LEG2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LEG2_HUMAN
• UniProt AC: P05162
• Protein Name: Galectin-2
• Gene Name: LGALS2
• Organism: Homo sapiens (Human).
• Sequence Length: 132
• Protein Description: This protein binds beta-galactoside. Its physiological function is not yet known..
• Protein Sequence: MTGELEVKNMDMKPGSTLKITGSIADGTDGFVINLGQGTDKLNLHFNPRFSESTIVCNSLDGSNWGQEQREDHLCFSPGSEVKFTVTFESDKFKVKLPDGHELTFPNRLGHSHLSYLSVRGGFNMSSFKLKE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MTGELEVKN ------CCCEEEEEC	39.09	28102081
16	Phosphorylation	NMDMKPGSTLKITGS CCCCCCCCEEEEEEE	38.81	22210691
23	Phosphorylation	STLKITGSIADGTDG CEEEEEEEEECCCCE	13.12	22210691
63	Phosphorylation	VCNSLDGSNWGQEQR EEECCCCCCCCHHHC	29.13	-
77	Phosphorylation	REDHLCFSPGSEVKF CCCCEEECCCCEEEE	27.62	26657352
80	Phosphorylation	HLCFSPGSEVKFTVT CEEECCCCEEEEEEE	42.47	23312004
112	Phosphorylation	FPNRLGHSHLSYLSV CCCCCCCCCCEEEEE	25.07	28857561
115	Phosphorylation	RLGHSHLSYLSVRGG CCCCCCCEEEEECCC	20.71	24043423
116	Phosphorylation	LGHSHLSYLSVRGGF CCCCCCEEEEECCCC	14.89	24043423
118	Phosphorylation	HSHLSYLSVRGGFNM CCCCEEEEECCCCCC	11.09	28857561
126	Phosphorylation	VRGGFNMSSFKLKE- ECCCCCCCCEECCC-	33.45	28857561
127	Phosphorylation	RGGFNMSSFKLKE-- CCCCCCCCEECCC--	18.68	28857561

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LEG2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LEG2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LEG2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
TNFB_HUMAN	LTA	physical	15129282
TBA1B_HUMAN	TUBA1B	physical	15129282
TBB5_HUMAN	TUBB	physical	15129282
SDCB1_HUMAN	SDCBP	physical	25416956
SDCB2_HUMAN	SDCBP2	physical	25416956
TRI16_HUMAN	TRIM16	physical	27693506

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.