| UniProt ID | UBC35_ARATH | |
|---|---|---|
| UniProt AC | Q94A97 | |
| Protein Name | Ubiquitin-conjugating enzyme E2 35 | |
| Gene Name | UBC35 | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 153 | |
| Subcellular Localization | ||
| Protein Description | Catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Required for postreplication repair of UV-damaged DNA and for adapting root developmental programs to suboptimal availability of iron.. | |
| Protein Sequence | MANSNLPRRIIKETQRLLSEPAPGISASPSEDNMRYFNVMILGPTQSPYEGGVFKLELFLPEEYPMAAPKVRFLTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLSENIAKHWKSNEAEAVDTAKEWTRLYASGA | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 4 | Phosphorylation | ----MANSNLPRRII ----CCCCCCCHHHH | 30.15 | 23572148 | |
| 19 | Phosphorylation | KETQRLLSEPAPGIS HHHHHHHCCCCCCCC | 46.24 | 30589143 | |
| 28 | Phosphorylation | PAPGISASPSEDNMR CCCCCCCCCCCCCCC | 23.36 | 25561503 | |
| 30 | Phosphorylation | PGISASPSEDNMRYF CCCCCCCCCCCCCCE | 55.90 | 25561503 | |
| 78 | Phosphorylation | VRFLTKIYHPNIDKL CCHHHCCCCCCHHHH | 16.87 | 19880383 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of UBC35_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of UBC35_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of UBC35_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| UEV1A_ARATH | MMZ1 | physical | 18178771 | |
| UEV1B_ARATH | MMZ2 | physical | 18178771 | |
| UEV1C_ARATH | MMZ3 | physical | 18178771 | |
| UEV1D_ARATH | UEV1D-4 | physical | 18178771 | |
| MMS2_YEAST | MMS2 | physical | 16786304 | |
| UB2V2_HUMAN | UBE2V2 | physical | 16786304 | |
| RGLG1_ARATH | RGLG1 | physical | 17586653 | |
| RGLG2_ARATH | RGLG2 | physical | 17586653 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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