNQLGSPVRSGSVRSLTDTFCTNSDGFTMSMSFSGSRSFNHNPSCSLSHNIGDNEQSVHSRPIFQGIDWQALSHNDSKYNENTVYQRLMENGNGSVQPRAMKGNLISGQADEEHLRLPDGSSKAANILEKQLSFQKSVDVRSACPRTGSLENGSKFTVEKKTAKDFYSGSNSWITGLEAGGHDFVETVIRYILSDSMPVMTKRFHEMPTRNITSLKENIRQMMLNMDKNVQLGAFQDALQNRTDITLELLTKSHRAQLEILVALKSGRSDFLLLDNSISSSHLAEIFMNMRCKNLSCRVLLPVDECDCRVCSRKDGFCSACMCLVCSNFDMASNTCSWVGCDVCLHWCHTDCGIKESYIRNGINASGAPGMTEMQFHCVACNHPSEMFGFVKEVFLNFAREWKFERFCKELEYVNKIFSSSKDSRGKQLRQAADAMLASLKSKLIGLPEACNRILGFISDCDSSTPAETSAPFIYEQPKPRHERGSPSQDTAWLRSVCSDNPHNQLKRSASVADAFHRERQVEICAVEMELERGSPKEPRFEELESIVRMKQAEAEMFQGRADDARREAEGLKRIAIAKKEKIEEEYNRRMGKLSMEDAQERRRRRYEELEAMQRGQREFYEMKMRMEEEMRGLLTKMEMTKQSLAL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MKRLRSSDDLDFC --CCCCCCCCCCCCC	42.59	23111157
7	Phosphorylation	-MKRLRSSDDLDFCN -CCCCCCCCCCCCCC	28.80	27531888
76	Phosphorylation	PDARYHRSESACFSR CCCCCCCCHHHHHHC	23.69	25561503
78	Phosphorylation	ARYHRSESACFSRRA CCCCCCHHHHHHCCC	31.42	28011693
82	Phosphorylation	RSESACFSRRAFPKG CCHHHHHHCCCCCCC	22.27	25561503
133	Phosphorylation	RDAERDRSLKSPSWS HHHHHHHCCCCCCCC	44.42	25561503
136	Phosphorylation	ERDRSLKSPSWSRDS HHHHCCCCCCCCCCC	29.47	25561503
138	Phosphorylation	DRSLKSPSWSRDSPN HHCCCCCCCCCCCCC	44.78	25561503
140	Phosphorylation	SLKSPSWSRDSPNEL CCCCCCCCCCCCCCH	30.46	25561503
143	Phosphorylation	SPSWSRDSPNELSKF CCCCCCCCCCCHHCC	28.63	24894044
164	Phosphorylation	NSRSRSKSLASPTWS CCCCCCCCCCCCCCC	30.34	25561503
167	Phosphorylation	SRSKSLASPTWSKDS CCCCCCCCCCCCCCC	28.31	30407730
169	Phosphorylation	SKSLASPTWSKDSGS CCCCCCCCCCCCCCC	39.62	25561503
171	Phosphorylation	SLASPTWSKDSGSEQ CCCCCCCCCCCCCCC	29.12	25561503
328	Phosphorylation	DHRDGTITASANKIT ECCCCEEEEECCCCC	17.88	30407730
330	Phosphorylation	RDGTITASANKITDT CCCEEEEECCCCCCC	24.59	30407730
411	Phosphorylation	AEYISSVSDSSVHKC HHHHHCCCHHHHHCC	33.45	30291188
470	Phosphorylation	IRGFELFSSSPVRRA CCCCEEECCCHHHHC	42.40	23776212
471	Phosphorylation	RGFELFSSSPVRRAK CCCEEECCCHHHHCH	31.18	23776212
472	Phosphorylation	GFELFSSSPVRRAKK CCEEECCCHHHHCHH	26.64	23776212
724	Phosphorylation	KRFHEMPTRNITSLK HCHHHCCCCCCHHHH	34.73	24243849
728	Phosphorylation	EMPTRNITSLKENIR HCCCCCCHHHHHHHH	31.40	24243849
729	Phosphorylation	MPTRNITSLKENIRQ CCCCCCHHHHHHHHH	33.38	24243849
1001	Phosphorylation	KPRHERGSPSQDTAW CCCCCCCCCCCCHHH	27.83	29654922
1024	Phosphorylation	PHNQLKRSASVADAF CCHHHHHHHHHHHHH	24.25	27545962
1026	Phosphorylation	NQLKRSASVADAFHR HHHHHHHHHHHHHHH	21.05	23111157

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of OBE4_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of OBE4_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of OBE4_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
OBE1_ARATH	OBE1	physical	22378640
OBE2_ARATH	OBE2	physical	22378640
OBE4_ARATH	AT3G63500	physical	22378640
OBE3_ARATH	AT1G14740	physical	22378640

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks.";
Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.;
Plant Physiol. 150:889-903(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-472, AND MASSSPECTROMETRY.
PubMed: 19376835