dbPTM

CABIN_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CABIN_HUMAN
UniProt AC	Q9Y6J0
Protein Name	Calcineurin-binding protein cabin-1
Gene Name	CABIN1
Organism	Homo sapiens (Human).
Sequence Length	2220
Subcellular Localization	Nucleus .
Protein Description	May be required for replication-independent chromatin assembly. May serve as a negative regulator of T-cell receptor (TCR) signaling via inhibition of calcineurin. Inhibition of activated calcineurin is dependent on both PKC and calcium signals. Acts as a negative regulator of p53/TP53 by keeping p53 in an inactive state on chromatin at promoters of a subset of it's target genes..
Protein Sequence	MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYFICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEALGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDLSDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLETGAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPSRLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLTNGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKDMMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERRDIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSGFDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAKEEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEPHVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLGRRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKARYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTERPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNLSLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGDGDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEALEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVDEDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPDDRSQDSTAVALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQGATEERGKNEESLESTEGFRAAEQGVQKPAAETPASACIPGKPSASTPTLWDGKKRGDLPGEPVAFPQGLPAGAEEQRQFLTEQCIASFRLCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSIVLLLKVLAQLRDHSTLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELAEGSERPGPKVCGLPGARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQPTPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDYMDI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
10	Phosphorylation	RIAALNASSTIEDDH EEEEECCCCCCCCCC	27.26	29255136
11	Phosphorylation	IAALNASSTIEDDHE EEEECCCCCCCCCCC	30.87	23401153
12	Phosphorylation	AALNASSTIEDDHEG EEECCCCCCCCCCCC	26.37	29255136
20	Phosphorylation	IEDDHEGSFKSHKTQ CCCCCCCCCCCCCCC	26.90	30266825
22	Acetylation	DDHEGSFKSHKTQTK CCCCCCCCCCCCCCH	54.04	26051181
22	Ubiquitination	DDHEGSFKSHKTQTK CCCCCCCCCCCCCCH	54.04	-
