| UniProt ID | DMC1_HUMAN | |
|---|---|---|
| UniProt AC | Q14565 | |
| Protein Name | Meiotic recombination protein DMC1/LIM15 homolog | |
| Gene Name | DMC1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 340 | |
| Subcellular Localization | Nucleus . Chromosome. | |
| Protein Description | May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.. | |
| Protein Sequence | MKEDQVVAEEPGFQDEEESLFQDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNVDHDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAKE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 251 | Phosphorylation | QKLAQMLSRLQKISE HHHHHHHHHHHHHHH | 26.13 | 23403867 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of DMC1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of DMC1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of DMC1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| RAD51_HUMAN | RAD51 | physical | 10562567 | |
| DNJA3_HUMAN | DNAJA3 | physical | 11005857 | |
| BRCA2_HUMAN | BRCA2 | physical | 17541404 | |
| DMC1_HUMAN | DMC1 | physical | 25416956 | |
| GORS2_HUMAN | GORASP2 | physical | 25416956 | |
| NIF3L_HUMAN | NIF3L1 | physical | 25416956 | |
| KCD17_HUMAN | KCTD17 | physical | 25416956 | |
| POTEF_HUMAN | POTEF | physical | 26186194 | |
| ACTS_HUMAN | ACTA1 | physical | 26186194 | |
| RAD51_HUMAN | RAD51 | physical | 26186194 | |
| RFWD2_HUMAN | RFWD2 | physical | 26186194 | |
| SVIP_HUMAN | SVIP | physical | 26186194 | |
| ACTS_HUMAN | ACTA1 | physical | 28514442 | |
| RAD51_HUMAN | RAD51 | physical | 28514442 | |
| POTEF_HUMAN | POTEF | physical | 28514442 | |
| SVIP_HUMAN | SVIP | physical | 28514442 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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