dbPTM

DAPKR_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	DAPKR_DROME
UniProt AC	Q0KHT7
Protein Name	Death-associated protein kinase related
Gene Name	Drak
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	674
Subcellular Localization
Protein Description
Protein Sequence	MFTEKGIFPIGDGLLDVDADRLKGLLVSCPDINEIYEVEQTPFARGKFAAVRRAIHKNTGSHFAAKFLKRRRRAQSSDKEIKHEIAVLMLCEGEDNIVNLNAVHETRSDTALLLELATGGELQTILDNEECLTEAQARHCMREVLKALKFLHDRSIAHLDLKPQNILLAGERIEDGLKLCDFGISRVVCEGINVREMAGTPDYVAPEVLQYEPLSLLTDIWSVGVLTYVLLSGFSPFGGDTKQETFLNISQCALTFPDNLFGGVSPVAIDFIRRALRIKPNDRMNATGCLDHIWLKDDCSLDRQIYLQPQSDAEEEEEEDVDDDVEDEEEEEQVEEEEEETQNVEEPTTEAPQQQQQPVQQHQLAKSGQIHSKPTHNGHHRANSGGSISKIPIATSKLQSTPSSETTTAIHTLTSNSNGHVHKPTQIVTPTRRASDSDKENTYTATFVKKPVATIQLGSSNGIEDATVVATLTLFPDAPTTPKVIRKTPTGESNGSATSVKALVKKFQLEDSSGSAVARRSGGAVTSSSGLHSPTTTSVRLNSIRRASEPLTTVYKKQTSQNGCSSTSNPSSSPGSSPTTSGSTATLLIHSQRLGNSTAPASHCVAVPATATATSSASSSNSSSGKSTSAAHHLHHHHMHHHHHHHHHHVVIAAKNAAAVAATNNLSLDQGIIC

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
384	Phosphorylation	NGHHRANSGGSISKI CCCCCCCCCCCCCCC	22817900
387	Phosphorylation	HRANSGGSISKIPIA CCCCCCCCCCCCCCC	22817900
435	Phosphorylation	VTPTRRASDSDKENT ECCCCCCCCCCCCCE	22817900
437	Phosphorylation	PTRRASDSDKENTYT CCCCCCCCCCCCEEE	22817900
521	Phosphorylation	GSAVARRSGGAVTSS CCCEEHHCCCCEECC	22817900
548	Phosphorylation	LNSIRRASEPLTTVY HHHHHHCCCCCEEEE	19429919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of DAPKR_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of DAPKR_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of DAPKR_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SQH_DROME	sqh	genetic	20573980
RHO1_DROME	Rho1	genetic	20573980
MYSN_DROME	zip	genetic	20573980
STUB_DROME	Sb	genetic	20573980
PP1B_DROME	flw	genetic	20573980

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of DAPKR_DROME

Related Literatures of Post-Translational Modification