23	Phosphorylation	DHEGSFKSHKTQTKE CCCCCCCCCCCCCHH	28.36	23312004
25	Ubiquitination	EGSFKSHKTQTKEAQ CCCCCCCCCCCHHHH	49.79	-
29	Ubiquitination	KSHKTQTKEAQEAEA CCCCCCCHHHHHHHH	41.03	-
42	Ubiquitination	EAFALYHKALDLQKH HHHHHHHHHHHHHHC	36.77	-
48	Ubiquitination	HKALDLQKHDRFEES HHHHHHHHCHHHHHH	55.56	-
57	Ubiquitination	DRFEESAKAYHELLE HHHHHHHHHHHHHHH	59.77	-
66	Phosphorylation	YHELLEASLLREAVS HHHHHHHHHHHHHHH	20.68	30266825
74	Phosphorylation	LLREAVSSGDEKEGL HHHHHHHCCCCCCCC	43.60	28985074
78	Ubiquitination	AVSSGDEKEGLKHPG HHHCCCCCCCCCCCC	62.92	-
78	Ubiquitination	AVSSGDEKEGLKHPG HHHCCCCCCCCCCCC	62.92	-
82	Ubiquitination	GDEKEGLKHPGLILK CCCCCCCCCCCEEEE	59.62	-
82	Ubiquitination	GDEKEGLKHPGLILK CCCCCCCCCCCEEEE	59.62	-
89	Ubiquitination	KHPGLILKYSTYKNL CCCCEEEEHHHHHCH	30.11	-
193	Ubiquitination	EKDCRYSKGLVLKEK HCCCCCCCCCCHHHH	47.53	-
198	Ubiquitination	YSKGLVLKEKIFEEQ CCCCCCHHHHHHCCC	49.86	-
200	Ubiquitination	KGLVLKEKIFEEQPC CCCCHHHHHHCCCCC	51.62	-
260	Ubiquitination	REKEPDLKLVQPIPF ECCCCCCCCCCCCCC	54.73	-
349	O-linked_Glycosylation	YTSVATTSFPLHSPG EECEEECCCCCCCCC	22.10	OGP
374	Ubiquitination	ISGGDKSKKGVKRKK CCCCCCCCCCCCHHH	60.32	-
383	Phosphorylation	GVKRKKISEESGETA CCCHHHCCHHHHHHH	44.16	28985074
386	Phosphorylation	RKKISEESGETAKRR HHHCCHHHHHHHHHH	37.57	21815630
391	Acetylation	EESGETAKRRSARVR HHHHHHHHHHHHHHH	56.62	25953088
394	Ubiquitination	GETAKRRSARVRNTK HHHHHHHHHHHHCCC	25.18	-
394	Phosphorylation	GETAKRRSARVRNTK HHHHHHHHHHHHCCC	25.18	27282143
415	Sulfoxidation	VDFQELLMKFLPSRL CCHHHHHHHHHHHHH	4.51	21406390
424	Ubiquitination	FLPSRLRKLDPEEED HHHHHHHCCCCCCCC	62.93	-
433	Phosphorylation	DPEEEDDSFNNYEVQ CCCCCCCCCCCCCCC	42.04	23401153
437	Phosphorylation	EDDSFNNYEVQSEAK CCCCCCCCCCCCHHH	20.69	28122231
441	Phosphorylation	FNNYEVQSEAKLESF CCCCCCCCHHHHHCC	44.70	24732914
444	Ubiquitination	YEVQSEAKLESFPSI CCCCCHHHHHCCCCC	49.05	-
447	Phosphorylation	QSEAKLESFPSIGPQ CCHHHHHCCCCCCCC	53.55	25159151
450	Phosphorylation	AKLESFPSIGPQRLS HHHHCCCCCCCCCCC	37.86	25159151
457	Phosphorylation	SIGPQRLSFDSATFM CCCCCCCCCCCCCCC	29.24	28102081
460	Phosphorylation	PQRLSFDSATFMESE CCCCCCCCCCCCHHH	27.48	28102081
462	Phosphorylation	RLSFDSATFMESEKQ CCCCCCCCCCHHHCC	27.71	28102081
480	Phosphorylation	EFLLENLTNGGILEL HHHHHCCCCCHHHHH	43.32	26074081
491	Phosphorylation	ILELMMRYLKAMGHK HHHHHHHHHHHCCCC	8.48	-
547	Phosphorylation	DMMLMSLSCMELQLD HHHHHHHHHHHHHHH	12.24	22468782
567	Phosphorylation	KGRSSAVSPRNCPAG CCCCCCCCCCCCCCC	20.19	24719451
635	Ubiquitination	QGDMEQALENYDICT HCCHHHHHHHHHHHH	4.36	-
656	Ubiquitination	TAIQVEAGAERRDIV CCEEECCCCCCCCEE	17.92	-
673	Phosphorylation	LPNLHNDSVVSLEEI CCCCCCCCCCCHHHH	29.72	21712546
