| UniProt ID | SRBS1_HUMAN | |
|---|---|---|
| UniProt AC | Q9BX66 | |
| Protein Name | Sorbin and SH3 domain-containing protein 1 | |
| Gene Name | SORBS1 {ECO:0000312|HGNC:HGNC:14565} | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 1292 | |
| Subcellular Localization | Cell junction, adherens junction. Cell membrane. Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Nucleus. Nucleus matrix. Colocalizes with the Ten-1 ICD form of TENM1 in the nucleus (By similarity). Colocalizes with actin stress fibers. Also | |
| Protein Description | Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions (By similarity).. | |
| Protein Sequence | MSSECDGGSKAVMNGLAPGSNGQDKATADPLRARSISAVKIIPVKTVKNASGLVLPTDMDLTKICTGKGAVTLRASSSYRETPSSSPASPQETRQHESKPGLEPEPSSADEWRLSSSADANGNAQPSSLAAKGYRSVHPNLPSDKSQDATSSSAAQPEVIVVPLYLVNTDRGQEGTARPPTPLGPLGCVPTIPATASAASPLTFPTLDDFIPPHLQRWPHHSQPARASGSFAPISQTPPSFSPPPPLVPPAPEDLRRVSEPDLTGAVSSTDSSPLLNEVSSSLIGTDSQAFPSVSKPSSAYPSTTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPTQEKPTSPGKAIEKRAKDDSRRVVKSTQDLSDVSMDEVGIPLRNTERSKDWYKTMFKQIHKLNRDTPEENPYFPTYKFPELPEIQQTSEEDNPYTPTYQFPASTPSPKSEDDDSDLYSPRYSFSEDTKSPLSVPRSKSEMSYIDGEKVVKRSATLPLPARSSSLKSSSERNDWEPPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSRDISPEEIDLKNEPWYKFFSELEFGKPPPKKIWDYTPGDCSILPREDRKTNLDKDLSLCQTELEADLEKMETLNKAPSANVPQSSAISPTPEISSETPGYIYSSNFHAVKRESDGAPGDLTSLENERQIYKSVLEGGDIPLQGLSGLKRPSSSASTKDSESPRHFIPADYLESTEEFIRRRHDDKEKLLADQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNIDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIELLPPAEKAQPKKLTPVQVLEYGEAIAKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVIKRPLVKNPVDYMDLPFSSSPSRSATASPQFSSHSKLITPAPSSLPHSRRALSPEMHAVTSEWISLTVGVPGRRSLALTPPLPPLPEASIYNTDHLALSPRASPSLSLSLPHLSWSDRPTPRSVASPLALPSPHKTYSLAPTSQASLHMNGDGGVHTPSSGIHQDSFLQLPLGSSDSVISQLSDAFSSQSKRQPWREESGQYERKAERGAGERGPGGPKISKKSCLKPSDVVRCLSTEQRLSDLNTPEESRPGKPLGSAFPGSEAEQTERHRGGEQAGRKAARRGGSQQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVKPLYL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 (in isoform 10) | Phosphorylation | - | 46.26 | 22210691 | |
| 2 (in isoform 12) | Phosphorylation | - | 46.26 | 22210691 | |
| 2 (in isoform 4) | Phosphorylation | - | 46.26 | 22210691 | |
| 2 (in isoform 7) | Phosphorylation | - | 46.26 | 22210691 | |
| 2 (in isoform 8) | Phosphorylation | - | 46.26 | 22210691 | |
| 3 (in isoform 10) | Phosphorylation | - | 54.85 | 22210691 | |
| 3 (in isoform 12) | Phosphorylation | - | 54.85 | 22210691 | |
| 3 (in isoform 4) | Phosphorylation | - | 54.85 | 22210691 | |
| 3 (in isoform 7) | Phosphorylation | - | 54.85 | 22210691 | |
| 3 (in isoform 8) | Phosphorylation | - | 54.85 | 22210691 | |
| 20 (in isoform 10) | Phosphorylation | - | 36.41 | 22210691 | |
| 20 (in isoform 12) | Phosphorylation | - | 36.41 | 22210691 | |
| 20 (in isoform 4) | Phosphorylation | - | 36.41 | 22210691 | |
| 20 (in isoform 7) | Phosphorylation | - | 36.41 | 22210691 | |
| 20 (in isoform 8) | Phosphorylation | - | 36.41 | 22210691 | |
| 35 | Phosphorylation | ADPLRARSISAVKII CCHHHHCCEEEEEEE | 21.65 | 26437602 | |
| 40 | Phosphorylation | ARSISAVKIIPVKTV HCCEEEEEEEECCCE | 34.33 | 24719451 | |
| 44 | Phosphorylation | SAVKIIPVKTVKNAS EEEEEEECCCEECCC | 5.98 | 24719451 | |
