PDV2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PDV2_ARATH
• UniProt AC: Q9XII1
• Protein Name: Plastid division protein PDV2
• Gene Name: PDV2
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 307
• Subcellular Localization: Plastid, chloroplast outer membrane ; Single-pass membrane protein . Plastid equatorial positioning in a discontinuous ring mediated by ARC6.
• Protein Description: Component of the plastid division machinery. Required to mediate the recruitment of ARC5 at the midplastid constriction site in the cytoplasm. Relays plastid division site position between stroma and outer surface via interactions with the cytoplasmic ARC5 and the inner membrane ARC6 that recruits stromal FtsZ ring..
• Protein Sequence: MEDEEGIGLILARATELRLKISDCIDNSSTTVSDNGDGNEDLSPGEGRKSEIIGNQDKDFDSISSEDVDEAEAERLLRIRDALEALESQLASLQNLRQRQQYEKQLALSEIDYSRKMLLEKLKEYKGKDFEVLRETTTFAGERVDYENDLLLPPYPVHPPLSLGLDNNNGYLSHLPSKKKSDANGFGSGHVRNEAEAKSPNGGSGGSSHGVIRFLGSVAKIVLPIIGVISLLSASGYGPEMRKRGASLNLFGLLPHRATRGKRTPNQCPPGKVLVIEDGEARCLVKERVEIPFDSVVAKRDVTYGYG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MEDEEGIG -------CCCHHCHH	15.35	22223895
31	Phosphorylation	CIDNSSTTVSDNGDG HCCCCCCEECCCCCC	21.69	29654922
33	Phosphorylation	DNSSTTVSDNGDGNE CCCCCEECCCCCCCC	24.22	30291188
50	Phosphorylation	SPGEGRKSEIIGNQD CCCCCCHHHHCCCCC	32.44	14593172
62	Phosphorylation	NQDKDFDSISSEDVD CCCCCCCCCCHHCCC	25.10	23111157
64	Phosphorylation	DKDFDSISSEDVDEA CCCCCCCCHHCCCHH	31.46	30291188
65	Phosphorylation	KDFDSISSEDVDEAE CCCCCCCHHCCCHHH	35.82	30291188
188	Phosphorylation	SDANGFGSGHVRNEA CCCCCCCCCCCCCCC	24.38	29654922
199	Phosphorylation	RNEAEAKSPNGGSGG CCCCEECCCCCCCCC	30.55	25561503
204	Phosphorylation	AKSPNGGSGGSSHGV ECCCCCCCCCCHHHH	41.18	29654922
207	Phosphorylation	PNGGSGGSSHGVIRF CCCCCCCCHHHHHHH	23.76	28295753
208	Phosphorylation	NGGSGGSSHGVIRFL CCCCCCCHHHHHHHH	27.77	28295753

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PDV2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PDV2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PDV2_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ARC6_ARATH	ARC6	physical	18812496
NIP11_ARATH	NLM1	physical	21798944
PDV1_ARATH	PDV1	physical	23595201
PDV2_ARATH	PDV2	physical	23595201

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteomic analysis of nuclei-enriched fractions fromArabidopsis thaliana.";
Jones A.M.E., MacLean D., Studholme D.J., Serna-Sanz A.,Andreasson E., Rathjen J.P., Peck S.C.;
J. Proteomics 72:439-451(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-64, AND MASSSPECTROMETRY.
PubMed: 19245862