ZN138_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN138_HUMAN
• UniProt AC: P52744
• Protein Name: Zinc finger protein 138
• Gene Name: ZNF138
• Organism: Homo sapiens (Human).
• Sequence Length: 262
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation as a repressor..
• Protein Sequence: MKRHEMVVAKHSALCSRFAQDLWLEQNIKDSFQKVTLSRYGKYGHKNLQLRKGCKSVDECKGHQGGFNGLNQCLKITTSKIFQCNKYVKVMHKFSNSNRHKIRHTENKHFRCKECDKSLCMLSRLTQHKKIHTRENFYKCEECGKTFNWSTNLSKPKKIHTGEKPYKCEVCGKAFHQSSILTKHKIIRTGEKPYKCAHCGKAFKQSSHLTRHKIIHTEEKPYKCEQCGKVFKQSPTLTKHQIIYTGEEPYKCEECGKAFNLS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
117	Ubiquitination	FRCKECDKSLCMLSR CCCCCCCHHHHHHHH	57.92	-
118	Phosphorylation	RCKECDKSLCMLSRL CCCCCCHHHHHHHHH	17.35	22210691
139	Ubiquitination	HTRENFYKCEECGKT CCCCCEEECHHHCCE	30.91	-
139	Sumoylation	HTRENFYKCEECGKT CCCCCEEECHHHCCE	30.91	-
154	Phosphorylation	FNWSTNLSKPKKIHT EECCCCCCCCCCCCC	49.32	24719451
161	Phosphorylation	SKPKKIHTGEKPYKC CCCCCCCCCCCCEEE	50.97	29496963
167	Sumoylation	HTGEKPYKCEVCGKA CCCCCCEEEEECCCC	32.23	-
170	Ubiquitination	EKPYKCEVCGKAFHQ CCCEEEEECCCCHHC	7.95	-
170	Sumoylation	EKPYKCEVCGKAFHQ CCCEEEEECCCCHHC	7.95	-
179	Phosphorylation	GKAFHQSSILTKHKI CCCHHCCCCHHHCCE	18.30	24719451
183	Acetylation	HQSSILTKHKIIRTG HCCCCHHHCCEEECC	39.18	19818627
185	Acetylation	SSILTKHKIIRTGEK CCCHHHCCEEECCCC	41.19	19818633
189	Ubiquitination	TKHKIIRTGEKPYKC HHCCEEECCCCCCCC	39.01	-
192	Phosphorylation	KIIRTGEKPYKCAHC CEEECCCCCCCCCCC	55.80	-
198	Sumoylation	EKPYKCAHCGKAFKQ CCCCCCCCCCCHHHC	30.27	-
198	Ubiquitination	EKPYKCAHCGKAFKQ CCCCCCCCCCCHHHC	30.27	-
220	Sumoylation	KIIHTEEKPYKCEQC CEEECCCCCCCCHHC	47.63	-
223	Sumoylation	HTEEKPYKCEQCGKV ECCCCCCCCHHCCCE	39.56	-
234	Phosphorylation	CGKVFKQSPTLTKHQ CCCEECCCCCCCCCE	22.05	-
238	Phosphorylation	FKQSPTLTKHQIIYT ECCCCCCCCCEEEEC	29.03	-
244	Phosphorylation	LTKHQIIYTGEEPYK CCCCEEEECCCCCEE	15.43	-
251	Sumoylation	YTGEEPYKCEECGKA ECCCCCEECCCCCCC	45.98	-
251	Sumoylation	YTGEEPYKCEECGKA ECCCCCEECCCCCCC	45.98	-
254	Sumoylation	EEPYKCEECGKAFNL CCCEECCCCCCCCCC	59.02	-
275	Phosphorylation	-------------------- --------------------		-
282	Sumoylation	--------------------------- ---------------------------		-
282	Ubiquitination	--------------------------- ---------------------------		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN138_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN138_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN138_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TRI41_HUMAN	TRIM41	physical	25416956
K1C40_HUMAN	KRT40	physical	25416956
KR108_HUMAN	KRTAP10-8	physical	25416956
KR103_HUMAN	KRTAP10-3	physical	25416956
ZBT8A_HUMAN	ZBTB8A	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.