KRBA1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: KRBA1_HUMAN
• UniProt AC: A5PL33
• Protein Name: Protein KRBA1
• Gene Name: KRBA1
• Organism: Homo sapiens (Human).
• Sequence Length: 1030
• Protein Sequence: MRENYETLVSVGTAELLPLSAFLSPSEPGRAVGGGSHADEGQEPAGCGDPQGGQPRHSLHLTALVQLVKEIPEFLFGEVKGAMDSPESESRGASLDGERASPEAAAAREPCPLRGLLSCLPDGPTSQPHLATTPTDSSCSSGPTGDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSPPTHSPSRRKSHRGQERGTSEAGISPGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGTSRLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQENPGAWKRGSGGPGYLLTPPPHPDLGAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPGSSPLQGLENCLKEIPVPVLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESARLGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPPEAAPPVLPASSLQPPCHCGKPLQQELHSLGAALAEKLDRLATALAGLAQEVATMRTQVNRLGRRPQGPGPMGQASWMWTLPRGPRWAHGPGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDLQGLSRGTARRARPLPPDAPPAEPPGLHCSSSQQLLSSTPSCHAAPPAHPLLAHTGGHQSPLPPLVPAALPLQGASPPAASADADVPTSGVAPDGIPERPKEPSSLLGGVQRALQEELWGGEHRDPRWGAH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
80	Ubiquitination	EFLFGEVKGAMDSPE HHHHHCCCCCCCCCC	36.33	-
85	Phosphorylation	EVKGAMDSPESESRG CCCCCCCCCCHHHCC	19.92	28102081
88	Phosphorylation	GAMDSPESESRGASL CCCCCCCHHHCCCCC	44.23	28102081
90	Phosphorylation	MDSPESESRGASLDG CCCCCHHHCCCCCCC	45.34	28102081
94	Phosphorylation	ESESRGASLDGERAS CHHHCCCCCCCCCCC	29.80	28857561
101	Phosphorylation	SLDGERASPEAAAAR CCCCCCCCHHHHHCC	29.51	28857561
144	Phosphorylation	SSCSSGPTGDGVQGS CCCCCCCCCCCCCCC	51.97	27251275
151	Phosphorylation	TGDGVQGSPLPIKTA CCCCCCCCCCCCCCC	13.23	26074081
164	Phosphorylation	TADKPWPTRKEGPGA CCCCCCCCCCCCCCC	50.97	24719451
177	Phosphorylation	GALGGEPSPPTHSPS CCCCCCCCCCCCCCC	38.93	21712546
180	Phosphorylation	GGEPSPPTHSPSRRK CCCCCCCCCCCCCCC	38.07	23403867
182	Phosphorylation	EPSPPTHSPSRRKSH CCCCCCCCCCCCCCC	27.35	21712546
184	Phosphorylation	SPPTHSPSRRKSHRG CCCCCCCCCCCCCCC	47.97	23403867
186	Methylation	PTHSPSRRKSHRGQE CCCCCCCCCCCCCCC	49.52	30760197
190	Methylation	PSRRKSHRGQERGTS CCCCCCCCCCCCCCC	56.43	30760201
196	Phosphorylation	HRGQERGTSEAGISP CCCCCCCCCCCCCCC	29.61	21712546
197	Phosphorylation	RGQERGTSEAGISPG CCCCCCCCCCCCCCC	28.42	29485707
202	Phosphorylation	GTSEAGISPGNSPLQ CCCCCCCCCCCCHHH	26.32	21712546
206	Phosphorylation	AGISPGNSPLQGLIN CCCCCCCCHHHHHHH	32.66	21712546
228	Phosphorylation	PGPRHPETSPSFLPP CCCCCCCCCCCCCCC	50.84	28857561
229	Phosphorylation	GPRHPETSPSFLPPL CCCCCCCCCCCCCCC	19.51	28857561
231	Phosphorylation	RHPETSPSFLPPLPS CCCCCCCCCCCCCCC	38.90	24719451
