DTBP1_DROME - dbPTM
DTBP1_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID DTBP1_DROME
UniProt AC Q9VVT5
Protein Name Dysbindin protein homolog
Gene Name Dysb {ECO:0000312|FlyBase:FBgn0036819}
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 288
Subcellular Localization
Protein Description Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in pigment granule biogenesis..
Protein Sequence MFGNLKKKLSSAIQEGLVISENLQQQYRQRVSSGNSGSSQASGITTPISPLGLNESLSSSRSSSLSLSAPFQLTDGVPSHLNVAAGCSLLAKYEDDWQQIHGANEKNAEKAAQIANQISGIQDQASHQHRIMSELNSSLAGIPTLIAQLQNSSQVLNSLEEMGKQLEIELEKLEDLREECELQEFILEQQFQLSRHKQKKLNELEQYRQQIAQKHQSKIKDQEQTLLKLQRERQAVFDDAFREDMEEYKQRGQLTKIQTTSNKLALEEVVLEANEVETKDALEQFLNG
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
10PhosphorylationGNLKKKLSSAIQEGL
CCHHHHHHHHHHHCC
21082442
32PhosphorylationQQYRQRVSSGNSGSS
HHHHHHHHCCCCCCC
21082442
39PhosphorylationSSGNSGSSQASGITT
HCCCCCCCCCCCCCC
21082442
42PhosphorylationNSGSSQASGITTPIS
CCCCCCCCCCCCCCC
21082442
63PhosphorylationSLSSSRSSSLSLSAP
CCCCCCCCCCCEECC
21082442
64PhosphorylationLSSSRSSSLSLSAPF
CCCCCCCCCCEECCE
21082442

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of DTBP1_DROME !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of DTBP1_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of DTBP1_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CCD22_DROMECG9951physical
14605208
SPC25_DROMESpc25physical
14605208
NUP54_DROMENup54physical
14605208
NSF1_DROMEcomtgenetic
25972187
BL1S1_DROMEBlos1physical
25568125
SNAPN_DROMESnapinphysical
25568125
BL1S4_DROMEBlos4physical
25568125
BL1S2_DROMEBlos2physical
25568125
BL1S6_DROMEPallidinphysical
25568125
BL1S5_DROMEMutedphysical
25568125
BL1S3_DROMEBlos3physical
25568125

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of DTBP1_DROME

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Related Literatures of Post-Translational Modification

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