| 53 | Phosphorylation | TVKNASGLVLPTDMD CEECCCCCCCCCCCC | 3.11 | 24719451 | |
| 54 (in isoform 4) | Phosphorylation | - | 7.40 | 29116813 | |
| 54 (in isoform 7) | Phosphorylation | - | 7.40 | 29116813 | |
| 57 | Phosphorylation | ASGLVLPTDMDLTKI CCCCCCCCCCCCCHH | 39.53 | 22210691 | |
| 57 (in isoform 4) | Phosphorylation | - | 39.53 | 29507054 | |
| 57 (in isoform 7) | Phosphorylation | - | 39.53 | 29507054 | |
| 61 (in isoform 4) | Phosphorylation | - | 4.16 | 29116813 | |
| 61 (in isoform 7) | Phosphorylation | - | 4.16 | 29116813 | |
| 62 | Phosphorylation | LPTDMDLTKICTGKG CCCCCCCCHHCCCCC | 17.69 | 22210691 | |
| 72 | Phosphorylation | CTGKGAVTLRASSSY CCCCCCEEEEECCCC | 15.25 | 24719451 | |
| 74 (in isoform 4) | Phosphorylation | - | 24.06 | 26657352 | |
| 74 (in isoform 7) | Phosphorylation | - | 24.06 | 26657352 | |
| 75 (in isoform 4) | Phosphorylation | - | 19.51 | 26657352 | |
| 75 (in isoform 7) | Phosphorylation | - | 19.51 | 26657352 | |
| 76 | Phosphorylation | GAVTLRASSSYRETP CCEEEEECCCCCCCC | 17.24 | 26657352 | |
| 76 (in isoform 4) | Phosphorylation | - | 17.24 | 27251275 | |
| 76 (in isoform 7) | Phosphorylation | - | 17.24 | 27251275 | |
| 77 | Phosphorylation | AVTLRASSSYRETPS CEEEEECCCCCCCCC | 30.33 | 28857561 | |
| 78 | Phosphorylation | VTLRASSSYRETPSS EEEEECCCCCCCCCC | 26.22 | 26657352 | |
| 79 | Phosphorylation | TLRASSSYRETPSSS EEEECCCCCCCCCCC | 17.89 | 18669648 | |
| 79 (in isoform 3) | Phosphorylation | - | 17.89 | 18669648 | |
| 82 | Phosphorylation | ASSSYRETPSSSPAS ECCCCCCCCCCCCCC | 21.33 | 24972180 | |
| 82 (in isoform 3) | Phosphorylation | - | 21.33 | 18669648 | |
| 84 | Phosphorylation | SSYRETPSSSPASPQ CCCCCCCCCCCCCHH | 51.36 | 29255136 | |
| 85 | Phosphorylation | SYRETPSSSPASPQE CCCCCCCCCCCCHHH | 41.36 | 29255136 | |
| 85 (in isoform 3) | Phosphorylation | - | 41.36 | 18669648 | |
| 86 | Phosphorylation | YRETPSSSPASPQET CCCCCCCCCCCHHHH | 28.90 | 29255136 | |
| 86 (in isoform 3) | Phosphorylation | - | 28.90 | 18669648 | |
| 86 (in isoform 5) | Phosphorylation | - | 28.90 | 29116813 | |
| 86 (in isoform 6) | Phosphorylation | - | 28.90 | 29116813 | |
| 89 | Phosphorylation | TPSSSPASPQETRQH CCCCCCCCHHHHCCC | 30.42 | 19664994 | |
| 89 (in isoform 3) | Phosphorylation | - | 30.42 | 18669648 | |
| 89 (in isoform 5) | Phosphorylation | - | 30.42 | 29507054 | |
| 89 (in isoform 6) | Phosphorylation | - | 30.42 | 29507054 | |
| 93 | Phosphorylation | SPASPQETRQHESKP CCCCHHHHCCCCCCC | 30.31 | 29255136 | |
| 93 (in isoform 5) | Phosphorylation | - | 30.31 | 29116813 | |
| 93 (in isoform 6) | Phosphorylation | - | 30.31 | 29116813 | |
| 98 | Phosphorylation | QETRQHESKPGLEPE HHHCCCCCCCCCCCC | 41.86 | 22210691 | |
| 105 (in isoform 4) | Phosphorylation | - | 48.73 | 29507054 | |
| 106 (in isoform 5) | Phosphorylation | - | 44.28 | 26657352 | |
| 106 (in isoform 6) | Phosphorylation | - | 44.28 | 26657352 | |
| 107 (in isoform 5) | Phosphorylation | - | 36.17 | 26657352 | |
| 107 (in isoform 6) | Phosphorylation | - | 36.17 | 26657352 | |
| 108 (in isoform 4) | Phosphorylation | - | 50.91 | 26657352 | |
| 108 (in isoform 5) | Phosphorylation | - | 50.91 | 27251275 | |
| 108 (in isoform 6) | Phosphorylation | - | 50.91 | 27251275 | |