253	Phosphorylation	RADLGPGSPPWAVKT HHHCCCCCCCCEEEE	30.81	19664994
259	Ubiquitination	GSPPWAVKTEAVSGD CCCCCEEEEEHHCCC	32.66	-
288	Phosphorylation	EAQDRHPSPSGVGNR CHHHCCCCCCCCCCC	26.10	28555341
305	Ubiquitination	QENPGAWKRGSGGPG CCCCCCCCCCCCCCC	46.47	-
308	Phosphorylation	PGAWKRGSGGPGYLL CCCCCCCCCCCCCCC	44.61	28122231
313	Phosphorylation	RGSGGPGYLLTPPPH CCCCCCCCCCCCCCC	11.15	28122231
316	Phosphorylation	GGPGYLLTPPPHPDL CCCCCCCCCCCCCCC	31.02	28122231
330	Phosphorylation	LGAGGLLSVKMENSW CCCCCCEEEEEECCC	25.41	24719451
336	Phosphorylation	LSVKMENSWVQSPPG EEEEEECCCCCCCCC	18.47	26657352
340	Phosphorylation	MENSWVQSPPGPASC EECCCCCCCCCCCCC	24.36	26657352
346	Phosphorylation	QSPPGPASCQPGRQP CCCCCCCCCCCCCCC	19.20	23917254
355	Phosphorylation	QPGRQPLSPSATGDT CCCCCCCCCCCCCCC	24.40	29255136
357	Phosphorylation	GRQPLSPSATGDTRG CCCCCCCCCCCCCCC	34.78	29255136
359	Phosphorylation	QPLSPSATGDTRGVP CCCCCCCCCCCCCCC	39.67	23186163
422	Sumoylation	PGDSRSQKPELQPHR CCCCCCCCCCCCCCC	41.53	-
432	Phosphorylation	LQPHRSHSEEATREP CCCCCCCCHHHHCCC	38.08	28857561
480	Phosphorylation	DWDLDFGSPVGNQGQ CEECCCCCCCCCCCC	19.19	26074081
493	Phosphorylation	GQHPGKGSPPGSSPL CCCCCCCCCCCCCCC	31.26	25850435
497	Phosphorylation	GKGSPPGSSPLQGLE CCCCCCCCCCCHHHH	34.26	25850435
498	Phosphorylation	KGSPPGSSPLQGLEN CCCCCCCCCCHHHHH	35.23	25850435
541	Ubiquitination	PRNWTADKEGLRAEA CCCCCCCCCCCCHHH	51.74	-
558	Methylation	SARLGQGRGEAPTRS HHCCCCCCCCCCCCE	31.71	115481429
570	Phosphorylation	TRSLHLVSPQVFTSS CCEEEECCCHHHCCC	18.90	21712546
675	Phosphorylation	QERDRLPSCKPPVPL CCCCCCCCCCCCCCC	39.09	-
683	Phosphorylation	CKPPVPLSPCPGGTP CCCCCCCCCCCCCCC	20.56	27251275
689	Phosphorylation	LSPCPGGTPAGSSGG CCCCCCCCCCCCCCC	18.84	-
734	Phosphorylation	LEKRPRVSEASRGLE HCCCCCCCHHHHCCC	28.82	-
889	Methylation	RPKPKILRGQGESCR CCCCCCCCCCCCCCC	38.57	115481423
905	Methylation	GDLQGLSRGTARRAR CCCCCCCCCCCCCCC	52.07	115383213

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of KRBA1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of KRBA1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of KRBA1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PLK1_HUMAN	PLK1	physical	21988832
SHCBP_HUMAN	SHCBP1	physical	28514442
P3H2_HUMAN	P3H2	physical	28514442
TBCC1_HUMAN	TBCCD1	physical	28514442
P2R3B_HUMAN	PPP2R3B	physical	28514442
ZMY19_HUMAN	ZMYND19	physical	28514442
IF172_HUMAN	IFT172	physical	28514442
TOM40_HUMAN	TOMM40	physical	28514442
PBX2_HUMAN	PBX2	physical	28514442
TCAL9_HUMAN	WBP5	physical	28514442
TRI27_HUMAN	TRIM27	physical	28514442
JPH1_HUMAN	JPH1	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.