CHCH1_HUMAN - dbPTM
CHCH1_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CHCH1_HUMAN
UniProt AC Q96BP2
Protein Name Coiled-coil-helix-coiled-coil-helix domain-containing protein 1
Gene Name CHCHD1
Organism Homo sapiens (Human).
Sequence Length 118
Subcellular Localization Mitochondrion . Nucleus .
Protein Description
Protein Sequence MATPSLRGRLARFGNPRKPVLKPNKPLILANRVGERRREKGEATCITEMSVMMACWKQNEFRDDACRKEIQGFLDCAARAQEARKMRSIQETLGESGSLLPNKLNKLLQRFPNKPYLS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
3Phosphorylation-----MATPSLRGRL
-----CCCHHHHHHH
16.4724719451
5Phosphorylation---MATPSLRGRLAR
---CCCHHHHHHHHH
26.7524719451
7Methylation-MATPSLRGRLARFG
-CCCHHHHHHHHHCC
32.30-
68UbiquitinationFRDDACRKEIQGFLD
CCCHHHHHHHHHHHH
60.0829967540
103UbiquitinationSGSLLPNKLNKLLQR
CCCCCCHHHHHHHHH
52.0422817900
106UbiquitinationLLPNKLNKLLQRFPN
CCCHHHHHHHHHCCC
62.1022817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CHCH1_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CHCH1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CHCH1_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CHCH1_HUMANCHCHD1physical
27499296
PPM1K_HUMANPPM1Kphysical
27499296
NRDC_HUMANNRD1physical
27499296
IDE_HUMANIDEphysical
27499296
MIA40_HUMANCHCHD4physical
27499296
MPPA_HUMANPMPCAphysical
27499296
CBY1_HUMANCBY1physical
27173435

Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CHCH1_HUMAN

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Related Literatures of Post-Translational Modification

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