HBAP1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: HBAP1_HUMAN
• UniProt AC: Q96EW2
• Protein Name: HSPB1-associated protein 1
• Gene Name: HSPBAP1
• Organism: Homo sapiens (Human).
• Sequence Length: 488
• Subcellular Localization: Cytoplasm.
• Protein Description: May play a role in cellular stress response..
• Protein Sequence: MAAGSEATTPVIVAAGAGGEEGEHVKPFKPEKAKEIIMSLQQPAIFCNMVFDWPARHWNAKYLSQVLHGKQIRFRMGMKSMSTVPQFETTCNYVEATLEEFLTWNCDQSSISGPFRDYDHSKFWAYADYKYFVSLFEDKTDLFQDVKWSDFGFPGRNGQESTLWIGSLGAHTPCHLDSYGCNLVFQVQGRKRWHLFPPEDTPFLYPTRIPYEESSVFSKINVVNPDLKRFPQFRKAQRHAVTLSPGQVLFVPRHWWHYVESIDPVTVSINSWIELEEDHLARVEEAITRMLVCALKTAENPQNTRAWLNPTEVEETSHAVNCCYLNAAVSAFFDRCRTSEVVEIQALRTDGEHMKKEELNVCNHMEVGQTGSQNLTTGTDKPEAASPFGPDLVPVAQRSEEPPSERGGIFGSDGKDFVDKDGEHFGKLHCAKRQQIMSNSENAIEEQIASNTTTTPQTFISTDDLLDCLVNPQVTRIVAQLLIQGRSL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Phosphorylation	MAAGSEATTPVIVAA CCCCCCCCCCEEEEC	27.81	25627689
9	Phosphorylation	AAGSEATTPVIVAAG CCCCCCCCCEEEECC	23.70	25627689
26	Ubiquitination	GEEGEHVKPFKPEKA CCCCCCCCCCCHHHH	46.79	-
147	Ubiquitination	TDLFQDVKWSDFGFP CCHHCCCCHHHCCCC	49.63	21906983
147 (in isoform 3)	Ubiquitination	-	49.63	21906983
147 (in isoform 2)	Ubiquitination	-	49.63	21906983
147 (in isoform 1)	Ubiquitination	-	49.63	21906983
219	Ubiquitination	EESSVFSKINVVNPD CCCHHHHHCCCCCCC	27.17	21906983
219 (in isoform 3)	Ubiquitination	-	27.17	21906983
219 (in isoform 1)	Ubiquitination	-	27.17	21906983
228 (in isoform 3)	Ubiquitination	-	60.41	21906983
228 (in isoform 1)	Ubiquitination	-	60.41	21906983
228	Ubiquitination	NVVNPDLKRFPQFRK CCCCCCHHCCHHHHH	60.41	2190698
274 (in isoform 3)	Phosphorylation	-	43.82	22210691
275 (in isoform 3)	Phosphorylation	-	6.86	22210691
296	Ubiquitination	RMLVCALKTAENPQN HHHHHHHHCCCCCCC	27.45	-
427	Ubiquitination	KDGEHFGKLHCAKRQ CCCCEECHHHHHHHH	33.83	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of HBAP1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of HBAP1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of HBAP1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PTN_HUMAN	PTN	physical	16169070
NUTM1_HUMAN	NUTM1	physical	25416956
NCALD_HUMAN	NCALD	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.