NGN1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NGN1_HUMAN
• UniProt AC: Q92886
• Protein Name: Neurogenin-1
• Gene Name: NEUROG1
• Organism: Homo sapiens (Human).
• Sequence Length: 237
• Subcellular Localization: Nucleus .
• Protein Description: Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By similarity)..
• Protein Sequence: MPARLETCISDLDCASSSGSDLSGFLTDEEDCARLQQAASASGPPAPARRGAPNISRASEVPGAQDDEQERRRRRGRTRVRSEALLHSLRRSRRVKANDRERNRMHNLNAALDALRSVLPSFPDDTKLTKIETLRFAYNYIWALAETLRLADQGLPGGGARERLLPPQCVPCLPGPPSPASDAESWGSGAAAASPLSDPSSPAASEDFTYRPGDPVFSFPSLPKDLLHTTPCFIPYH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Oops, there are no PTM records of NGN1_HUMAN !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NGN1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NGN1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NGN1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CBP_HUMAN	CREBBP	genetic	11239394
SMAD1_HUMAN	SMAD1	genetic	11239394
EP300_HUMAN	EP300	genetic	11239394
TRBP2_HUMAN	TARBP2	physical	20211142
MTG8R_HUMAN	CBFA2T2	physical	20211142
ITF2_HUMAN	TCF4	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.