| UniProt ID | HXD12_HUMAN | |
|---|---|---|
| UniProt AC | P35452 | |
| Protein Name | Homeobox protein Hox-D12 | |
| Gene Name | HOXD12 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 270 | |
| Subcellular Localization | Nucleus. | |
| Protein Description | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.. | |
| Protein Sequence | MCERSLYRAGYVGSLLNLQSPDSFYFSNLRPNGGQLAALPPISYPRGALPWAATPASCAPAQPAGATAFGGFSQPYLAGSGPLGLQPPTAKDGPEEQAKFYAPEAAAGPEERGRTRPSFAPESSLAPAVAALKAAKYDYAGVGRATPGSTTLLQGAPCAPGFKDDTKGPLNLNMTVQAAGVASCLRPSLPDGLPWGAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRVVLREQALALY | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 101 | Phosphorylation | PEEQAKFYAPEAAAG HHHHHHHHCCHHHCC | 22.12 | 18083107 | |
| 123 | Phosphorylation | RPSFAPESSLAPAVA CCCCCCHHHHHHHHH | 29.59 | 22210691 | |
| 137 | Phosphorylation | AALKAAKYDYAGVGR HHHHHCCCCCCCCCC | 14.95 | - | |
| 139 | Phosphorylation | LKAAKYDYAGVGRAT HHHCCCCCCCCCCCC | 11.36 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of HXD12_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of HXD12_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of HXD12_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| MAFB_HUMAN | MAFB | physical | 11036080 | |
| MAFK_HUMAN | MAFK | physical | 11036080 | |
| MAFF_HUMAN | MAFF | physical | 11036080 | |
| MAFG_HUMAN | MAFG | physical | 11036080 | |
| TRAF1_HUMAN | TRAF1 | physical | 25416956 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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