CH60B_DROME - dbPTM
CH60B_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CH60B_DROME
UniProt AC Q9VPS5
Protein Name 60 kDa heat shock protein homolog 1, mitochondrial
Gene Name Hsp60B
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 648
Subcellular Localization Mitochondrion matrix.
Protein Description Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions..
Protein Sequence MFRSCVPKAITSSRCFARMYSKDVRFGSGVRAMMIRGVDILADAVAVTMGPKGRSVIVERPWTSPKITKDGFTVARSIALKDQHMNLGAKLVQDVADNTNESAGDGTTTATVLARAIAKEGFNQITMGANPVEIRRGVMLAVDVVKDKLKEMSKAVETREEIQQVATLSANGDTEIGRLIGEATDKVGPRGTITVKDGKRLKDELNIIQGLRFDNGYVSPFFVNSSKGSKVEFANALVMISLKKITGLSQIVKGLEQSLRQRRPLIIIAEDISGEALNALVLNKLRLGLQVCAVKSPSYGHHRKELIGDISAATGATIFGDDINYSKMEEAKLEDLGQVGEAVISKDSTMLLQGKPKTGLLEMRIQQIQDELAEKQIKPEQRDRLRQRLSALTKGVAVLHIGGGSEVEVNEKKDRVVDALNATRAAIEEGIVPGGGTAFLRCIPYLQELKTESADLQKGVDIVCNALRMPCQTIAQNAGVDGPMVVAKVLNGSEDYGYDAMGDEYCRLVEKGIIDPTKVLRTAITDAAGVASLLSTTEVVITDSRNDDLLSKLSGAGGGMDDGLDMNMGGLEELAALSGLGGMGGMGGMGGMGGMGGMGGGFGGMGAGGGMSASASNDGPTAEEMNEMVKAIPGMEQVEVRDIDSGMM
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
148AcetylationAVDVVKDKLKEMSKA
HHHHHHHHHHHHHHH
56.6021791702
150AcetylationDVVKDKLKEMSKAVE
HHHHHHHHHHHHHHH
58.0521791702
405PhosphorylationVLHIGGGSEVEVNEK
EEEECCCCCEEECCC
41.5722668510

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CH60B_DROME !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CH60B_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CH60B_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PREP_DROMECG3107physical
14605208
JOSL_DROMECG3781physical
14605208
FLNA_DROMEcherphysical
14605208
CDK1_DROMEcdc2physical
14605208
CSKP_DROMECASKphysical
14605208
CSN6_DROMECSN6physical
14605208
JMJD4_DROMECG7200physical
14605208
CTBP_DROMECtBPphysical
14605208
G3P2_DROMEGapdh2physical
14605208
MUT7_DROMENbrphysical
14605208

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CH60B_DROME

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Related Literatures of Post-Translational Modification

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