ZN561_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN561_HUMAN
• UniProt AC: Q8N587
• Protein Name: Zinc finger protein 561
• Gene Name: ZNF561
• Organism: Homo sapiens (Human).
• Sequence Length: 486
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MAAIYLSRGFFSREPICPFEEKTKVERMVEDYLASGYQDSVTFDDVAVDFTPEEWALLDTTEKYLYRDVMLENYMNLASVEWEIQPRTKRSSLQQGFLKNQIFSGIQMTRGYSGWKLCDCKNCGEVFREQFCLKTHMRVQNGGNTSEGNCYGKDTLSVHKEASTGQELSKFNPCGKVFTLTPGLAVHLEVLNARQPYKCKECGKGFKYFASLDNHMGIHTDEKLCEFQEYGRAVTASSHLKQCVAVHTGKKSKKTKKCGKSFTNFSQLYAPVKTHKGEKSFECKECGRSFRNSSCLNDHIQIHTGIKPHKCTYCGKAFTRSTQLTEHVRTHTGIKPYECKECGQAFAQYSGLSIHIRSHSGKKPYQCKECGKAFTTSTSLIQHTRIHTGEKPYECVECGKTFITSSRRSKHLKTHSGEKPFVCKICGKAFLYSSRLNVHLRTHTGEKPFVCKECGKAFAVSSRLSRHERIHTGEKPYECKDMSVTI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
22	Ubiquitination	PICPFEEKTKVERMV CCCCCCHHHHHHHHH	46.58	-
92	Phosphorylation	QPRTKRSSLQQGFLK CCCCCCHHHHHCHHH	33.94	25159151
160	Ubiquitination	KDTLSVHKEASTGQE CCCEEEEECCCCCCC	53.47	-
170	Ubiquitination	STGQELSKFNPCGKV CCCCCHHHCCCCCCE	62.88	-
261	Phosphorylation	KTKKCGKSFTNFSQL CCCCCCCCCCCHHHH	23.68	25159151
273	Sumoylation	SQLYAPVKTHKGEKS HHHCCCCCCCCCCCC	43.80	28112733
284	Ubiquitination	GEKSFECKECGRSFR CCCCEECCCCCCCCC	49.17	-
321	Phosphorylation	CGKAFTRSTQLTEHV CCCEECCCCCCHHHH	19.90	27251275
322	Phosphorylation	GKAFTRSTQLTEHVR CCEECCCCCCHHHHH	25.06	27251275
330	Phosphorylation	QLTEHVRTHTGIKPY CCHHHHHHCCCCCCE	23.77	27251275
332	Phosphorylation	TEHVRTHTGIKPYEC HHHHHHCCCCCCEEC	39.73	28555341
337	Phosphorylation	THTGIKPYECKECGQ HCCCCCCEECCHHHH	29.02	27251275
388	Phosphorylation	IQHTRIHTGEKPYEC HCCCEECCCCCCEEE	44.67	28111955
393	Phosphorylation	IHTGEKPYECVECGK ECCCCCCEEEEECCC	32.78	15592455
419	Ubiquitination	LKTHSGEKPFVCKIC CCCCCCCCCEEEEEC	47.48	-
424	Sumoylation	GEKPFVCKICGKAFL CCCCEEEEECCCEEE	35.41	-
424	Sumoylation	GEKPFVCKICGKAFL CCCCEEEEECCCEEE	35.41	28112733
442	Phosphorylation	RLNVHLRTHTGEKPF EEEEEECCCCCCCCE	30.10	-
444	Phosphorylation	NVHLRTHTGEKPFVC EEEECCCCCCCCEEE	46.56	29214152
447	Sumoylation	LRTHTGEKPFVCKEC ECCCCCCCCEEECCC	45.13	-
447	Ubiquitination	LRTHTGEKPFVCKEC ECCCCCCCCEEECCC	45.13	-
447	Sumoylation	LRTHTGEKPFVCKEC ECCCCCCCCEEECCC	45.13	-
452	Ubiquitination	GEKPFVCKECGKAFA CCCCEEECCCCCEEE	51.22	-
465	Phosphorylation	FAVSSRLSRHERIHT EEHHHCCCCCCCCCC	30.40	28555341
472	Phosphorylation	SRHERIHTGEKPYEC CCCCCCCCCCCCCCC	44.67	29496963

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN561_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN561_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN561_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN561_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.