ZN625_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN625_HUMAN
• UniProt AC: Q96I27
• Protein Name: Zinc finger protein 625
• Gene Name: ZNF625
• Organism: Homo sapiens (Human).
• Sequence Length: 306
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MGERLLESKKDHQHGEILTQVPDDMLKKKTPRVKSCGEVSVGHASLNRHHRADTGHKPYEYQEYGQKPYKCTYCKKAFSDLPYFRTHEWAHTGGKPYDCEECGKSFISRSSIRRHRIMHSGDGPYKCNFCGKALMCLSLYLIHKRTHTGEKPYECKQCGKAFSHSGSLRIHERTHTGEKPYECSECGKAFHSSTCLHAHKITHTGEKPYECKQCGKAFVSFNSVRYHERTHTGEKPYECKQCGKAFRSASHLRTHGRTHTGEKPYECKQCGKAFGCASSVKIHERTHTGEKPCSSNTSKGQGEKIA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
10	Acetylation	ERLLESKKDHQHGEI HHHHHCCCCCCCCCH	70.49	11925409
29 (in isoform 2)	Phosphorylation	-	63.27	-
32	Dimethylation	MLKKKTPRVKSCGEV HHHCCCCCCEECCEE	54.44	-
32	Methylation	MLKKKTPRVKSCGEV HHHCCCCCCEECCEE	54.44	24377003
45	Phosphorylation	EVSVGHASLNRHHRA EEEECCCCCCCCCCC	22.09	29507054
48	Methylation	VGHASLNRHHRADTG ECCCCCCCCCCCCCC	32.08	24377009
48	Dimethylation	VGHASLNRHHRADTG ECCCCCCCCCCCCCC	32.08	-
108	Phosphorylation	ECGKSFISRSSIRRH HHHCCEECHHHHHHC	24.89	24719451
120	Phosphorylation	RRHRIMHSGDGPYKC HHCCEEECCCCCCCC	22.62	27732954
125	Phosphorylation	MHSGDGPYKCNFCGK EECCCCCCCCCCHHH	33.43	27732954
146	Phosphorylation	LYLIHKRTHTGEKPY HHHHHCCCCCCCCCE	28.70	29396449
148	Phosphorylation	LIHKRTHTGEKPYEC HHHCCCCCCCCCEEE	46.56	29496963
156	Sumoylation	GEKPYECKQCGKAFS CCCCEEECCCCCEEC	36.36	-
174	Phosphorylation	SLRIHERTHTGEKPY CEEEEECCCCCCCCE	22.32	-
176	Phosphorylation	RIHERTHTGEKPYEC EEEECCCCCCCCEEC	46.56	-
184	Phosphorylation	GEKPYECSECGKAFH CCCCEECCHHHCEEE	24.79	-
202	Phosphorylation	CLHAHKITHTGEKPY CCEEEECCCCCCCCE	20.42	29396449
204	Phosphorylation	HAHKITHTGEKPYEC EEEECCCCCCCCEEC	38.08	29496963
209	Phosphorylation	THTGEKPYECKQCGK CCCCCCCEECCCCCC	45.05	-
212	Sumoylation	GEKPYECKQCGKAFV CCCCEECCCCCCEEE	36.36	-
217	Ubiquitination	ECKQCGKAFVSFNSV ECCCCCCEEEEECCE	8.71	22505724
226	Phosphorylation	VSFNSVRYHERTHTG EEECCEEEECCCCCC	13.08	29083192
230	Phosphorylation	SVRYHERTHTGEKPY CEEEECCCCCCCCCC	22.32	29396449
232	Phosphorylation	RYHERTHTGEKPYEC EEECCCCCCCCCCCC	46.56	29496963
237	Phosphorylation	THTGEKPYECKQCGK CCCCCCCCCCCHHHH	45.05	29083192
240	Sumoylation	GEKPYECKQCGKAFR CCCCCCCCHHHHHHH	36.36	-
258	Phosphorylation	HLRTHGRTHTGEKPY HHHHCCCCCCCCCCE	28.51	29396449
260	Phosphorylation	RTHGRTHTGEKPYEC HHCCCCCCCCCCEEC	46.56	29496963
268	Sumoylation	GEKPYECKQCGKAFG CCCCEECCCCCCEEC	36.36	-
273	Ubiquitination	ECKQCGKAFGCASSV ECCCCCCEECCCCCC	7.43	22505724
286	Phosphorylation	SVKIHERTHTGEKPC CCEEEECCCCCCCCC	22.32	-
288	Phosphorylation	KIHERTHTGEKPCSS EEEECCCCCCCCCCC	46.56	-
301	Ubiquitination	SSNTSKGQGEKIA-- CCCCCCCCCCCCC--	61.68	22505724
329	Ubiquitination	------------------------------ ------------------------------		22505724

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN625_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN625_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN625_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
K1C40_HUMAN	KRT40	physical	25416956
KR107_HUMAN	KRTAP10-7	physical	25416956
KR109_HUMAN	KRTAP10-9	physical	25416956
KR103_HUMAN	KRTAP10-3	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.