MOXD1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MOXD1_HUMAN
• UniProt AC: Q6UVY6
• Protein Name: DBH-like monooxygenase protein 1
• Gene Name: MOXD1
• Organism: Homo sapiens (Human).
• Sequence Length: 613
• Subcellular Localization: Endoplasmic reticulum membrane; Single-pass type I membrane protein.
• Protein Sequence: MCCWPLLLLWGLLPGTAAGGSGRTYPHRTLLDSEGKYWLGWSQRGSQIAFRLQVRTAGYVGFGFSPTGAMASADIVVGGVAHGRPYLQDYFTNANRELKKDAQQDYHLEYAMENSTHTIIEFTRELHTCDINDKSITDSTVRVIWAYHHEDAGEAGPKYHDSNRGTKSLRLLNPEKTSVLSTALPYFDLVNQDVPIPNKDTTYWCQMFKIPVFQEKHHVIKVEPVIQRGHESLVHHILLYQCSNNFNDSVLESGHECYHPNMPDAFLTCETVIFAWAIGGEGFSYPPHVGLSLGTPLDPHYVLLEVHYDNPTYEEGLIDNSGLRLFYTMDIRKYDAGVIEAGLWVSLFHTIPPGMPEFQSEGHCTLECLEEALEAEKPSGIHVFAVLLHAHLAGRGIRLRHFRKGKEMKLLAYDDDFDFNFQEFQYLKEEQTILPGDNLITECRYNTKDRAEMTWGGLSTRSEMCLSYLLYYPRINLTRCASIPDIMEQLQFIGVKEIYRPVTTWPFIIKSPKQYKNLSFMDAMNKFKWTKKEGLSFNKLVLSLPVNVRCSKTDNAEWSIQGMTALPPDIERPYKAEPLVCGTSSSSSLHRDFSINLLVCLLLLSCTLSTKSL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
36	Ubiquitination	TLLDSEGKYWLGWSQ EEECCCCCEECEEEC	29.24	22817900
36 (in isoform 1)	Ubiquitination	-	29.24	21890473
106	Phosphorylation	KKDAQQDYHLEYAME HHHHHHHHHHHHHHH	12.17	-
110	Phosphorylation	QQDYHLEYAMENSTH HHHHHHHHHHHCCCC	20.01	-
114	N-linked_Glycosylation	HLEYAMENSTHTIIE HHHHHHHCCCCEEEH	38.84	UniProtKB CARBOHYD
247	N-linked_Glycosylation	YQCSNNFNDSVLESG HHCCCCCCHHHHHCC	42.65	UniProtKB CARBOHYD
460	Phosphorylation	MTWGGLSTRSEMCLS CCCCCCHHHHHHHHH	43.17	-
476	N-linked_Glycosylation	LLYYPRINLTRCASI HHHCCCCCCCCCCCC	36.32	UniProtKB CARBOHYD
517	N-linked_Glycosylation	KSPKQYKNLSFMDAM CCHHHHCCCCHHHHH	35.66	UniProtKB CARBOHYD

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MOXD1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MOXD1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MOXD1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
WDR5_HUMAN	WDR5	physical	20581860
GPAA1_HUMAN	GPAA1	physical	28514442
SPCS1_HUMAN	SPCS1	physical	28514442
SPP2B_HUMAN	SPPL2B	physical	28514442
GPC3_HUMAN	GPC3	physical	28514442
PON2_HUMAN	PON2	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.