DRP3A_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DRP3A_ARATH
• UniProt AC: Q8S944
• Protein Name: Dynamin-related protein 3A
• Gene Name: DRP3A
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 808
• Subcellular Localization: Mitochondrion . Peroxisome .
• Protein Description: Involved in the control of mitochondrial and peroxisomal division and morphology. In association with PEX11C, PEX11D, PEX11E and FIS1B, is involved in cell cycle-associated constitutive self-replication of preexisting peroxisomes..
• Protein Sequence: MTIEEVSGETPPSTPPSSSTPSPSSSTTNAAPLGSSVIPIVNKLQDIFAQLGSQSTIALPQVVVVGSQSSGKSSVLEALVGRDFLPRGNDICTRRPLVLQLLQTKSRANGGSDDEWGEFRHLPETRFYDFSEIRREIEAETNRLVGENKGVADTQIRLKISSPNVLNITLVDLPGITKVPVGDQPSDIEARIRTMILSYIKQDTCLILAVTPANTDLANSDALQIASIVDPDGHRTIGVITKLDIMDKGTDARKLLLGNVVPLRLGYVGVVNRCQEDILLNRTVKEALLAEEKFFRSHPVYHGLADRLGVPQLAKKLNQILVQHIKVLLPDLKSRISNALVATAKEHQSYGELTESRAGQGALLLNFLSKYCEAYSSLLEGKSEEMSTSELSGGARIHYIFQSIFVKSLEEVDPCEDLTDDDIRTAIQNATGPRSALFVPDVPFEVLVRRQISRLLDPSLQCARFIFEELIKISHRCMMNELQRFPVLRKRMDEVIGDFLREGLEPSEAMIGDIIDMEMDYINTSHPNFIGGTKAVEAAMHQVKSSRIPHPVARPKDTVEPDRTSSSTSQVKSRSFLGRQANGIVTDQGVVSADAEKAQPAANASDTRWGIPSIFRGGDTRAVTKDSLLNKPFSEAVEDMSHNLSMIYLKEPPAVLRPTETHSEQEAVEIQITKLLLRSYYDIVRKNIEDSVPKAIMHFLVNHTKRELHNVFIKKLYRENLFEEMLQEPDEIAVKRKRTQETLHVLQQAYRTLDELPLEADSVSAGMSKHQELLTSSKYSTSSSYSASPSTTRRSRRAGDQHQNGYGF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
10	Phosphorylation	IEEVSGETPPSTPPS CEECCCCCCCCCCCC	43.98	23328941
13	Phosphorylation	VSGETPPSTPPSSST CCCCCCCCCCCCCCC	55.54	27531888
14	Phosphorylation	SGETPPSTPPSSSTP CCCCCCCCCCCCCCC	45.02	24601666
349	Phosphorylation	ATAKEHQSYGELTES HHHHHHHHHHCCCCC	36.69	29654922
573	Phosphorylation	SSTSQVKSRSFLGRQ CCCHHHHCHHHCCCC	34.01	27545962
575	Phosphorylation	TSQVKSRSFLGRQAN CHHHHCHHHCCCCCC	31.73	23111157
786	Phosphorylation	YSTSSSYSASPSTTR CCCCCCCCCCCCCCC	24.99	19880383
788	Phosphorylation	TSSSYSASPSTTRRS CCCCCCCCCCCCCCC	17.28	22631563
790	Phosphorylation	SSYSASPSTTRRSRR CCCCCCCCCCCCCCC	39.66	22631563
791	Phosphorylation	SYSASPSTTRRSRRA CCCCCCCCCCCCCCC	27.92	22631563

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DRP3A_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DRP3A_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DRP3A_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DRP3A_ARATH	DRP3A	physical	19144001
DRP3B_ARATH	DRP3B	physical	19144001
DRP3A_ARATH	DRP3A	physical	20231465
DRP3A_ARATH	DRP3A	physical	25462567

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.