685	Ubiquitination	EEIDKNLKSLERCQS HHHHHHHHHHHHHCC	63.49	-
706	Ubiquitination	LYEAGDYKAVVHLLR HHHCCCHHHHHHHHC	39.17	-
746	Phosphorylation	QLLLLQDSLLRLKDY HHHHHHHHHHCCCCH	19.15	24719451
753	Phosphorylation	SLLRLKDYRQCFECS HHHCCCCHHHHHCCH	10.86	-
802	Phosphorylation	EQALSADSSGSILKV HHHHCCCCCCCEEEE	35.99	-
805	Phosphorylation	LSADSSGSILKVSSS HCCCCCCCEEEECCC	27.05	24719451
830	Phosphorylation	LIQVIDCSMAVQEEA CHHHHHHHHHHHHHH	13.16	-
947	Ubiquitination	ETALEQCFYCLYSFP HHHHHHHHHHHHHCC	4.89	-
948	Phosphorylation	TALEQCFYCLYSFPS HHHHHHHHHHHHCCC	6.81	-
951	Phosphorylation	EQCFYCLYSFPSKKS HHHHHHHHHCCCHHH	12.52	-
995	Phosphorylation	KTLPEFDSYKTSTVS CCCCCCCCCCCCCCC	33.57	22210691
996	Phosphorylation	TLPEFDSYKTSTVSA CCCCCCCCCCCCCCH	21.82	22210691
997	Ubiquitination	LPEFDSYKTSTVSAD CCCCCCCCCCCCCHH	39.69	-
1014	Phosphorylation	NLLKRIATIVPRTER HHHHHHHHCCCCCCC	21.82	27251275
1106	Acetylation	RASRIQDKLNSNELK HHHHHHHHHHCCCCC	32.94	25953088
1112	Ubiquitination	DKLNSNELKSDGPIW HHHHCCCCCCCCCHH	8.23	-
1113	Ubiquitination	KLNSNELKSDGPIWK HHHCCCCCCCCCHHH	40.08	-
1138	Ubiquitination	RALEIDSSNLSLWIE HHHHCCCCCCEEEEE	37.73	-
1148	Phosphorylation	SLWIEYGTMSYALHS EEEEEHHHHHHHHHH	11.31	-
1162	Ubiquitination	SFASRQLKQWRGELP HHHHHHHHHHCCCCC	39.20	-
1188	Ubiquitination	DSMLETAKHCFTSAA HHHHHHHHHHHHHHH	48.61	-
1210	Phosphorylation	EEEWLIHYMLGKVAE HHHHHHHHHHHHHHH	6.24	26546556
1227	Ubiquitination	QQPPTVYLLHYRQAG CCCCEEEEEEEHHHH	1.75	-
1270	Phosphorylation	VYFRLHASILKLLGK HHHHHHHHHHHHHCC	20.08	24719451
1273 (in isoform 2)	Phosphorylation	-	39.74	27732954
1275 (in isoform 2)	Phosphorylation	-	8.72	27732954
1276 (in isoform 2)	Phosphorylation	-	50.30	27732954
1277	Ubiquitination	SILKLLGKPDSGVGA HHHHHHCCCCCCCCH	45.69	-
1279 (in isoform 2)	Phosphorylation	-	62.60	27732954
1323	Phosphorylation	ACLVDEDSHSSAGTL HEEECCCCCCCCCCC	24.18	26074081
1325	Phosphorylation	LVDEDSHSSAGTLPG EECCCCCCCCCCCCC	26.32	26074081
1326	Phosphorylation	VDEDSHSSAGTLPGP ECCCCCCCCCCCCCC	25.87	26074081
1329	Phosphorylation	DSHSSAGTLPGPGAS CCCCCCCCCCCCCCC	29.51	26074081
1336	Phosphorylation	TLPGPGASLPSSSGP CCCCCCCCCCCCCCC	46.88	26074081
1339	Phosphorylation	GPGASLPSSSGPGLT CCCCCCCCCCCCCCC	42.29	26074081
1340	Phosphorylation	PGASLPSSSGPGLTS CCCCCCCCCCCCCCC	37.06	26074081
1341	Phosphorylation	GASLPSSSGPGLTSP CCCCCCCCCCCCCCC	54.03	26074081
1345	Acetylation	PSSSGPGLTSPPYTA CCCCCCCCCCCCCCC	4.89	-
1346	Phosphorylation	SSSGPGLTSPPYTAT CCCCCCCCCCCCCCC	45.14	25002506
1347	Phosphorylation	SSGPGLTSPPYTATP CCCCCCCCCCCCCCC	28.99	25002506
1350	Phosphorylation	PGLTSPPYTATPIDH CCCCCCCCCCCCCCC	16.64	25002506
