FX4L6_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FX4L6_HUMAN
• UniProt AC: Q3SYB3
• Protein Name: Forkhead box protein D4-like 6
• Gene Name: FOXD4L6
• Organism: Homo sapiens (Human).
• Sequence Length: 417
• Subcellular Localization: Nucleus .
• Protein Sequence: MNLPRAERLRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEAASQQFLEQSLQPGLQVARWGGVALPREHIEGGGGPSDPSEFGTKFRAPPRSAAASEDARQPAKPPYSYIALITMAILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGNYWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPFPLPAAHAALHNPHPGPLLGAPAPPQPVPGAYPNTAPGRRPYALLHPHPLRYLLLSAPVYAGAPKKAEGAALATPAPFPCCSPHLVLSLGRRARVWRRHREADASLSALRVLCKGSGERVQGLRRVCPRPRGATATCSSDHQACCIPRPLPLCCKCPPPPLLGQFCSNSSSIRRRTAPTAALPPRARCWAGTCRPRRPC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
11	Phosphorylation	PRAERLRSTPQRSLR CHHHHHHCCCCHHHC	49.37	-
130	Phosphorylation	QNPHKRLTLSGICAF HCCCCCCCHHHHHHH	23.94	27762562
139	Phosphorylation	SGICAFISGRFPYYR HHHHHHHHCCCHHHH	19.91	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FX4L6_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FX4L6_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FX4L6_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
LRP1B_HUMAN	LRP1B	physical	26186194
DICER_HUMAN	DICER1	physical	26186194
ZBTB9_HUMAN	ZBTB9	physical	26186194
2ABD_HUMAN	PPP2R2D	physical	26186194
HBAP1_HUMAN	HSPBAP1	physical	26186194
THNS1_HUMAN	THNSL1	physical	26186194
ANR28_HUMAN	ANKRD28	physical	26186194
FBN2_HUMAN	FBN2	physical	26186194
PP2AA_HUMAN	PPP2CA	physical	26186194
FOXD2_HUMAN	FOXD2	physical	26186194
GGPPS_HUMAN	GGPS1	physical	26186194
K0232_HUMAN	KIAA0232	physical	26186194
F192A_HUMAN	FAM192A	physical	26186194
ZN496_HUMAN	ZNF496	physical	26186194
TRBP2_HUMAN	TARBP2	physical	26186194
TRI27_HUMAN	TRIM27	physical	26186194
HBAP1_HUMAN	HSPBAP1	physical	28514442
THNS1_HUMAN	THNSL1	physical	28514442
LRP1B_HUMAN	LRP1B	physical	28514442
ZBTB9_HUMAN	ZBTB9	physical	28514442
2ABD_HUMAN	PPP2R2D	physical	28514442
ZN496_HUMAN	ZNF496	physical	28514442
K0232_HUMAN	KIAA0232	physical	28514442
FBN2_HUMAN	FBN2	physical	28514442
GGPPS_HUMAN	GGPS1	physical	28514442
ANR28_HUMAN	ANKRD28	physical	28514442
TRBP2_HUMAN	TARBP2	physical	28514442
FOXD2_HUMAN	FOXD2	physical	28514442
DICER_HUMAN	DICER1	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.