| UniProt ID | CATIN_DROME | |
|---|---|---|
| UniProt AC | Q9VR99 | |
| Protein Name | Cactin | |
| Gene Name | cactin | |
| Organism | Drosophila melanogaster (Fruit fly). | |
| Sequence Length | 720 | |
| Subcellular Localization | ||
| Protein Description | Plays a role during early embryonic development. Involved in the dorsal-ventral embryonic patterning. Probably acts as a negative regulator of the NF-kappa-B (Rel) signaling pathway.. | |
| Protein Sequence | MPKEKSKHRHRSRSRERRDHRSPDPRSSRNRDRDREREREKDRDHRDHRDKERDQRREREKDKSRDKKREHKSRRRRSSSSSSSPSSSTSSSVPGAPRSPLVKSPMKLLQTLEARRLVEQKDRQRKKEELKAHETPEEKRARRLREKQAKEQRRRERMGWDNEYQTYSNEDNPFGDSNLTSTFHWGKKLEVEGLSNLSTKTVEVLSLQKQLENRRELEKVKKRRQERELERQVREDDLMMQQRAKEAVQFREWQRQEDQFHLEQARLRSEIRIRDGRAKPIDLLAQYVAAGNEPLEECLEMQMHEPYVLLNGLPVEELEDLLVDIKVYEELEQGKHIDFWNDMITIVQDELQRQQKLEAENSSLNQRRDGIHQAVVKDVADIFRGKNAQQLEEMRHRIEAKISGRADGVDISYWESLLSQLKAHMARARLRDRHQALLREKLSLLKRENDNETLQEKVAPQVKEEEMETQDAEDPEVEEGSPEDEEDPLNELRKTVRLYQAGNYSPRYIREEDFTGRRAQNEDVDEPEAEGLLYEEEDDERRTQRQRLLILHPERVDNNQLTPQELRMRNEAKQGMQGDEAEFSVETTLDAVPQLATDKYRPRKPRYFNRVHTGFEWNKYNQTHYDMDNPPPKIVQGYKFNIFYPDLMDKSQTPQYFLTPCADNGDFAVLRFHTGPPYEDIAFKIVNREWEFSYKRGFRCQFHNNIFQLWFHFKRYRYRR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 22 | Phosphorylation | RERRDHRSPDPRSSR HHHCCCCCCCCCCCC | 27626673 | ||
| 99 | Phosphorylation | SVPGAPRSPLVKSPM CCCCCCCCCCCCCHH | 25749252 | ||
| 104 | Phosphorylation | PRSPLVKSPMKLLQT CCCCCCCCHHHHHHH | 25749252 | ||
| 195 | Phosphorylation | KLEVEGLSNLSTKTV EEEEECCCCCCCCHH | 19429919 | ||
| 198 | Phosphorylation | VEGLSNLSTKTVEVL EECCCCCCCCHHHHH | 19429919 | ||
| 199 | Phosphorylation | EGLSNLSTKTVEVLS ECCCCCCCCHHHHHH | 19429919 | ||
| 469 | Phosphorylation | VKEEEMETQDAEDPE HCHHHHHCCCCCCCC | 23607784 | ||
| 481 | Phosphorylation | DPEVEEGSPEDEEDP CCCCCCCCCCCCCCH | 19429919 | ||
| 505 | Phosphorylation | LYQAGNYSPRYIREE HHHCCCCCCCCCCHH | 19429919 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CATIN_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CATIN_DROME !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CATIN_DROME !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| U428_DROME | CG16865 | physical | 14605208 | |
| EWG_DROME | ewg | physical | 14605208 | |
| CRN_DROME | crn | physical | 14605208 | |
| RL23_DROME | RpL23 | physical | 14605208 | |
| ACOX1_DROME | CG5009 | physical | 14605208 | |
| SRP68_DROME | Srp68 | physical | 14605208 | |
| RSMB_DROME | SmB | physical | 14605208 | |
| MYSP1_DROME | Prm | physical | 14605208 | |
| MYSP2_DROME | Prm | physical | 14605208 | |
| RT26_DROME | mRpS26 | physical | 14605208 | |
| RM24_DROME | mRpL24 | physical | 14605208 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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