1351	Phosphorylation	GLTSPPYTATPIDHD CCCCCCCCCCCCCCC	29.81	25002506
1353	Phosphorylation	TSPPYTATPIDHDYV CCCCCCCCCCCCCCC	16.99	25002506
1359	Phosphorylation	ATPIDHDYVKCKKPH CCCCCCCCCCCCCCC	9.82	25002506
1370	Phosphorylation	KKPHQQATPDDRSQD CCCCCCCCCCCCCCC	23.94	30576142
1375	Phosphorylation	QATPDDRSQDSTAVA CCCCCCCCCCCCEEE	45.38	27732954
1378	Phosphorylation	PDDRSQDSTAVALSD CCCCCCCCCEEECCC	15.61	27732954
1379	Phosphorylation	DDRSQDSTAVALSDS CCCCCCCCEEECCCC	33.18	27732954
1388	Phosphorylation	VALSDSSSTQDFFNE EECCCCCCCHHHHCC	33.76	-
1389	Phosphorylation	ALSDSSSTQDFFNEP ECCCCCCCHHHHCCC	33.82	30576142
1398	Phosphorylation	DFFNEPTSLLEGSRK HHHCCCHHHHCCCCC	41.49	24275569
1403	Phosphorylation	PTSLLEGSRKSYTEK CHHHHCCCCCCCHHH	27.45	20860994
1424	Acetylation	SQAGATGKDLQGATE CCCCCCCCCCCCHHH	51.41	23236377
1435	Acetylation	GATEERGKNEESLES CHHHHCCCCHHHHHH	68.36	26051181
1439	Phosphorylation	ERGKNEESLESTEGF HCCCCHHHHHHHHHH	31.12	23401153
1442	Phosphorylation	KNEESLESTEGFRAA CCHHHHHHHHHHHHH	36.73	29255136
1443	Phosphorylation	NEESLESTEGFRAAE CHHHHHHHHHHHHHH	30.65	23927012
1471	Phosphorylation	ACIPGKPSASTPTLW HCCCCCCCCCCCCCC	38.03	25627689
1474	Phosphorylation	PGKPSASTPTLWDGK CCCCCCCCCCCCCCC	21.73	25159151
1481	Acetylation	TPTLWDGKKRGDLPG CCCCCCCCCCCCCCC	36.50	26051181
1509	Phosphorylation	EEQRQFLTEQCIASF HHHHHHHHHHHHHHH	25.87	21406692
1515	Phosphorylation	LTEQCIASFRLCLSR HHHHHHHHHHHHHHH	7.32	20068231
1605	Phosphorylation	FAWHMNRSIVLLLKV CHHHCHHHHHHHHHH	16.43	30576142
1620	Phosphorylation	LAQLRDHSTLLKVSS HHHCCCCHHHHHHHH	25.66	20068231
1621	Phosphorylation	AQLRDHSTLLKVSSM HHCCCCHHHHHHHHH	32.46	20068231
1626	Phosphorylation	HSTLLKVSSMLQRTP CHHHHHHHHHHHHCC	14.40	20068231
1627	Phosphorylation	STLLKVSSMLQRTPD HHHHHHHHHHHHCCC	26.88	20068231
1663	Phosphorylation	TVKVLEDTLSELAEG HHHHHHHHHHHHHCC	23.86	25921289
1665	Phosphorylation	KVLEDTLSELAEGSE HHHHHHHHHHHCCCC	32.43	25921289
1671	Phosphorylation	LSELAEGSERPGPKV HHHHHCCCCCCCCCC	23.18	25921289
1677	Ubiquitination	GSERPGPKVCGLPGA CCCCCCCCCCCCCCC	56.95	-
1687	Phosphorylation	GLPGARMTTDVSHKA CCCCCEECCCCCCCC	17.81	23186163
1688	Phosphorylation	LPGARMTTDVSHKAS CCCCEECCCCCCCCC	25.68	23186163
1691	Phosphorylation	ARMTTDVSHKASPED CEECCCCCCCCCCCC	23.29	23917254
1693	Acetylation	MTTDVSHKASPEDGQ ECCCCCCCCCCCCCC	42.95	26051181
1695	Phosphorylation	TDVSHKASPEDGQEG CCCCCCCCCCCCCCC	33.36	21815630
1715	Phosphorylation	KPPLADGSGPGPEPG CCCCCCCCCCCCCCC	42.22	28555341
1724	Acetylation	PGPEPGGKVGLLNHR CCCCCCCCEECCCCC	38.76	26051181
1740	Phosphorylation	VAMDAGDSADQSGER EEECCCCCCCCCCCC	32.59	23401153
1744	Phosphorylation	AGDSADQSGERKDKE CCCCCCCCCCCCCCC	43.07	30108239