| 114 (in isoform 12) | Phosphorylation | - | 6.45 | 29507054 | |
| 114 (in isoform 8) | Phosphorylation | - | 6.45 | 29507054 | |
| 115 | Phosphorylation | SADEWRLSSSADANG CHHCCEECCCCCCCC | 17.42 | 26657352 | |
| 116 | Phosphorylation | ADEWRLSSSADANGN HHCCEECCCCCCCCC | 33.85 | 30266825 | |
| 117 | Phosphorylation | DEWRLSSSADANGNA HCCEECCCCCCCCCC | 27.13 | 26657352 | |
| 117 (in isoform 12) | Phosphorylation | - | 27.13 | 26657352 | |
| 117 (in isoform 8) | Phosphorylation | - | 27.13 | 26657352 | |
| 127 | Phosphorylation | ANGNAQPSSLAAKGY CCCCCCCCHHHHCCC | 26.38 | 30266825 | |
| 128 | Phosphorylation | NGNAQPSSLAAKGYR CCCCCCCHHHHCCCC | 28.80 | 30266825 | |
| 136 | Phosphorylation | LAAKGYRSVHPNLPS HHHCCCCCCCCCCCC | 19.12 | 28857561 | |
| 137 (in isoform 6) | Phosphorylation | - | 6.86 | 29507054 | |
| 140 (in isoform 6) | Phosphorylation | - | 50.10 | 26657352 | |
| 143 | Phosphorylation | SVHPNLPSDKSQDAT CCCCCCCCCCCCCCC | 61.92 | 28857561 | |
| 146 | Phosphorylation | PNLPSDKSQDATSSS CCCCCCCCCCCCCCC | 37.98 | 26657352 | |
| 146 (in isoform 9) | Phosphorylation | - | 37.98 | 29507054 | |
| 149 (in isoform 9) | Phosphorylation | - | 11.18 | 26657352 | |
| 150 | Phosphorylation | SDKSQDATSSSAAQP CCCCCCCCCCCCCCC | 37.11 | 30242111 | |
| 151 | Phosphorylation | DKSQDATSSSAAQPE CCCCCCCCCCCCCCC | 24.82 | 30242111 | |
| 152 | Phosphorylation | KSQDATSSSAAQPEV CCCCCCCCCCCCCCE | 21.46 | 30242111 | |
| 153 | Phosphorylation | SQDATSSSAAQPEVI CCCCCCCCCCCCCEE | 27.65 | 26657352 | |
| 181 | Phosphorylation | EGTARPPTPLGPLGC CCCCCCCCCCCCCCC | 33.55 | 27251275 | |
| 200 | Phosphorylation | PATASAASPLTFPTL CCCCCCCCCCCCCCH | 21.84 | 26657352 | |
| 203 | Phosphorylation | ASAASPLTFPTLDDF CCCCCCCCCCCHHHC | 30.84 | 24719451 | |
| 208 | Phosphorylation | PLTFPTLDDFIPPHL CCCCCCHHHCCCHHH | 51.78 | 24719451 | |
| 212 (in isoform 3) | Phosphorylation | - | 15.39 | 18669648 | |
| 228 | Phosphorylation | HSQPARASGSFAPIS CCCCCCCCCCCCCCC | 29.44 | 26657352 | |
| 230 | Phosphorylation | QPARASGSFAPISQT CCCCCCCCCCCCCCC | 18.75 | 29255136 | |
| 235 | Phosphorylation | SGSFAPISQTPPSFS CCCCCCCCCCCCCCC | 27.26 | 26657352 | |
| 237 | Phosphorylation | SFAPISQTPPSFSPP CCCCCCCCCCCCCCC | 30.31 | 26657352 | |
| 240 | Phosphorylation | PISQTPPSFSPPPPL CCCCCCCCCCCCCCC | 39.29 | 26657352 | |
| 242 | Phosphorylation | SQTPPSFSPPPPLVP CCCCCCCCCCCCCCC | 40.61 | 26657352 | |
| 246 (in isoform 12) | Phosphorylation | - | 52.33 | 27251275 | |
| 247 (in isoform 4) | Phosphorylation | - | 12.77 | 27251275 | |
| 249 (in isoform 12) | Phosphorylation | - | 27.33 | - | |
| 250 (in isoform 12) | Phosphorylation | - | 53.63 | 25159151 | |
| 250 (in isoform 4) | Phosphorylation | - | 53.63 | - | |
| 251 (in isoform 4) | Phosphorylation | - | 17.65 | 25159151 | |
| 254 (in isoform 12) | Phosphorylation | - | 44.40 | 29507054 | |
| 255 (in isoform 4) | Phosphorylation | - | 3.43 | 29507054 | |
| 256 (in isoform 12) | Phosphorylation | - | 49.64 | 28348404 | |
| 256 (in isoform 8) | Phosphorylation | - | 49.64 | 27251275 | |
| 257 (in isoform 4) | Phosphorylation | - | 43.54 | 28348404 | |
| 259 | Phosphorylation | PEDLRRVSEPDLTGA CHHHHCCCCCCCCCC | 41.42 | 26657352 | |
| 259 (in isoform 8) | Phosphorylation | - | 41.42 | - | |
