ZDH11_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZDH11_HUMAN
• UniProt AC: Q9H8X9
• Protein Name: Probable palmitoyltransferase ZDHHC11
• Gene Name: ZDHHC11
• Organism: Homo sapiens (Human).
• Sequence Length: 412
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Sequence: MDTRSGSQCSVTPEAILNNEKLVLPPRISRVNGWSLPLHYFQVVTWAVFVGLSSATFGIFIPFLPHAWKYIAYVVTGGIFSFHLVVHLIASCIDPADSNVRLMKNYSQPMPLFDRSKHAHVIQNQFCHLCKVTVNKKTKHCISCNKCVSGFDHHCKWINNCVGSRNYWFFFSTVASATAGMLCLIAILLYVLVQYLVNPGVLRTDPRYEDVKNMNTWLLFLPLFPVQVQTLIVVIIGMLVLLLDFLGLVHLGQLLIFHIYLKAKKMTTFEYLINNRKEESSKHQAVRKDPYVQMDKGVLQQGAGALGSSAQGVKAKSSLLIHKHLCHFCTSVNQDGDSTAREGDEDPCPSALGAKARNSRLICRRLCQFSTRVHPDGGSMAQEADDAPSISTLGLQQETTEPMKTDSAESED

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MDTRSGSQCSVT ---CCCCCCCCCCCC	44.91	25693802
7	Phosphorylation	-MDTRSGSQCSVTPE -CCCCCCCCCCCCHH	29.29	25693802
10	Phosphorylation	TRSGSQCSVTPEAIL CCCCCCCCCCHHHHH	22.76	25693802
12	Phosphorylation	SGSQCSVTPEAILNN CCCCCCCCHHHHHCC	10.10	25693802
106	Phosphorylation	NVRLMKNYSQPMPLF CHHHCCCCCCCCCCC	11.81	22817900
149	Phosphorylation	ISCNKCVSGFDHHCK EECCCCCCCCHHHHH	43.12	-
208	Phosphorylation	VLRTDPRYEDVKNMN CCCCCCCHHHHCCCC	23.13	30301811
288	Ubiquitination	SKHQAVRKDPYVQMD HHCHHHHCCCCCCCC	57.36	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZDH11_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZDH11_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZDH11_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RETR2_HUMAN	FAM134A	physical	28514442
LNP_HUMAN	KIAA1715	physical	28514442
MK03_HUMAN	MAPK3	physical	28514442
CD032_HUMAN	C4orf32	physical	28514442
APOB_HUMAN	APOB	physical	28514442
EFNB1_HUMAN	EFNB1	physical	28514442
FGFR1_HUMAN	FGFR1	physical	28514442
PPM1A_HUMAN	PPM1A	physical	28514442
GLMN_HUMAN	GLMN	physical	28514442
AN13A_HUMAN	ANKRD13A	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.