NCALD_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NCALD_HUMAN
• UniProt AC: P61601
• Protein Name: Neurocalcin-delta
• Gene Name: NCALD
• Organism: Homo sapiens (Human).
• Sequence Length: 193
• Protein Description: May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions..
• Protein Sequence: MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQCDPSSAGQF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Myristoylation	------MGKQNSKLR ------CCCCCCCCC	40.01	-
50	Ubiquitination	LSMEEFKKIYGNFFP CCHHHHHHHHCCCCC	46.62	21890473
102	"N6,N6-dimethyllysine"	GKLEQKLKWAFSMYD CHHHHHHHHHCCEEE	43.44	-
102	Methylation	GKLEQKLKWAFSMYD CHHHHHHHHHCCEEE	43.44	-
106	Phosphorylation	QKLKWAFSMYDLDGN HHHHHHCCEEECCCC	14.53	27251275
129	Phosphorylation	LEIVQAIYKMVSSVM HHHHHHHHHHHHHHH	8.96	-
137	Ubiquitination	KMVSSVMKMPEDEST HHHHHHHCCCCCCCC	49.50	21890473
143	Phosphorylation	MKMPEDESTPEKRTE HCCCCCCCCHHHHHH	62.68	29255136
144	Phosphorylation	KMPEDESTPEKRTEK CCCCCCCCHHHHHHH	33.16	29255136
174	Ubiquitination	EEFIRGAKSDPSIVR HHHHHHCCCCHHHHH	59.21	-
175	Phosphorylation	EFIRGAKSDPSIVRL HHHHHCCCCHHHHHH	54.97	26657352
178	Phosphorylation	RGAKSDPSIVRLLQC HHCCCCHHHHHHHCC	38.41	27251275

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NCALD_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NCALD_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NCALD_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DTX2_HUMAN	DTX2	physical	16189514
DTX2_HUMAN	DTX2	physical	25416956
C1QT2_HUMAN	C1QTNF2	physical	25416956

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.