COX5A_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: COX5A_DROME
• UniProt AC: Q94514
• Protein Name: Cytochrome c oxidase subunit 5A, mitochondrial
• Gene Name: COX5A {ECO:0000312|FlyBase:FBgn0019624}
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 149
• Subcellular Localization: Mitochondrion inner membrane.
• Protein Description: This is the heme A-containing chain of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport..
• Protein Sequence: MLSITARNLASALRSSLVGTSSRVAAVRCLHGTEESAEEFDKRYEKYFSREGIDGWEIRKGMNDLLGMDLVPSPKIIEAGLRASRRVNDIALAIRWLEGCKDKCGDQKATLYPYLLEKITPTLQELGIPTIEELGYDKPELALKSVYDA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
46	Acetylation	EFDKRYEKYFSREGI HHHHHHHHHHHCCCC	42.53	21791702

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of COX5A_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of COX5A_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of COX5A_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RS28_DROME	RpS28b	physical	14605208
ACT1_DROME	Act5C	physical	14605208
RLA1_DROME	RpLP1	physical	14605208
RL9_DROME	RpL9	physical	14605208
ATPK_DROME	CG4692	physical	22036573
CUL1_DROME	Cul1	genetic	20176921
FBXW7_DROME	ago	genetic	20176921
PSB1_DROME	Prosbeta6	genetic	20176921

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.