Y1719_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: Y1719_ARATH
• UniProt AC: O04567
• Protein Name: Probable inactive receptor kinase At1g27190
• Gene Name: At1g27190
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 601
• Subcellular Localization: Membrane ; Single-pass membrane protein .
• Protein Sequence: MKKIFITLLWLLFISSFLCSSSSAEDDVLCLQGLKNSLIDPSSRLSSWSFPNSSASSICKLTGVSCWNEKENRIISLQLQSMQLAGEIPESLKLCRSLQSLDLSGNDLSGSIPSQICSWLPYLVTLDLSGNKLGGSIPTQIVECKFLNALILSDNKLSGSIPSQLSRLDRLRRLSLAGNDLSGTIPSELARFGGDDFSGNNGLCGKPLSRCGALNGRNLSIIIVAGVLGAVGSLCVGLVIFWWFFIREGSRKKKGYGAGKSKDDSDWIGLLRSHKLVQVTLFQKPIVKIKLGDLMAATNNFSSGNIDVSSRTGVSYKADLPDGSALAVKRLSACGFGEKQFRSEMNKLGELRHPNLVPLLGYCVVEDERLLVYKHMVNGTLFSQLHNGGLCDAVLDWPTRRAIGVGAAKGLAWLHHGCQPPYLHQFISSNVILLDDDFDARITDYGLAKLVGSRDSNDSSFNNGDLGELGYVAPEYSSTMVASLKGDVYGFGIVLLELVTGQKPLSVINGVEGFKGSLVDWVSQYLGTGRSKDAIDRSICDKGHDEEILQFLKIACSCVVSRPKERPTMIQVYESLKNMADKHGVSEHYDEFPLVFNKQEA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
52	N-linked_Glycosylation	LSSWSFPNSSASSIC CCCCCCCCCCHHHHH	46.73	-
139	Phosphorylation	KLGGSIPTQIVECKF CCCCCCCCHHHCCCC	29.29	19880383
265	Phosphorylation	AGKSKDDSDWIGLLR CCCCCCCCCHHHHHH	45.00	30291188
298	Phosphorylation	LGDLMAATNNFSSGN HHHHHHHCCCCCCCC	22.58	-
383	Phosphorylation	MVNGTLFSQLHNGGL HHCCCHHHHHHCCCC	34.64	-
399	Phosphorylation	DAVLDWPTRRAIGVG CEECCCCCHHHHCCC	28.65	-
456	Phosphorylation	KLVGSRDSNDSSFNN HHHCCCCCCCCCCCC	41.23	19880383
459	Phosphorylation	GSRDSNDSSFNNGDL CCCCCCCCCCCCCCC	40.87	19880383
460	Phosphorylation	SRDSNDSSFNNGDLG CCCCCCCCCCCCCCC	34.55	19880383
476	Phosphorylation	LGYVAPEYSSTMVAS HHEECCCCCCCCHHH	13.58	-
478	Phosphorylation	YVAPEYSSTMVASLK EECCCCCCCCHHHCC	21.44	-
479	Phosphorylation	VAPEYSSTMVASLKG ECCCCCCCCHHHCCC	15.10	-
483	Phosphorylation	YSSTMVASLKGDVYG CCCCCHHHCCCCEEE	21.14	-
586	Phosphorylation	MADKHGVSEHYDEFP HHHHCCCCCCCCCCC	24.21	23111157
589	Phosphorylation	KHGVSEHYDEFPLVF HCCCCCCCCCCCCEE	17.08	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of Y1719_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of Y1719_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of Y1719_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HHP2_ARATH	HHP2	physical	24833385
UBC32_ARATH	UBC32	physical	24833385
UBC34_ARATH	UBC34	physical	24833385
AB12I_ARATH	AT3G21580	physical	24833385
CNIH1_ARATH	AT3G12180	physical	24833385
CP21D_ARATH	AT3G66654	physical	24833385
WAK3_ARATH	WAK3	physical	24833385
BETL2_ARATH	AT1G29060	physical	24833385
BET12_ARATH	ATBET12	physical	24833385
TBL18_ARATH	TBL18	physical	24833385

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Site-specific phosphorylation profiling of Arabidopsis proteins bymass spectrometry and peptide chip analysis.";
de la Fuente van Bentem S., Anrather D., Dohnal I., Roitinger E.,Csaszar E., Joore J., Buijnink J., Carreri A., Forzani C.,Lorkovic Z.J., Barta A., Lecourieux D., Verhounig A., Jonak C.,Hirt H.;
J. Proteome Res. 7:2458-2470(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-586, AND MASSSPECTROMETRY.
PubMed: 18433157

"Quantitative phosphoproteomics of early elicitor signaling inArabidopsis.";
Benschop J.J., Mohammed S., O'Flaherty M., Heck A.J.R., Slijper M.,Menke F.L.H.;
Mol. Cell. Proteomics 6:1198-1214(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-586, AND MASSSPECTROMETRY.
PubMed: 17317660