| 260 (in isoform 8) | Phosphorylation | - | 39.72 | 25159151 | |
| 264 | Phosphorylation | RVSEPDLTGAVSSTD CCCCCCCCCCCCCCC | 30.40 | 24275569 | |
| 264 (in isoform 8) | Phosphorylation | - | 30.40 | 29507054 | |
| 266 (in isoform 8) | Phosphorylation | - | 7.87 | 28348404 | |
| 268 | Phosphorylation | PDLTGAVSSTDSSPL CCCCCCCCCCCCCHH | 27.30 | 26657352 | |
| 269 | Phosphorylation | DLTGAVSSTDSSPLL CCCCCCCCCCCCHHH | 29.63 | 26657352 | |
| 270 | Phosphorylation | LTGAVSSTDSSPLLN CCCCCCCCCCCHHHH | 32.18 | 24275569 | |
| 272 | Phosphorylation | GAVSSTDSSPLLNEV CCCCCCCCCHHHHHH | 33.66 | 24275569 | |
| 273 | Phosphorylation | AVSSTDSSPLLNEVS CCCCCCCCHHHHHHH | 23.52 | 26657352 | |
| 281 | Phosphorylation | PLLNEVSSSLIGTDS HHHHHHHHHHCCCCC | 34.05 | 19664995 | |
| 288 (in isoform 9) | Phosphorylation | - | 24.20 | 27251275 | |
| 291 (in isoform 9) | Phosphorylation | - | 3.43 | - | |
| 292 (in isoform 9) | Phosphorylation | - | 36.52 | 25159151 | |
| 293 | Phosphorylation | TDSQAFPSVSKPSSA CCCCCCCCCCCCCCC | 32.35 | 26091039 | |
| 294 | Phosphorylation | DSQAFPSVSKPSSAY CCCCCCCCCCCCCCC | 9.68 | 24719451 | |
| 296 (in isoform 9) | Phosphorylation | - | 46.92 | 29507054 | |
| 298 (in isoform 9) | Phosphorylation | - | 31.19 | 28348404 | |
| 299 | Phosphorylation | PSVSKPSSAYPSTTI CCCCCCCCCCCCCCC | 40.11 | 20068231 | |
| 303 | Phosphorylation | KPSSAYPSTTIVNPT CCCCCCCCCCCCCCC | 26.05 | 18669648 | |
| 318 | Phosphorylation | IVLLQHNREQQKRLS EEEEECCHHHHHHHH | 40.76 | 24719451 | |
| 323 | Methylation | HNREQQKRLSSLSDP CCHHHHHHHHCCCCH | 35.15 | 24396679 | |
| 325 | Phosphorylation | REQQKRLSSLSDPVS HHHHHHHHCCCCHHH | 33.01 | 30266825 | |
| 326 | Phosphorylation | EQQKRLSSLSDPVSE HHHHHHHCCCCHHHH | 36.16 | 30266825 | |
| 328 | Phosphorylation | QKRLSSLSDPVSERR HHHHHCCCCHHHHCC | 41.64 | 30266825 | |
| 332 | Phosphorylation | SSLSDPVSERRVGEQ HCCCCHHHHCCCCCC | 30.67 | 29255136 | |
| 338 | Phosphorylation | VSERRVGEQDSAPTQ HHHCCCCCCCCCCCC | 48.64 | 24719451 | |
| 341 | Phosphorylation | RRVGEQDSAPTQEKP CCCCCCCCCCCCCCC | 35.52 | 29255136 | |
| 342 | Phosphorylation | RVGEQDSAPTQEKPT CCCCCCCCCCCCCCC | 21.32 | 27251275 | |
| 342 (in isoform 3) | Phosphorylation | - | 21.32 | 27251275 | |
| 342 (in isoform 4) | Phosphorylation | - | 21.32 | 26657352 | |
| 343 (in isoform 4) | Phosphorylation | - | 38.27 | 29116813 | |
| 344 | Phosphorylation | GEQDSAPTQEKPTSP CCCCCCCCCCCCCCC | 49.42 | 29255136 | |
| 345 (in isoform 3) | Phosphorylation | - | 56.51 | - | |
| 346 | Phosphorylation | QDSAPTQEKPTSPGK CCCCCCCCCCCCCCH | 64.58 | 27251275 | |
| 346 (in isoform 3) | Phosphorylation | - | 64.58 | 25159151 | |
| 346 (in isoform 4) | Phosphorylation | - | 64.58 | 26657352 | |
| 348 (in isoform 4) | Phosphorylation | - | 37.04 | 26657352 | |
| 349 | Phosphorylation | APTQEKPTSPGKAIE CCCCCCCCCCCHHHH | 59.63 | 30266825 | |
| 350 | Phosphorylation | PTQEKPTSPGKAIEK CCCCCCCCCCHHHHH | 39.93 | 29255136 | |
| 350 (in isoform 3) | Phosphorylation | - | 39.93 | 29507054 | |
| 352 (in isoform 3) | Phosphorylation | - | 31.62 | 28348404 | |
| 352 (in isoform 4) | Phosphorylation | - | 31.62 | 27251275 | |
| 353 (in isoform 4) | Phosphorylation | - | 49.96 | 27251275 | |
