TTC29_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TTC29_HUMAN
• UniProt AC: Q8NA56
• Protein Name: Tetratricopeptide repeat protein 29
• Gene Name: TTC29
• Organism: Homo sapiens (Human).
• Sequence Length: 475
• Protein Sequence: MTTLPPLPMTRPKLTALARQKLPCSSRKIPRSQLIKEKDDIDHYLEVNFKGLSKEEVAAYRNSYKKNICVDMLRDGYHKSFTELFALMERWDALREAARVRSLFWLQKPLEEQPDKLDYLYHYLTRAEDAERKESFEDVHNNLYALACYFNNSEDKWVRNHFYERCFKIAQLIKIDCGKKEAEAHMHMGLLYEEDGQLLEAAEHYEAFHQLTQGRIWKDETGRSLNLLACESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKEGSDKKMEAEASYYLGLAHLAAEEYETALTVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIKYLKKFVKIARNNFQSLDLVRASTMLGDIYNEKGYYNKASECFQQAFDTTVELMSMPLMDETKVHYGIAKAHQMMLTVNNYIESADLTSLNYLLSWKESRGNIEPDPVTEEFRGSTVEAVSQNSERLEELSRFPGDQKNET

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MTTLPPLPM ------CCCCCCCCC	36.72	26074081
3	Phosphorylation	-----MTTLPPLPMT -----CCCCCCCCCC	35.65	26074081
10	Phosphorylation	TLPPLPMTRPKLTAL CCCCCCCCHHHHHHH	41.71	26074081
15	Phosphorylation	PMTRPKLTALARQKL CCCHHHHHHHHHCCC	26.25	26074081
237	Phosphorylation	CESLLRTYRLLSDKM HHHHHHHHHHHCHHH	7.88	-
250	Phosphorylation	KMLENKEYKQAIKIL HHHCCHHHHHHHHHH	15.26	-
292	Phosphorylation	LAAEEYETALTVLDT HHHHHHHHHHHHHHH	26.51	23403867
299	Phosphorylation	TALTVLDTYCKISTD HHHHHHHHHHCCCCC	27.02	23403867
326	Phosphorylation	AIAKVLQSQGEMTEA HHHHHHHCCCCHHHH	35.67	21964256
331	O-linked_Glycosylation	LQSQGEMTEAIKYLK HHCCCCHHHHHHHHH	20.26	29351928
335	Acetylation	GEMTEAIKYLKKFVK CCHHHHHHHHHHHHH	52.13	25038526
383	Phosphorylation	CFQQAFDTTVELMSM HHHHHHHHHHHHHHC	26.70	26074081
384	Phosphorylation	FQQAFDTTVELMSMP HHHHHHHHHHHHHCC	17.52	26074081
411	Phosphorylation	KAHQMMLTVNNYIES HHHHHHHHHCCCHHH	11.86	23663014
415	Phosphorylation	MMLTVNNYIESADLT HHHHHCCCHHHCCCH	10.81	23663014
418	Phosphorylation	TVNNYIESADLTSLN HHCCCHHHCCCHHHH	19.95	23663014
422	Phosphorylation	YIESADLTSLNYLLS CHHHCCCHHHHHHHH	31.54	23663014
423	Phosphorylation	IESADLTSLNYLLSW HHHCCCHHHHHHHHH	23.16	23663014
426	Phosphorylation	ADLTSLNYLLSWKES CCCHHHHHHHHHHHH	17.82	23663014
429	Phosphorylation	TSLNYLLSWKESRGN HHHHHHHHHHHHCCC	33.24	23663014
449	Phosphorylation	VTEEFRGSTVEAVSQ CCHHHCCCCHHHHHC	25.64	20736484

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TTC29_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TTC29_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TTC29_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
LSG1_HUMAN	LSG1	physical	26186194
IF2P_HUMAN	EIF5B	physical	26186194
DHX16_HUMAN	DHX16	physical	26186194
ANFY1_HUMAN	ANKFY1	physical	26186194
OBSL1_HUMAN	OBSL1	physical	26186194
SPT6H_HUMAN	SUPT6H	physical	26186194
CDK18_HUMAN	CDK18	physical	26186194
FBXW8_HUMAN	FBXW8	physical	26186194
TBL1R_HUMAN	TBL1XR1	physical	26186194
IKIP_HUMAN	IKBIP	physical	26186194
MACF1_HUMAN	MACF1	physical	26186194
CSTF2_HUMAN	CSTF2	physical	26186194
NELFE_HUMAN	NELFE	physical	26186194
TAF8_HUMAN	TAF8	physical	26186194
CDK18_HUMAN	CDK18	physical	28514442
FBXW8_HUMAN	FBXW8	physical	28514442
SPT6H_HUMAN	SUPT6H	physical	28514442
DHX16_HUMAN	DHX16	physical	28514442
LSG1_HUMAN	LSG1	physical	28514442
TAF8_HUMAN	TAF8	physical	28514442
IKIP_HUMAN	IKBIP	physical	28514442
IF2P_HUMAN	EIF5B	physical	28514442
OBSL1_HUMAN	OBSL1	physical	28514442
PPIL4_HUMAN	PPIL4	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.