1752	Phosphorylation	GERKDKESPRAGPTE CCCCCCCCCCCCCCC	25.98	25849741
1758	Phosphorylation	ESPRAGPTEPMDTSE CCCCCCCCCCCCCCC	52.37	27251275
1763	Phosphorylation	GPTEPMDTSEATVCH CCCCCCCCCCCEEEC	23.39	29255136
1764	Phosphorylation	PTEPMDTSEATVCHS CCCCCCCCCCEEECH	22.44	29255136
1767	Phosphorylation	PMDTSEATVCHSDLE CCCCCCCEEECHHHC	21.44	29255136
1771	Phosphorylation	SEATVCHSDLERTPP CCCEEECHHHCCCCC	38.47	29255136
1776	Phosphorylation	CHSDLERTPPLLPGR ECHHHCCCCCCCCCC	21.63	28985074
1792	Phosphorylation	ARDRGPESRPTELSL CCCCCCCCCCCCCCH	46.85	30108239
1795	Phosphorylation	RGPESRPTELSLEEL CCCCCCCCCCCHHHH	48.74	30108239
1798	Phosphorylation	ESRPTELSLEELSIS CCCCCCCCHHHHCCC	27.74	30108239
1803	Phosphorylation	ELSLEELSISARQQP CCCHHHHCCCCCCCC	20.13	30108239
1805	Phosphorylation	SLEELSISARQQPTP CHHHHCCCCCCCCCC	17.64	30108239
1811	Phosphorylation	ISARQQPTPLTPAQP CCCCCCCCCCCCCCC	26.96	29978859
1814	Phosphorylation	RQQPTPLTPAQPAPA CCCCCCCCCCCCCCC	20.13	26657352
1826	Phosphorylation	APAPAPATTTGTRAG CCCCCCCCCCCCCCC	24.67	28555341
1831	Methylation	PATTTGTRAGGHPEE CCCCCCCCCCCCCCC	32.36	-
1855	O-linked_Glycosylation	KLLEDTESGKTLLLD HHHHCCCCCCEEEHH	47.91	30379171
1855	Phosphorylation	KLLEDTESGKTLLLD HHHHCCCCCCEEEHH	47.91	-
1857	Ubiquitination	LEDTESGKTLLLDAY HHCCCCCCEEEHHHH	45.32	-
1864	Phosphorylation	KTLLLDAYRVWQQGQ CEEEHHHHHHHHCCC	12.83	-
1876	Phosphorylation	QGQKGVAYDLGRVER CCCCCCCCHHHHHHH	14.86	-
1886	Phosphorylation	GRVERIMSETYMLIK HHHHHHHHHHHHHHH	25.15	24260401
1888	Phosphorylation	VERIMSETYMLIKQV HHHHHHHHHHHHHHC	13.61	25404012
1889	Phosphorylation	ERIMSETYMLIKQVD HHHHHHHHHHHHHCC	5.95	24247654
1906	Ubiquitination	AALEQAVKFCQVHLG HHHHHHHHHHHHHHH	43.36	-
1921	Phosphorylation	AAAQRQASGDTPTTP HHHHHHHCCCCCCCC	28.94	29255136
1924	Phosphorylation	QRQASGDTPTTPKHP HHHHCCCCCCCCCCC	26.51	29255136
1926	Phosphorylation	QASGDTPTTPKHPKD HHCCCCCCCCCCCCC	58.80	29255136
1927	Phosphorylation	ASGDTPTTPKHPKDS HCCCCCCCCCCCCCC	31.38	29255136
1934	Phosphorylation	TPKHPKDSRENFFPV CCCCCCCCCCCCCCE	47.85	28111955
2005	Phosphorylation	RPHRPEATPSMASLG CCCCCCCCCCHHHCC	17.77	24247654
2010	Phosphorylation	EATPSMASLGPEGEE CCCCCHHHCCCCHHH	25.80	28555341
2035	Phosphorylation	PPQEPRHSPQVKMAP CCCCCCCCCCCCCCC	20.50	25159151
2043	Phosphorylation	PQVKMAPTSSPAEPH CCCCCCCCCCCCCCC	32.09	30108239
2044	Phosphorylation	QVKMAPTSSPAEPHC CCCCCCCCCCCCCCC	33.01	30108239
2045	Phosphorylation	VKMAPTSSPAEPHCW CCCCCCCCCCCCCCC	30.52	30108239
2060	Phosphorylation	PAEAALGTGAEPTCS CCHHHCCCCCCCCCC	33.78	26074081
2065	Phosphorylation	LGTGAEPTCSQEGKL CCCCCCCCCCCCCCC	19.12	26074081
2067	Phosphorylation	TGAEPTCSQEGKLRP CCCCCCCCCCCCCCC	33.47	30108239