| 355 (in isoform 4) | Phosphorylation | - | 7.95 | 27251275 | |
| 358 (in isoform 4) | Phosphorylation | - | 33.79 | 27251275 | |
| 363 | Phosphorylation | EKRAKDDSRRVVKST HHHCHHCCHHHHHHH | 31.92 | 22798277 | |
| 369 | Phosphorylation | DSRRVVKSTQDLSDV CCHHHHHHHCCHHHC | 21.49 | 26657352 | |
| 370 | Phosphorylation | SRRVVKSTQDLSDVS CHHHHHHHCCHHHCC | 22.00 | 26657352 | |
| 370 (in isoform 7) | Phosphorylation | - | 22.00 | 27251275 | |
| 373 (in isoform 7) | Phosphorylation | - | 3.19 | - | |
| 374 | Phosphorylation | VKSTQDLSDVSMDEV HHHHCCHHHCCHHHC | 44.23 | 30266825 | |
| 374 (in isoform 7) | Phosphorylation | - | 44.23 | 25159151 | |
| 377 | Phosphorylation | TQDLSDVSMDEVGIP HCCHHHCCHHHCCCC | 26.05 | 30266825 | |
| 378 (in isoform 7) | Phosphorylation | - | 5.24 | 29507054 | |
| 379 (in isoform 10) | Phosphorylation | - | 39.67 | 27251275 | |
| 380 (in isoform 7) | Phosphorylation | - | 33.72 | 28348404 | |
| 382 (in isoform 10) | Phosphorylation | - | 17.47 | - | |
| 383 (in isoform 10) | Phosphorylation | - | 3.33 | 25159151 | |
| 383 (in isoform 9) | Phosphorylation | - | 3.33 | 26657352 | |
| 384 (in isoform 9) | Phosphorylation | - | 21.24 | 29116813 | |
| 387 | Phosphorylation | EVGIPLRNTERSKDW HCCCCCCCCCCCHHH | 54.71 | 24719451 | |
| 387 (in isoform 10) | Phosphorylation | - | 54.71 | 29507054 | |
| 387 (in isoform 9) | Phosphorylation | - | 54.71 | 26657352 | |
| 388 | Phosphorylation | VGIPLRNTERSKDWY CCCCCCCCCCCHHHH | 26.75 | 23312004 | |
| 389 (in isoform 10) | Phosphorylation | - | 59.51 | 28348404 | |
| 389 (in isoform 9) | Phosphorylation | - | 59.51 | 26657352 | |
| 393 (in isoform 9) | Phosphorylation | - | 56.00 | 27251275 | |
| 394 | Phosphorylation | NTERSKDWYKTMFKQ CCCCCHHHHHHHHHH | 10.56 | 24719451 | |
| 394 (in isoform 9) | Phosphorylation | - | 10.56 | 27251275 | |
| 396 (in isoform 9) | Phosphorylation | - | 29.29 | 27251275 | |
| 399 (in isoform 9) | Phosphorylation | - | 6.79 | 27251275 | |
| 403 | Phosphorylation | KTMFKQIHKLNRDTP HHHHHHHHHHCCCCC | 26.51 | 24719451 | |
| 411 (in isoform 11) | Phosphorylation | - | 72.93 | 27251275 | |
| 414 (in isoform 11) | Phosphorylation | - | 35.11 | - | |
| 415 (in isoform 11) | Phosphorylation | - | 33.50 | 25159151 | |
| 419 | Phosphorylation | ENPYFPTYKFPELPE CCCCCCCCCCCCCCH | 15.74 | 24719451 | |
| 419 (in isoform 11) | Phosphorylation | - | 15.74 | 29507054 | |
| 421 (in isoform 11) | Phosphorylation | - | 3.91 | 28348404 | |
| 421 (in isoform 5) | Phosphorylation | - | 3.91 | 24076635 | |
| 422 (in isoform 5) | Phosphorylation | - | 37.75 | 24076635 | |
| 426 | Phosphorylation | YKFPELPEIQQTSEE CCCCCCCHHCCCCCC | 67.08 | 24719451 | |
| 431 | Phosphorylation | LPEIQQTSEEDNPYT CCHHCCCCCCCCCCC | 34.35 | 20068231 | |
| 431 (in isoform 2) | Phosphorylation | - | 34.35 | 25690035 | |
| 434 (in isoform 2) | Phosphorylation | - | 58.30 | 25690035 | |
| 435 (in isoform 5) | Phosphorylation | - | 34.45 | 29507054 | |
| 441 | Phosphorylation | DNPYTPTYQFPASTP CCCCCCCCCCCCCCC | 14.90 | 24719451 | |
| 447 | Phosphorylation | TYQFPASTPSPKSED CCCCCCCCCCCCCCC | 29.86 | 24719451 | |
| 448 (in isoform 6) | Phosphorylation | - | 46.25 | 26657352 | |
| 449 | Phosphorylation | QFPASTPSPKSEDDD CCCCCCCCCCCCCCC | 45.08 | 26657352 | |
