dbPTM

PREP_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PREP_DROME
UniProt AC	Q9V9E3
Protein Name	Presequence protease, mitochondrial
Gene Name	CG3107
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	1034
Subcellular Localization	Mitochondrion.
Protein Description	ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides (By similarity)..
Protein Sequence	MLKGGMLSRWKMWSPQYKILRNHLINFKSVSTYKNISGVNTKQPKSPRQFGCMPHVTKKRKYKYEEGKTYHGFQCERVEHISEFELTSYTFRYERTGTELWHIDRNDSNNVFSINFRTTPFDSTGLPHILEHLSLCGSQKYPVRDPFFKMLNRSVATFMNAMTGPDYTIYPFSTMNEIDFRNLQHIYLDAVFRPNLAYFDFLQEGWRLENKDIFDKQSKLVIKGVVYNEMKGAFSENAQVFSQNLLNNIFPDHTYRHVSGGNPLEIPKLAYNDLVEFHKKYYHPSNARIYSYGLFDASKTLALLDEEYLSDQSWVDNSYSLIRQQERWTQPRLVHISSRLDNMGTTIDRQNQIAIALLMCDATNIQESFELHVLSEVLIRGPNSPFYKNLIEPNFSGGYNQTTGYSSDTKDTTFVVGLQDLRVEDFKKCIEIFDKTIINSMNDGFDSQHVESVLHNLELSLKHQNPNFGNTLLFNSTALWNHDGDVVSNLRVSDMISGLRESISQNKKYFQEKIEKYFANNNHRLTLTMSPDEAYEDKFKQAELELVEQKVKLLDEVKIEKIYERGLILDSYQKAESNTDLLPCLTMNDVRDPPKWPKLFIQNVQNVRTQICKVPTNEITYFKCMFNITGLSHEETQLMPLFCNVISAMGTTNYNYREFDKHILLKTGGFDFKLHLIEDVRDSKSYSLSVMINTHALNNNVPEMFALCQELIKNVRFDDSERLKMLIENYISYISVGVASSGHLYAMLGATSQVCDAGKLKSLLYGVDHIDFMKNFVHSTSTVDICDKLSTIASKVFNKDNMRGAINTTQSYEPSAISNYEKFLESLPTFGKTQTSRNIHYLDPSCQQYVMNIPVNYCAKALFTVPYLHQDHPTLRVLAKLLSAKYLLPVIREKNGAYGAGAKISSDGIFSFYSYRDPNSTKTLNAFDETYKWLRANQNVIDQQSLFESKLGVLQQLDTPIAPGNIGIDYFLYEVSQEDFESYRSRMLSVTIDDLQCAIENYFGKESMHYGKCILGPVNANLELETSHKWIINN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
558	Acetylation	VKLLDEVKIEKIYER HHHHHHHHHHHHHHC	43.00	21791702
561	Acetylation	LDEVKIEKIYERGLI HHHHHHHHHHHCCCC	54.80	21791702
922	Acetylation	YRDPNSTKTLNAFDE ECCCCCCCEEHHHHH	51.33	21791702

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PREP_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PREP_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PREP_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PREP_DROME

Related Literatures of Post-Translational Modification