2071	Acetylation	PTCSQEGKLRPEPRR CCCCCCCCCCCCCCC	40.34	26051181
2089	Phosphorylation	AQEAASETQPLSSPP HHHHHHCCCCCCCCC	32.75	17525332
2093	Phosphorylation	ASETQPLSSPPTAAS HHCCCCCCCCCCCCC	47.70	30266825
2094	Phosphorylation	SETQPLSSPPTAASS HCCCCCCCCCCCCCC	42.45	17525332
2097	Phosphorylation	QPLSSPPTAASSKAP CCCCCCCCCCCCCCC	37.93	30266825
2100	Phosphorylation	SSPPTAASSKAPSSG CCCCCCCCCCCCCCC	29.88	30108239
2101	Phosphorylation	SPPTAASSKAPSSGS CCCCCCCCCCCCCCC	28.27	28450419
2106	Phosphorylation	ASSKAPSSGSAQPPE CCCCCCCCCCCCCCC	35.39	28555341
2118	Acetylation	PPEGHPGKPEPSRAK CCCCCCCCCCCCCCC	51.13	25953088
2139	Phosphorylation	MPKLVIPSAATKFPP CCCEECCCCCCCCCC	21.29	28450419
2142	Phosphorylation	LVIPSAATKFPPEIT EECCCCCCCCCCCCE	32.70	28450419
2149	Phosphorylation	TKFPPEITVTPPTPT CCCCCCCEECCCCCC	19.37	29255136
2151	Phosphorylation	FPPEITVTPPTPTLL CCCCCEECCCCCCCC	18.20	29255136
2154	Phosphorylation	EITVTPPTPTLLSPK CCEECCCCCCCCCCC	30.06	29255136
2156	Phosphorylation	TVTPPTPTLLSPKGS EECCCCCCCCCCCCC	42.69	29255136
2159	Phosphorylation	PPTPTLLSPKGSISE CCCCCCCCCCCCCCH	27.90	29255136
2163	Phosphorylation	TLLSPKGSISEETKQ CCCCCCCCCCHHHHH	29.12	26074081
2165	Phosphorylation	LSPKGSISEETKQKL CCCCCCCCHHHHHHH	30.95	26074081
2173	Methylation	EETKQKLKSAILSAQ HHHHHHHHHHHHHHH	44.89	-
2181	Phosphorylation	SAILSAQSAANVRKE HHHHHHHHHHHHCHH	29.12	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
2126	S	Phosphorylation	Kinase	CAMK4	Q16566	GPS
-	K	Ubiquitination	E3 ubiquitin ligase	FBXO32	Q969P5	PMID:18235241

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CABIN_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CABIN_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SIN3A_HUMAN	SIN3A	physical	10933397
MEF2B_HUMAN	MEF2BNB-MEF2B	physical	10531067
MEF2D_HUMAN	MEF2D	physical	10531067
DYN1_HUMAN	DNM1	physical	10931822
AMPH_HUMAN	AMPH	physical	10931822
AP1B1_HUMAN	AP1B1	physical	10931822
SUV91_HUMAN	SUV39H1	physical	17172641
MEF2D_HUMAN	MEF2D	physical	15902271
1433T_HUMAN	YWHAQ	physical	15902271
HIRA_HUMAN	HIRA	physical	22195966
UBN1_HUMAN	UBN1	physical	22195966
RPB1_HUMAN	POLR2A	physical	22195966

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CABIN_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"ATM and ATR substrate analysis reveals extensive protein networksresponsive to DNA damage."; Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III,Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.,Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.; Science 316:1160-1166(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-2089, AND MASSSPECTROMETRY.	17525332 [Abstract]