| 452 | Phosphorylation | ASTPSPKSEDDDSDL CCCCCCCCCCCCCCC | 50.03 | 27499020 | |
| 452 (in isoform 6) | Phosphorylation | - | 50.03 | 26657352 | |
| 457 | Phosphorylation | PKSEDDDSDLYSPRY CCCCCCCCCCCCCCC | 36.19 | 27499020 | |
| 460 | Phosphorylation | EDDDSDLYSPRYSFS CCCCCCCCCCCCCCC | 22.94 | 21447384 | |
| 461 | Phosphorylation | DDDSDLYSPRYSFSE CCCCCCCCCCCCCCC | 15.36 | 26657352 | |
| 464 | Phosphorylation | SDLYSPRYSFSEDTK CCCCCCCCCCCCCCC | 19.90 | 26657352 | |
| 465 | Phosphorylation | DLYSPRYSFSEDTKS CCCCCCCCCCCCCCC | 24.47 | 29255136 | |
| 465 (in isoform 7) | Phosphorylation | - | 24.47 | 26657352 | |
| 466 (in isoform 7) | Phosphorylation | - | 7.41 | 29116813 | |
| 467 | Phosphorylation | YSPRYSFSEDTKSPL CCCCCCCCCCCCCCC | 28.73 | 25850435 | |
| 469 (in isoform 7) | Phosphorylation | - | 59.23 | 26657352 | |
| 470 | Phosphorylation | RYSFSEDTKSPLSVP CCCCCCCCCCCCCCC | 29.39 | 26657352 | |
| 471 (in isoform 7) | Phosphorylation | - | 63.50 | 26657352 | |
| 472 | Phosphorylation | SFSEDTKSPLSVPRS CCCCCCCCCCCCCCC | 32.92 | 26055452 | |
| 474 (in isoform 10) | Phosphorylation | - | 11.85 | 26657352 | |
| 475 | Phosphorylation | EDTKSPLSVPRSKSE CCCCCCCCCCCCCCC | 33.20 | 26055452 | |
| 475 (in isoform 10) | Phosphorylation | - | 33.20 | 29116813 | |
| 475 (in isoform 7) | Phosphorylation | - | 33.20 | 27251275 | |
| 476 (in isoform 7) | Phosphorylation | - | 6.34 | 27251275 | |
| 478 | Phosphorylation | KSPLSVPRSKSEMSY CCCCCCCCCCCCCCE | 55.34 | 27251275 | |
| 478 (in isoform 10) | Phosphorylation | - | 55.34 | 26657352 | |
| 478 (in isoform 7) | Phosphorylation | - | 55.34 | 27251275 | |
| 479 | O-linked_Glycosylation | SPLSVPRSKSEMSYI CCCCCCCCCCCCCEE | 34.17 | 30379171 | |
| 479 | Phosphorylation | SPLSVPRSKSEMSYI CCCCCCCCCCCCCEE | 34.17 | 26657352 | |
| 480 (in isoform 10) | Phosphorylation | - | 52.28 | 26657352 | |
| 481 | Phosphorylation | LSVPRSKSEMSYIDG CCCCCCCCCCCEECC | 39.52 | 21082442 | |
| 481 (in isoform 7) | Phosphorylation | - | 39.52 | 27251275 | |
| 484 | Phosphorylation | PRSKSEMSYIDGEKV CCCCCCCCEECCEEE | 18.19 | 26657352 | |
| 484 (in isoform 10) | Phosphorylation | - | 18.19 | 27251275 | |
| 485 | Phosphorylation | RSKSEMSYIDGEKVV CCCCCCCEECCEEEE | 11.17 | 21214269 | |
| 485 (in isoform 10) | Phosphorylation | - | 11.17 | 27251275 | |
| 487 (in isoform 10) | Phosphorylation | - | 51.47 | 27251275 | |
| 487 (in isoform 3) | Phosphorylation | - | 51.47 | 24275569 | |
| 490 (in isoform 10) | Phosphorylation | - | 58.83 | 27251275 | |
| 491 (in isoform 3) | Phosphorylation | - | 5.51 | 24275569 | |
| 493 | Phosphorylation | IDGEKVVKRSATLPL ECCEEEEEEEECCCC | 43.55 | 27251275 | |
| 495 | Phosphorylation | GEKVVKRSATLPLPA CEEEEEEEECCCCCC | 21.64 | 30266825 | |
| 497 | Phosphorylation | KVVKRSATLPLPARS EEEEEEECCCCCCCC | 30.10 | 30266825 | |
| 503 | Phosphorylation | ATLPLPARSSSLKSS ECCCCCCCCCCCCCC | 34.82 | 24719451 | |
| 504 | Phosphorylation | TLPLPARSSSLKSSS CCCCCCCCCCCCCCC | 26.78 | 24719451 | |
| 505 | Phosphorylation | LPLPARSSSLKSSSE CCCCCCCCCCCCCCC | 33.85 | 20068231 | |
| 506 | Phosphorylation | PLPARSSSLKSSSER CCCCCCCCCCCCCCC | 40.85 | 28857561 | |
| 509 | Phosphorylation | ARSSSLKSSSERNDW CCCCCCCCCCCCCCC | 44.37 | 20068231 | |
