| UniProt ID | ARC5_ARATH | |
|---|---|---|
| UniProt AC | Q84N64 | |
| Protein Name | Dynamin-like protein ARC5 | |
| Gene Name | ARC5 | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 777 | |
| Subcellular Localization |
Cytoplasm. Plastid, chloroplast outer membrane Peripheral membrane protein. Peroxisome. Plastid equatorial positioning (in a discontinuous ring shape) mediated by PDV2 in complex with ARC6 and by PDV1. |
|
| Protein Description | Probable GTPase component of both plastid and peroxisme division machinery. Required for the last steps of plastid division specifically in mesophyll-cell, when the narrow isthmus breaks, facilitating the separation of the daughter plastids. Necessary for peroxisome activities. Seems to influence stromule (stroma-filled tubular extensions of the plastid envelope membrane) length and frequency.. | |
| Protein Sequence | MAEVSAKSVTVEEMAEEDDAAIEERWSLYEAYNELHALAQELETPFEAPAVLVVGQQTDGKSALVEALMGFQFNHVGGGTKTRRPITLHMKYDPQCQFPLCHLGSDDDPSVSLPKSLSQIQAYIEAENMRLEQEPCSPFSAKEIIVKVQYKYCPNLTIIDTPGLIAPAPGLKNRALQVQARAVEALVRAKMQHKEFIILCLEDSSDWSIATTRRIVMQVDPELSRTIVVSTKLDTKIPQFSCSSDVEVFLSPPASALDSSLLGDSPFFTSVPSGRVGYGQDSVYKSNDEFKQAVSLREMEDIASLEKKLGRLLTKQEKSRIGISKLRLFLEELLWKRYKESVPLIIPLLGKEYRSTVRKLDTVSKELSSLDEAKLKERGRTFHDLFLTKLSLLLKGTVVAPPDKFGETLQDERTQGGAFVGTDGLQFSHKLIPNAGMRLYGGAQYHRAMAEFRFLVGAIKCPPITREEIVNACGVEDIHDGTNYSRTACVIAVAKARETFEPFLHQLGARLLHILKRLLPISVYLLQKEGEYLSGHEVFLKRVASAFNSFVESTEKSCRDKCMEDLASTTRYVTWSLHNKNRAGLRQFLDSFGGTEHNTTSGNAIGFSLPQDALGGTTDTKSRSDVKLSHLASNIDSGSSIQTTEMRLADLLDSTLWNRKLAPSSERIVYALVQQIFQGIREYFLASAELKFNCFLLMPIVDKLPALLREELENAFEDDLDSIFDITNLRQSLDQKKRSTEIELRRIKRIKEKFRVMNEKLNSHEFAQNLKAPSVQH | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 599 | Phosphorylation | FGGTEHNTTSGNAIG CCCCCCCCCCCCCCE | 25.01 | 19880383 | |
| 600 | Phosphorylation | GGTEHNTTSGNAIGF CCCCCCCCCCCCCEE | 39.70 | 19880383 | |
| 617 | Phosphorylation | PQDALGGTTDTKSRS CCHHCCCCCCCCCHH | 21.50 | 19880383 | |
| 618 | Phosphorylation | QDALGGTTDTKSRSD CHHCCCCCCCCCHHH | 44.97 | 19880383 | |
| 633 | Phosphorylation | VKLSHLASNIDSGSS HCHHHHHHCCCCCCC | 40.45 | 23111157 | |
| 639 | Phosphorylation | ASNIDSGSSIQTTEM HHCCCCCCCCCHHHH | 28.37 | 23111157 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ARC5_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ARC5_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ARC5_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| ARC5_ARATH | ARC5 | physical | 20179140 | |
| DRP3A_ARATH | DRP3A | physical | 20179140 | |
| DRP3B_ARATH | DRP3B | physical | 20179140 | |
| FIS1A_ARATH | BIGYIN | physical | 20179140 | |
| PX11A_ARATH | PEX11A | physical | 20179140 | |
| PX11B_ARATH | PEX11B | physical | 20179140 | |
| PX11C_ARATH | PEX11C | physical | 20179140 | |
| PX11D_ARATH | PEX11D | physical | 20179140 | |
| ARC5_ARATH | ARC5 | physical | 23595201 | |
| PDV1_ARATH | PDV1 | physical | 23595201 | |
| PDV2_ARATH | PDV2 | physical | 23595201 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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