AMMR1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: AMMR1_HUMAN
• UniProt AC: Q9Y4X0
• Protein Name: AMME syndrome candidate gene 1 protein
• Gene Name: AMMECR1
• Organism: Homo sapiens (Human).
• Sequence Length: 333
• Subcellular Localization: Nucleus .
• Protein Sequence: MAAGCCGVKKQKLSSSPPSGSGGGGGASSSSHCSGESQCRAGELGLGGAGTRLNGLGGLTGGGSGSGCTLSPPQGCGGGGGGIALSPPPSCGVGTLLSTPAAATSSSPSSSSAASSSSPGSRKMVVSAEMCCFCFDVLYCHLYGYQQPRTPRFTNEPYPLFVTWKIGRDKRLRGCIGTFSAMNLHSGLREYTLTSALKDSRFPPMTRDELPRLFCSVSLLTNFEDVCDYLDWEVGVHGIRIEFINEKGSKRTATYLPEVAKEQGWDHIQTIDSLLRKGGYKAPITNEFRKTIKLTRYRSEKMTLSYAEYLAHRQHHHFQNGIGHPLPPYNHYS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Sumoylation	AAGCCGVKKQKLSSS CCCCCCCCCCCCCCC	34.47	-
9	Sumoylation	AAGCCGVKKQKLSSS CCCCCCCCCCCCCCC	34.47	-
14	Phosphorylation	GVKKQKLSSSPPSGS CCCCCCCCCCCCCCC	35.49	23927012
15	Phosphorylation	VKKQKLSSSPPSGSG CCCCCCCCCCCCCCC	58.25	25159151
16	Phosphorylation	KKQKLSSSPPSGSGG CCCCCCCCCCCCCCC	37.14	23401153
19	Phosphorylation	KLSSSPPSGSGGGGG CCCCCCCCCCCCCCC	49.31	23927012
21	Phosphorylation	SSSPPSGSGGGGGAS CCCCCCCCCCCCCCC	38.31	23927012
28	Phosphorylation	SGGGGGASSSSHCSG CCCCCCCCCCCCCCC	33.74	29632367
29	Phosphorylation	GGGGGASSSSHCSGE CCCCCCCCCCCCCCC	35.01	23663014
30	Phosphorylation	GGGGASSSSHCSGES CCCCCCCCCCCCCCC	22.93	29632367
31	Phosphorylation	GGGASSSSHCSGESQ CCCCCCCCCCCCCCC	30.38	29632367
34	Phosphorylation	ASSSSHCSGESQCRA CCCCCCCCCCCCCCC	39.92	28450419
37	Phosphorylation	SSHCSGESQCRAGEL CCCCCCCCCCCCCCC	37.80	23927012
191	Phosphorylation	LHSGLREYTLTSALK CCCCCCEEEHHHHHH	10.70	26074081
192	Phosphorylation	HSGLREYTLTSALKD CCCCCEEEHHHHHHC	20.85	26074081
194	Phosphorylation	GLREYTLTSALKDSR CCCEEEHHHHHHCCC	12.26	26074081
195	Phosphorylation	LREYTLTSALKDSRF CCEEEHHHHHHCCCC	34.41	26074081
198	Ubiquitination	YTLTSALKDSRFPPM EEHHHHHHCCCCCCC	54.07	-
261	Ubiquitination	TYLPEVAKEQGWDHI ECCHHHHHHHCCCHH	56.60	-
273	Phosphorylation	DHIQTIDSLLRKGGY CHHHHHHHHHHCCCC	26.00	24719451
281	Ubiquitination	LLRKGGYKAPITNEF HHHCCCCCCCCCHHH	51.46	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of AMMR1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of AMMR1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of AMMR1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CACO2_HUMAN	CALCOCO2	physical	25416956
RBPMS_HUMAN	RBPMS	physical	25416956
ATL4_HUMAN	ADAMTSL4	physical	25416956
SEN54_HUMAN	TSEN54	physical	26186194
CLP1_HUMAN	CLP1	physical	26186194
PPIL4_HUMAN	PPIL4	physical	26186194
ALR_HUMAN	GFER	physical	26186194
ZN703_HUMAN	ZNF703	physical	26186194
HNRPF_HUMAN	HNRNPF	physical	28514442
PPIL4_HUMAN	PPIL4	physical	28514442
ALR_HUMAN	GFER	physical	28514442
CLP1_HUMAN	CLP1	physical	28514442
SEN54_HUMAN	TSEN54	physical	28514442
ZN507_HUMAN	ZNF507	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.