ZN562_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN562_HUMAN
• UniProt AC: Q6V9R5
• Protein Name: Zinc finger protein 562
• Gene Name: ZNF562
• Organism: Homo sapiens (Human).
• Sequence Length: 426
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MSAFDMSHGFFPREPICPFEEKTKIGTMVEDHRSNSYQDSVTFDDVAVEFTPEEWALLDTTQKYLYRDVMLENYMNLASVDFFFCLTSEWEIQPRTKRSSLQQGFLKNQIFTGIQMQTRSYSGWKLCENCGEVFSEQFCLKTHMRAQNGGNTFEGNCYGKDSISVHKEASIGQELSKFNPCGKVFTLTPGLAVHLEILNGRQPYKCKECGKGFKYFASLDNHMGIHIGEKLCEFQECERAITTSSHLKQCVAVHTGKKSEKTKNCGKSFTNFSQLSAHAKTHKGEKSFECKECGRSFRNSSSFNVHIQIHTGIKPHKCTECGKAFTRSTHLTQHVRTHTGIKPYECKECGQAFTQYTGLAIHIRNHTGEKPYQCKECGKAFNRSSTLTQHRRIHTGEKPYECVECGKTFITSSHRSKHLKTHSGER

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
22	Ubiquitination	PICPFEEKTKIGTMV CCCCCCCCCCCCCEE	48.17	-
24	Ubiquitination	CPFEEKTKIGTMVED CCCCCCCCCCCEECC	50.64	-
100	Phosphorylation	QPRTKRSSLQQGFLK CCCCCCCHHHHCHHH	33.94	25159151
112	Phosphorylation	FLKNQIFTGIQMQTR HHHHCEEEEEEEEEC	34.70	-
160	Ubiquitination	FEGNCYGKDSISVHK CCCCEECCCCEEEEC	23.10	-
167	Ubiquitination	KDSISVHKEASIGQE CCCEEEECCHHHCCH	53.47	-
177	Ubiquitination	SIGQELSKFNPCGKV HHCCHHHCCCCCCCE	62.88	-
242	Phosphorylation	QECERAITTSSHLKQ HHHCHHHHCCHHHHH	21.46	22210691
245	Phosphorylation	ERAITTSSHLKQCVA CHHHHCCHHHHHHHH	30.65	22210691
262	Phosphorylation	TGKKSEKTKNCGKSF CCCCCHHCCCCCCCC	24.36	-
270	Phosphorylation	KNCGKSFTNFSQLSA CCCCCCCCCHHHHHH	42.31	25627689
280	Ubiquitination	SQLSAHAKTHKGEKS HHHHHHHHHCCCCCC	41.10	-
291	Ubiquitination	GEKSFECKECGRSFR CCCCEEECCCCCCCC	49.17	-
323	Ubiquitination	HKCTECGKAFTRSTH CCCCCCCCCCCCCCC	52.57	-
339	Phosphorylation	TQHVRTHTGIKPYEC HHHCHHCCCCCCEEC	39.73	28555341
344	Phosphorylation	THTGIKPYECKECGQ HCCCCCCEECCHHHH	29.02	-
385	Phosphorylation	GKAFNRSSTLTQHRR HCCCCCCCCCCCCCC	24.97	28555341
386	Phosphorylation	KAFNRSSTLTQHRRI CCCCCCCCCCCCCCC	34.76	28555341
395	Phosphorylation	TQHRRIHTGEKPYEC CCCCCCCCCCCCEEE	44.67	28111955
400	Phosphorylation	IHTGEKPYECVECGK CCCCCCCEEEEECCC	32.78	15592455
408	Phosphorylation	ECVECGKTFITSSHR EEEECCCEEEECHHH	12.93	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN562_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN562_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN562_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SMRCD_HUMAN	SMARCAD1	physical	26186194
CBX5_HUMAN	CBX5	physical	26186194
ZN561_HUMAN	ZNF561	physical	26186194
KBTB6_HUMAN	KBTBD6	physical	26186194
PRAME_HUMAN	PRAME	physical	26186194
ISLR_HUMAN	ISLR	physical	26186194
TRI39_HUMAN	TRIM39	physical	26186194
KNG1_HUMAN	KNG1	physical	26186194
RN187_HUMAN	RNF187	physical	26186194
TRI41_HUMAN	TRIM41	physical	26186194
ZN561_HUMAN	ZNF561	physical	28514442
TRI39_HUMAN	TRIM39	physical	28514442
SMRCD_HUMAN	SMARCAD1	physical	28514442
ISLR_HUMAN	ISLR	physical	28514442
RN187_HUMAN	RNF187	physical	28514442
KNG1_HUMAN	KNG1	physical	28514442
PRAME_HUMAN	PRAME	physical	28514442
TRI41_HUMAN	TRIM41	physical	28514442
CBX5_HUMAN	CBX5	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.