FA43A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FA43A_HUMAN
• UniProt AC: Q8N2R8
• Protein Name: Protein FAM43A
• Gene Name: FAM43A
• Organism: Homo sapiens (Human).
• Sequence Length: 423
• Protein Sequence: MLPWKKHKFELLAEAPPRQASKPKGYAVSLHYSALSSLARACPEGALSRVGSMFRSKRKKLHITSEDPTYTVLYLGNATTIQARGDGCTDLAVGKIWSKSEAGRQGTKMKLTVSAQGIRMVHAEERALRRPGHLYLLHRVTYCVADARLPKVFAWVYRHELKHKAVMLRCHAVLVSKPEKAQAMALLLYQTSANALAEFKRLKRRDDARHQQQELVGAHTIPLVPLRKLLLHGPCCYKPPVERSRSAPKLGSITEDLLGEQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAEAQRALVVAMHFECGDLLDTLENGRGEALGGGGGSLGPGAGPPPLLLGSASDMKAELSQLISDLGELSFGNDVRTLQADLRVTRLLSGDSTGSESSIEGGGPDATSATAGDSSRQADGASADEPHSG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
21	Phosphorylation	EAPPRQASKPKGYAV CCCCCCCCCCCCEEE	40.95	25072903
26	Phosphorylation	QASKPKGYAVSLHYS CCCCCCCEEEEHHHH	15.23	25072903
29	Phosphorylation	KPKGYAVSLHYSALS CCCCEEEEHHHHHHH	10.97	25072903
32	Phosphorylation	GYAVSLHYSALSSLA CEEEEHHHHHHHHHH	10.84	25072903
33	Phosphorylation	YAVSLHYSALSSLAR EEEEHHHHHHHHHHH	16.40	25072903
36	Phosphorylation	SLHYSALSSLARACP EHHHHHHHHHHHHCC	24.03	25072903
37	Phosphorylation	LHYSALSSLARACPE HHHHHHHHHHHHCCH	27.22	25072903
112	Phosphorylation	QGTKMKLTVSAQGIR CCCEEEEEEEEHHEE	13.59	28464451
114	Phosphorylation	TKMKLTVSAQGIRMV CEEEEEEEEHHEEEE	15.05	-
157	Phosphorylation	PKVFAWVYRHELKHK HHHHHHHHHHHHHHH	8.78	28152594
379	Phosphorylation	LQADLRVTRLLSGDS HHHCCEEEEECCCCC	14.79	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FA43A_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FA43A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FA43A_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
AKA11_HUMAN	AKAP11	physical	26186194
WAP53_HUMAN	WRAP53	physical	26186194
2AAB_HUMAN	PPP2R1B	physical	26186194
2A5G_HUMAN	PPP2R5C	physical	26186194
2A5D_HUMAN	PPP2R5D	physical	26186194
2A5A_HUMAN	PPP2R5A	physical	26186194
2A5B_HUMAN	PPP2R5B	physical	26186194
2A5E_HUMAN	PPP2R5E	physical	26186194
TBL3_HUMAN	TBL3	physical	26186194
CBWD1_HUMAN	CBWD1	physical	26186194
SNX6_HUMAN	SNX6	physical	26186194
2A5E_HUMAN	PPP2R5E	physical	28514442
2A5A_HUMAN	PPP2R5A	physical	28514442
2A5B_HUMAN	PPP2R5B	physical	28514442
2A5D_HUMAN	PPP2R5D	physical	28514442
2A5G_HUMAN	PPP2R5C	physical	28514442
WAP53_HUMAN	WRAP53	physical	28514442
2AAB_HUMAN	PPP2R1B	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.