| 510 | Phosphorylation | RSSSLKSSSERNDWE CCCCCCCCCCCCCCC | 34.33 | 20068231 | |
| 511 | Phosphorylation | SSSLKSSSERNDWEP CCCCCCCCCCCCCCC | 47.90 | 20068231 | |
| 514 (in isoform 12) | Phosphorylation | - | 55.48 | 27135362 | |
| 521 (in isoform 12) | Phosphorylation | - | 61.54 | 27135362 | |
| 526 (in isoform 12) | Phosphorylation | - | 29.55 | 27135362 | |
| 534 | Phosphorylation | KYRAEPKSIYEYQPG CCCCCCCCEEECCCC | 40.91 | 27499020 | |
| 536 | Phosphorylation | RAEPKSIYEYQPGKS CCCCCCEEECCCCCC | 18.70 | 28796482 | |
| 536 (in isoform 12) | Phosphorylation | - | 18.70 | 28152594 | |
| 538 | Phosphorylation | EPKSIYEYQPGKSSV CCCCEEECCCCCCCC | 11.75 | - | |
| 543 | Phosphorylation | YEYQPGKSSVLTNEK EECCCCCCCCCCCCC | 31.43 | 24719451 | |
| 545 | Phosphorylation | YQPGKSSVLTNEKMS CCCCCCCCCCCCCCC | 11.17 | 24719451 | |
| 547 | Phosphorylation | PGKSSVLTNEKMSRD CCCCCCCCCCCCCCC | 38.89 | 27251275 | |
| 552 | Phosphorylation | VLTNEKMSRDISPEE CCCCCCCCCCCCHHH | 37.56 | 24670416 | |
| 556 | Phosphorylation | EKMSRDISPEEIDLK CCCCCCCCHHHHCCC | 30.46 | 29255136 | |
| 559 | Phosphorylation | SRDISPEEIDLKNEP CCCCCHHHHCCCCCH | 45.23 | 24719451 | |
| 564 | Phosphorylation | PEEIDLKNEPWYKFF HHHHCCCCCHHHHHH | 68.79 | 24719451 | |
| 587 (in isoform 4) | Phosphorylation | - | 10.39 | 22673903 | |
| 593 | Phosphorylation | DYTPGDCSILPREDR CCCCCCCCCCCHHHH | 31.72 | 20068231 | |
| 593 (in isoform 4) | Phosphorylation | - | 31.72 | 29116813 | |
| 594 (in isoform 12) | Phosphorylation | - | 8.47 | 22210691 | |
| 594 (in isoform 4) | Phosphorylation | - | 8.47 | 26657352 | |
| 595 (in isoform 12) | Phosphorylation | - | 1.56 | 22210691 | |
| 595 (in isoform 4) | Phosphorylation | - | 1.56 | 26657352 | |
| 597 (in isoform 12) | Phosphorylation | - | 55.81 | 22210691 | |
| 597 (in isoform 4) | Phosphorylation | - | 55.81 | 26657352 | |
| 599 (in isoform 12) | Phosphorylation | - | 59.67 | 22210691 | |
| 599 (in isoform 4) | Phosphorylation | - | 59.67 | 25159151 | |
| 601 (in isoform 4) | Phosphorylation | - | 54.83 | 30266825 | |
| 603 (in isoform 12) | Phosphorylation | - | 49.64 | 22210691 | |
| 603 (in isoform 4) | Phosphorylation | - | 49.64 | 30266825 | |
| 605 (in isoform 12) | Phosphorylation | - | 44.48 | 22210691 | |
| 606 (in isoform 12) | Phosphorylation | - | 64.83 | 22210691 | |
| 609 | Phosphorylation | TNLDKDLSLCQTELE CCCCHHHHHHHHHHH | 36.91 | 27251275 | |
| 630 | Phosphorylation | ETLNKAPSANVPQSS HHHHCCCCCCCCCCC | 37.02 | 23312004 | |
| 634 (in isoform 12) | Phosphorylation | - | 28.30 | 28978645 | |
| 636 | Phosphorylation | PSANVPQSSAISPTP CCCCCCCCCCCCCCC | 18.70 | 26437602 | |
| 637 | Phosphorylation | SANVPQSSAISPTPE CCCCCCCCCCCCCCC | 25.11 | 23312004 | |
| 640 | Phosphorylation | VPQSSAISPTPEISS CCCCCCCCCCCCCCC | 23.57 | 26657352 | |
| 642 | Phosphorylation | QSSAISPTPEISSET CCCCCCCCCCCCCCC | 27.11 | 26657352 | |
| 646 | Phosphorylation | ISPTPEISSETPGYI CCCCCCCCCCCCCEE | 22.06 | 23312004 | |
| 647 | Phosphorylation | SPTPEISSETPGYIY CCCCCCCCCCCCEEE | 51.67 | 23312004 | |
| 649 | Phosphorylation | TPEISSETPGYIYSS CCCCCCCCCCEEEEC | 24.78 | 23312004 | |
| 652 | Phosphorylation | ISSETPGYIYSSNFH CCCCCCCEEEECCEE | 9.63 | - | |
| 654 | Phosphorylation | SETPGYIYSSNFHAV CCCCCEEEECCEEEE | 9.50 | - | |
