ARC5_ARATH - dbPTM
ARC5_ARATH - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ARC5_ARATH
UniProt AC Q84N64
Protein Name Dynamin-like protein ARC5
Gene Name ARC5
Organism Arabidopsis thaliana (Mouse-ear cress).
Sequence Length 777
Subcellular Localization Cytoplasm. Plastid, chloroplast outer membrane
Peripheral membrane protein. Peroxisome. Plastid equatorial positioning (in a discontinuous ring shape) mediated by PDV2 in complex with ARC6 and by PDV1.
Protein Description Probable GTPase component of both plastid and peroxisme division machinery. Required for the last steps of plastid division specifically in mesophyll-cell, when the narrow isthmus breaks, facilitating the separation of the daughter plastids. Necessary for peroxisome activities. Seems to influence stromule (stroma-filled tubular extensions of the plastid envelope membrane) length and frequency..
Protein Sequence MAEVSAKSVTVEEMAEEDDAAIEERWSLYEAYNELHALAQELETPFEAPAVLVVGQQTDGKSALVEALMGFQFNHVGGGTKTRRPITLHMKYDPQCQFPLCHLGSDDDPSVSLPKSLSQIQAYIEAENMRLEQEPCSPFSAKEIIVKVQYKYCPNLTIIDTPGLIAPAPGLKNRALQVQARAVEALVRAKMQHKEFIILCLEDSSDWSIATTRRIVMQVDPELSRTIVVSTKLDTKIPQFSCSSDVEVFLSPPASALDSSLLGDSPFFTSVPSGRVGYGQDSVYKSNDEFKQAVSLREMEDIASLEKKLGRLLTKQEKSRIGISKLRLFLEELLWKRYKESVPLIIPLLGKEYRSTVRKLDTVSKELSSLDEAKLKERGRTFHDLFLTKLSLLLKGTVVAPPDKFGETLQDERTQGGAFVGTDGLQFSHKLIPNAGMRLYGGAQYHRAMAEFRFLVGAIKCPPITREEIVNACGVEDIHDGTNYSRTACVIAVAKARETFEPFLHQLGARLLHILKRLLPISVYLLQKEGEYLSGHEVFLKRVASAFNSFVESTEKSCRDKCMEDLASTTRYVTWSLHNKNRAGLRQFLDSFGGTEHNTTSGNAIGFSLPQDALGGTTDTKSRSDVKLSHLASNIDSGSSIQTTEMRLADLLDSTLWNRKLAPSSERIVYALVQQIFQGIREYFLASAELKFNCFLLMPIVDKLPALLREELENAFEDDLDSIFDITNLRQSLDQKKRSTEIELRRIKRIKEKFRVMNEKLNSHEFAQNLKAPSVQH
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
599PhosphorylationFGGTEHNTTSGNAIG
CCCCCCCCCCCCCCE
25.0119880383
600PhosphorylationGGTEHNTTSGNAIGF
CCCCCCCCCCCCCEE
39.7019880383
617PhosphorylationPQDALGGTTDTKSRS
CCHHCCCCCCCCCHH
21.5019880383
618PhosphorylationQDALGGTTDTKSRSD
CHHCCCCCCCCCHHH
44.9719880383
633PhosphorylationVKLSHLASNIDSGSS
HCHHHHHHCCCCCCC
40.4523111157
639PhosphorylationASNIDSGSSIQTTEM
HHCCCCCCCCCHHHH
28.3723111157

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ARC5_ARATH !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ARC5_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ARC5_ARATH !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ARC5_ARATHARC5physical
20179140
DRP3A_ARATHDRP3Aphysical
20179140
DRP3B_ARATHDRP3Bphysical
20179140
FIS1A_ARATHBIGYINphysical
20179140
PX11A_ARATHPEX11Aphysical
20179140
PX11B_ARATHPEX11Bphysical
20179140
PX11C_ARATHPEX11Cphysical
20179140
PX11D_ARATHPEX11Dphysical
20179140
ARC5_ARATHARC5physical
23595201
PDV1_ARATHPDV1physical
23595201
PDV2_ARATHPDV2physical
23595201

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ARC5_ARATH

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Related Literatures of Post-Translational Modification

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