GDA1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GDA1_SCHPO
• UniProt AC: Q9UT35
• Protein Name: Guanosine-diphosphatase
• Gene Name: gdp1
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 556
• Subcellular Localization: Golgi apparatus membrane ; Single-pass type II membrane protein .
• Protein Description: After transfer of sugars to endogenous macromolecular acceptors, the enzyme converts nucleoside diphosphates to nucleoside monophosphates which in turn exit the Golgi lumen in a coupled antiporter reaction, allowing entry of additional nucleotide sugar from the cytosol..
• Protein Sequence: MTPTMKSIARRKALLIALSIFAVTFILWNGFPGSSNRPLPSSNDEFHYEDIELPSGYRSEGEVVDLLNPKDELEEPLFSEEPLFPVTTSIPTKTAVSKPKIAPTSAAKDVTFSSSIDSDDCSVAYDNSKPVRQYVLMIDAGSTGSRVHVYQFNNCNPSPKLEEEFFKMIEPGLSSFAGDPEGAAASLDPLLDYAMENVPEEYRRCSPIAVKATAGLRLTGESEAKAILKSVRQHLENDYPFPIVKDGVSILEGSMEGIYAWITINYLLGTLGGKATHSTVAVMDLGGASTQLVFEPRFASDGESLVDGDHKYVLDYNGEQYELYQHSHLGYGLKEARKLIHKFVLNNAEALKESLELLGDSTSIIHPCLHLNASLTHPDSKSEASEVVFVGPSLAHLSLQCRGIAEKALYKDKNCPVRPCSFNGVHQPKFTETFTDSPIYLISYFYDRMISLGMPSTFTIEDMKYLANSVCSGPTYWQDAFSLTDALKELKEEPEWCLDLNYMISLLSVGYEIPNNRQLHTAKKIDNKELGWCLGASLSMLSEQNNGWNCNVKEEI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
206	Phosphorylation	PEEYRRCSPIAVKAT CHHHHCCCHHHEEEC	19.96	29996109
372	N-linked_Glycosylation	IHPCLHLNASLTHPD CHHHHHCCCCCCCCC	19.41	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GDA1_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GDA1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GDA1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
YND1_SCHPO	ynd1	genetic	12686557
RAD26_SCHPO	rad26	genetic	18818364
ARP6_SCHPO	arp6	genetic	18818364
REB1_SCHPO	reb1	genetic	22681890
SSR3_SCHPO	ssr3	genetic	22681890
GPD1_SCHPO	gpd1	genetic	22681890
PFD5_SCHPO	bob1	genetic	22681890
YAJB_SCHPO	SPAC30D11.11	genetic	22681890
YBPC_SCHPO	SPBC16H5.12c	genetic	22681890
HMT2_SCHPO	hmt2	genetic	22681890
LSB5_SCHPO	lsb5	genetic	22681890
YGK4_SCHPO	SPBC725.04	genetic	22681890
YCRA_SCHPO	SPCC285.10c	genetic	22681890
PPID_SCHPO	wis2	genetic	22681890
RAP1_SCHPO	rap1	genetic	22681890
PRZ1_SCHPO	prz1	genetic	22681890

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.