YND1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YND1_SCHPO
• UniProt AC: Q9USP2
• Protein Name: Golgi apyrase {ECO:0000303|PubMed:12686557}
• Gene Name: ynd1 {ECO:0000312|EMBL:CAB57847.1}
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 572
• Subcellular Localization: Golgi apparatus . Membrane ; Single-pass membrane protein .
• Protein Description: Catalyzes the hydrolysis of phosphoanhydride bonds of nucleoside tri- and di-phosphates. Required for Golgi glycosylation and cell wall integrity. Involved in N-mannosylation of proteins in Golgi..
• Protein Sequence: MVRKYGIFIDAGSSGSRLLIYSWDYDTDSSLSDKVKKLPLIETGIGDGGKWSLKVQPGISSFANNPKHVGKKHLKELLDFAAHAIPKDVHKETPVFLSATAGMRLLGVDAQNKILSHACRYIKKNYDFDIPNCSNSIRVIDGKAEGMYGWLATNYLLKTLEEKDTSTVGFLDMGGASVQIAFELPPSQLKNYKDSISTVHIGLQNGQQLEYPLFVTTWLGFGANEAYRRYLGLLIESENGKVGNTLSDPCSLRGRTYDIDGIEFAGTGDLKQCLKLTYNLLNKDKPCSMDPCNFDGISIPPVDFANTEFVGVSEFWYTTNDVFDMGGSYHFPNFYKKVDEYCGTEWETMLSRLYNKELTPSTDENKLEKLCFKASWALNVLHEGFDVPKSNTSSNDAKDGLSVIPAYHSPFTSLEKIERTEVSWTLGQVLLYASNQQLLAKPEYANYYMDPYGKLIASPSKHWMRLFPNKLFFILSFIFCLFFLFSLVLFGYDPKRRQRFKKFLLRLQRRKAPYIMSANGSYEDIADFSDDLEMSSPSKWHGPPIRTTSSHVLADRLSFTASRERTPRSPFP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
547	Phosphorylation	WHGPPIRTTSSHVLA CCCCCCCCCCHHHHH	31.58	25720772
549	Phosphorylation	GPPIRTTSSHVLADR CCCCCCCCHHHHHHH	20.17	29996109
558	Phosphorylation	HVLADRLSFTASRER HHHHHHHCCCCCCCC	22.80	25720772
560	Phosphorylation	LADRLSFTASRERTP HHHHHCCCCCCCCCC	21.98	25720772
562	Phosphorylation	DRLSFTASRERTPRS HHHCCCCCCCCCCCC	31.45	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YND1_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YND1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YND1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TPP1_SCHPO	tpp1	genetic	22681890
GDA1_SCHPO	gda1	genetic	22681890
QCR8_SCHPO	qcr8	genetic	22681890
VPS38_SCHPO	vps38	genetic	22681890
SCS7_SCHPO	scs7	genetic	22681890
CYB51_SCHPO	SPBC29A10.16c	genetic	22681890
PDT1_SCHPO	pdt1	genetic	22681890
SVP26_SCHPO	SPCC1795.10c	genetic	22681890
PRZ1_SCHPO	prz1	genetic	22681890
RF1M_SCHPO	mrf1	genetic	22681890

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.