| UniProt ID | HS902_ARATH | |
|---|---|---|
| UniProt AC | P55737 | |
| Protein Name | Heat shock protein 90-2 {ECO:0000305} | |
| Gene Name | HSP90-2 {ECO:0000303|PubMed:11599565} | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 699 | |
| Subcellular Localization | Cytoplasm . | |
| Protein Description | Molecular chaperone. Involved in RPM1-mediated resistance. Component of the RPM1/RAR1/SGT1 complex. May stabilize RPM1 and protect it from SGT1-mediated degradation. Associates with RAR1 which may function as co-chaperone. Possesses ATPase activity. [PubMed: 14592967] | |
| Protein Sequence | MADAETFAFQAEINQLLSLIINTFYSNKEIFLRELISNSSDALDKIRFESLTDKSKLDGQPELFIHIIPDKTNNTLTIIDSGIGMTKADLVNNLGTIARSGTKEFMEALAAGADVSMIGQFGVGFYSAYLVADKVVVTTKHNDDEQYVWESQAGGSFTVTRDTSGETLGRGTKMVLYLKEDQLEYLEERRLKDLVKKHSEFISYPISLWIEKTIEKEISDDEEEEEKKDEEGKVEEVDEEKEKEEKKKKKIKEVSHEWDLVNKQKPIWMRKPEEINKEEYAAFYKSLSNDWEEHLAVKHFSVEGQLEFKAILFVPKRAPFDLFDTKKKPNNIKLYVRRVFIMDNCEDIIPEYLGFVKGIVDSEDLPLNISRETLQQNKILKVIRKNLVKKCLELFFEIAENKEDYNKFYEAFSKNLKLGIHEDSQNRTKIAELLRYHSTKSGDELTSLKDYVTRMKEGQNDIFYITGESKKAVENSPFLEKLKKKGIEVLYMVDAIDEYAIGQLKEFEGKKLVSATKEGLKLDETEDEKKKKEELKEKFEGLCKVIKDVLGDKVEKVIVSDRVVDSPCCLVTGEYGWTANMERIMKAQALRDSSMAGYMSSKKTMEINPENSIMDELRKRADADKNDKSVKDLVLLLFETALLTSGFSLDEPNTFGSRIHRMLKLGLSIDDDDAVEADAEMPPLEDDADAEGSKMEEVD | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 6 | Phosphorylation | --MADAETFAFQAEI --CCCHHHHHHHHHH | 23.22 | 25368622 | |
| 213 | Phosphorylation | ISLWIEKTIEKEISD HHHHHHHHHHHHCCC | 22.90 | 23776212 | |
| 219 | Phosphorylation | KTIEKEISDDEEEEE HHHHHHCCCCHHHHH | 39.85 | 30291188 | |
| 255 | Phosphorylation | KKKIKEVSHEWDLVN HHHHHHHHHHHHHHC | 19.44 | 30291188 | |
| 286 | Phosphorylation | EYAAFYKSLSNDWEE HHHHHHHHHCCCHHH | 26.17 | 23776212 | |
| 288 | Phosphorylation | AAFYKSLSNDWEEHL HHHHHHHCCCHHHHH | 39.57 | 30291188 | |
| 476 | Phosphorylation | SKKAVENSPFLEKLK CHHHHHCCHHHHHHH | 11.97 | 19880383 | |
| 595 | Sulfoxidation | QALRDSSMAGYMSSK HHHHCCCCCCCCCCC | 3.77 | 23289948 | |
| 599 | Sulfoxidation | DSSMAGYMSSKKTME CCCCCCCCCCCCCEE | 3.40 | 23289948 | |
| 605 | Sulfoxidation | YMSSKKTMEINPENS CCCCCCCEECCCCCC | 7.17 | 23289948 | |
| 614 | Sulfoxidation | INPENSIMDELRKRA CCCCCCHHHHHHHHH | 3.08 | 23289948 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of HS902_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of HS902_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of HS902_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| TPR1_ARATH | TPR1 | physical | 20856808 | |
| TPR2_ARATH | TPR2 | physical | 20856808 | |
| ADO1_ARATH | ZTL | physical | 21949396 | |
| RAR1_ARATH | PBS2 | physical | 19487680 | |
| SGT1B_ARATH | SGT1B | physical | 19487680 | |
| HS902_ARATH | HSP81-2 | physical | 19487680 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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