| UniProt ID | LRC27_HUMAN | |
|---|---|---|
| UniProt AC | Q9C0I9 | |
| Protein Name | Leucine-rich repeat-containing protein 27 | |
| Gene Name | LRRC27 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 530 | |
| Subcellular Localization | ||
| Protein Description | ||
| Protein Sequence | MEGSSSYEVPSVAAADLEEGAGQTRSLPATPSKDVHKGVGGIIFSSSPILDLSESGLCRLEEVFRIPSLQQLHLQRNALCVIPQDFFQLLPNLTWLDLRYNRIKALPSGIGAHQHLKTLLLERNPIKMLPVELGSVTTLKALNLRHCPLEFPPQLVVQKGLVAIQRFLRMWAVEHSLPRNPTSQEAPPVREMTLRDLPSPGLELSGDHASNQGAVNAQDPEGAVMKEKASFLPPVEKPDLSELRKSADSSENWPSEEEIRRFWKLRQEIVEHVKADVLGDQLLTRELPPNLKAALNIEKELPKPRHVFRRKTASSRSILPDLLSPYQMAIRAKRLEESRAAALRELQEKQALMEQQRREKRALQEWRERAQRMRKRKEELSKLLPPRRSMVASKIPSATDLIDNRKVPLNPPGKMKPSKEKSPQASKEMSALQERNLEEKIKQHVLQMREQRRFHGQAPLEEMRKAAEDLEIATELQDEVLKLKLGLTLNKDRRRAALTGNLSLGLPAAQPQNTFFNTKYGESGNVRRYQ | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 32 | Phosphorylation | RSLPATPSKDVHKGV CCCCCCCCCCCCCCC | 36.81 | - | |
| 176 | Phosphorylation | RMWAVEHSLPRNPTS HHHHHHHCCCCCCCC | 26.94 | 22964224 | |
| 182 | Phosphorylation | HSLPRNPTSQEAPPV HCCCCCCCCCCCCCC | 46.74 | - | |
| 193 | Phosphorylation | APPVREMTLRDLPSP CCCCEEEEHHCCCCC | 17.56 | 22210691 | |
| 199 | Phosphorylation | MTLRDLPSPGLELSG EEHHCCCCCCCCCCC | 38.61 | 22210691 | |
| 230 | Phosphorylation | AVMKEKASFLPPVEK CHHHHHHHCCCCCCC | 38.08 | 22210691 | |
| 237 | Acetylation | SFLPPVEKPDLSELR HCCCCCCCCCHHHHH | 44.03 | 7668819 | |
| 326 | Phosphorylation | LPDLLSPYQMAIRAK CHHHCCHHHHHHHHH | 13.93 | - | |
| 358 (in isoform 3) | Phosphorylation | - | 49.83 | - | |
| 372 (in isoform 4) | Phosphorylation | - | 26.36 | - | |
| 520 | Phosphorylation | NTFFNTKYGESGNVR CCCCCCCCCCCCCCC | 24.88 | 23403867 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of LRC27_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of LRC27_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of LRC27_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| HMOX1_HUMAN | HMOX1 | physical | 28514442 | |
| MCM8_HUMAN | MCM8 | physical | 28514442 | |
| SCRIB_HUMAN | SCRIB | physical | 28514442 | |
| IFT52_HUMAN | IFT52 | physical | 28514442 | |
| LRC40_HUMAN | LRRC40 | physical | 28514442 | |
| DPOA2_HUMAN | POLA2 | physical | 28514442 | |
| WDR19_HUMAN | WDR19 | physical | 28514442 | |
| BBS7_HUMAN | BBS7 | physical | 28514442 | |
| PJA1_HUMAN | PJA1 | physical | 28514442 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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