TGA2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TGA2_ARATH
• UniProt AC: P43273
• Protein Name: Transcription factor TGA2
• Gene Name: TGA2
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 330
• Subcellular Localization: Nucleus.
• Protein Description: Transcriptional activator that binds specifically to the DNA sequence 5'-TGACG-3'. Recognizes ocs elements like the as-1 motif of the cauliflower mosaic virus 35S promoter. Binding to the as-1-like cis elements mediate auxin- and salicylic acid-inducible transcription. Required to induce the systemic acquired resistance (SAR) via the regulation of pathogenesis-related genes expression. Binding to the as-1 element of PR-1 promoter is salicylic acid-inducible and mediated by NPR1. Could also bind to the C-boxes (5'-ATGACGTCAT-3') with high affinity..
• Protein Sequence: MADTSPRTDVSTDDDTDHPDLGSEGALVNTAASDSSDRSKGKMDQKTLRRLAQNREAARKSRLRKKAYVQQLENSRLKLTQLEQELQRARQQGVFISGTGDQAHSTGGNGALAFDAEHSRWLEEKNKQMNELRSALNAHAGDSELRIIVDGVMAHYEELFRIKSNAAKNDVFHLLSGMWKTPAERCFLWLGGFRSSELLKLLANQLEPMTERQLMGINNLQQTSQQAEDALSQGMESLQQSLADTLSSGTLGSSSSGNVASYMGQMAMAMGKLGTLEGFIRQADNLRLQTLQQMIRVLTTRQSARALLAIHDYFSRLRALSSLWLARPRE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Phosphorylation	MADTSPRTDVSTDDD CCCCCCCCCCCCCCC	44.10	30407730
11	Phosphorylation	TSPRTDVSTDDDTDH CCCCCCCCCCCCCCC	29.00	30407730
12	Phosphorylation	SPRTDVSTDDDTDHP CCCCCCCCCCCCCCC	43.21	30407730
16	Phosphorylation	DVSTDDDTDHPDLGS CCCCCCCCCCCCCCC	43.11	30407730
23	Phosphorylation	TDHPDLGSEGALVNT CCCCCCCCCCCCCCC	39.91	30407730

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TGA2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TGA2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TGA2_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NPR1_ARATH	NPR1	physical	12383081
NPR1_ARATH	NPR1	physical	18571510
NPR1_ARATH	NPR1	physical	12084833
NPR1_ARATH	NPR1	physical	15805484
GRXC8_ARATH	ROXY2	physical	21798944
GRXC7_ARATH	ROXY1	physical	22207719
GRXC8_ARATH	ROXY2	physical	22207719
GRS10_ARATH	AT3G21460	physical	22207719
GRC11_ARATH	AT3G62950	physical	22207719
GRC12_ARATH	AT2G47870	physical	22207719
GRS11_ARATH	AT1G06830	physical	22207719
GRXS9_ARATH	AT2G30540	physical	22207719
GRC14_ARATH	AT3G62960	physical	22207719
GRC13_ARATH	AT2G47880	physical	22207719
GRXS2_ARATH	AT5G18600	physical	22207719
GRXS3_ARATH	AT4G15700	physical	22207719
GRXS5_ARATH	AT4G15690	physical	22207719
GRXS1_ARATH	AT1G03020	physical	22207719
GRXS6_ARATH	AT3G62930	physical	22207719
GRS13_ARATH	AT1G03850	physical	22207719
GRC10_ARATH	AT5G11930	physical	22207719
GRXC6_ARATH	AT4G33040	physical	22207719
GRXC9_ARATH	GRX480	physical	22207719
NPR1_ARATH	NPR1	physical	25482810
SCL14_ARATH	SCL14	physical	18984675

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.