| 655 | Phosphorylation | ETPGYIYSSNFHAVK CCCCEEEECCEEEEE | 14.83 | 19664995 | |
| 665 | Phosphorylation | FHAVKRESDGAPGDL EEEEEECCCCCCCCC | 45.43 | 30266825 | |
| 673 | Phosphorylation | DGAPGDLTSLENERQ CCCCCCCHHHHHHHH | 35.69 | 26657352 | |
| 674 | Phosphorylation | GAPGDLTSLENERQI CCCCCCHHHHHHHHH | 40.77 | 26657352 | |
| 684 | Phosphorylation | NERQIYKSVLEGGDI HHHHHHHHHHCCCCC | 18.24 | 20068231 | |
| 684 (in isoform 9) | Phosphorylation | - | 18.24 | 22673903 | |
| 690 (in isoform 9) | Phosphorylation | - | 50.63 | 29116813 | |
| 691 (in isoform 9) | Phosphorylation | - | 4.08 | 26657352 | |
| 692 (in isoform 9) | Phosphorylation | - | 24.30 | 26657352 | |
| 694 (in isoform 9) | Phosphorylation | - | 45.48 | 26657352 | |
| 696 (in isoform 9) | Phosphorylation | - | 2.06 | 25159151 | |
| 697 | Phosphorylation | DIPLQGLSGLKRPSS CCCCCCCCCCCCCCC | 49.24 | 26657352 | |
| 697 (in isoform 12) | Phosphorylation | - | 49.24 | 25307156 | |
| 698 (in isoform 9) | Phosphorylation | - | 40.02 | 30266825 | |
| 700 (in isoform 12) | Phosphorylation | - | 66.83 | 25307156 | |
| 700 (in isoform 9) | Phosphorylation | - | 66.83 | 30266825 | |
| 703 | Phosphorylation | LSGLKRPSSSASTKD CCCCCCCCCCCCCCC | 40.74 | 26657352 | |
| 704 | Phosphorylation | SGLKRPSSSASTKDS CCCCCCCCCCCCCCC | 32.38 | 24972180 | |
| 705 | Phosphorylation | GLKRPSSSASTKDSE CCCCCCCCCCCCCCC | 30.49 | 24972180 | |
| 707 | Phosphorylation | KRPSSSASTKDSESP CCCCCCCCCCCCCCC | 37.63 | 24972180 | |
| 708 | O-linked_Glycosylation | RPSSSASTKDSESPR CCCCCCCCCCCCCCC | 38.29 | 30379171 | |
| 708 | Phosphorylation | RPSSSASTKDSESPR CCCCCCCCCCCCCCC | 38.29 | 24972180 | |
| 709 (in isoform 12) | Malonylation | - | 57.68 | 32601280 | |
| 710 (in isoform 12) | Phosphorylation | - | 58.69 | 24076635 | |
| 711 | Phosphorylation | SSASTKDSESPRHFI CCCCCCCCCCCCCCC | 41.34 | 29116813 | |
| 713 | Phosphorylation | ASTKDSESPRHFIPA CCCCCCCCCCCCCCH | 31.05 | 29802988 | |
| 714 (in isoform 8) | Phosphorylation | - | 29.70 | 22673903 | |
| 719 (in isoform 10) | Phosphorylation | - | 20.38 | 22673903 | |
| 720 (in isoform 8) | Phosphorylation | - | 17.17 | 29116813 | |
| 721 (in isoform 8) | Phosphorylation | - | 43.10 | 26657352 | |
| 722 | Phosphorylation | RHFIPADYLESTEEF CCCCCHHHHHCHHHH | 17.93 | - | |
| 722 (in isoform 8) | Phosphorylation | - | 17.93 | 26657352 | |
| 724 (in isoform 8) | Phosphorylation | - | 49.76 | 26657352 | |
| 725 | Phosphorylation | IPADYLESTEEFIRR CCHHHHHCHHHHHHH | 38.22 | 20068231 | |
| 725 (in isoform 10) | Phosphorylation | - | 38.22 | 29116813 | |
| 725 (in isoform 12) | Phosphorylation | - | 38.22 | 24076635 | |
| 726 | Phosphorylation | PADYLESTEEFIRRR CHHHHHCHHHHHHHH | 30.11 | 27251275 | |
| 726 (in isoform 10) | Phosphorylation | - | 30.11 | 26657352 | |
| 726 (in isoform 8) | Phosphorylation | - | 30.11 | 25159151 | |
| 727 | Phosphorylation | ADYLESTEEFIRRRH HHHHHCHHHHHHHHC | 61.25 | 27251275 | |
| 727 (in isoform 10) | Phosphorylation | - | 61.25 | 26657352 | |
| 728 (in isoform 8) | Phosphorylation | - | 46.60 | 30266825 | |
| 729 (in isoform 10) | Phosphorylation | - | 4.24 | 26657352 | |
| 730 (in isoform 8) | Phosphorylation | - | 3.66 | 30266825 | |
| 731 | Phosphorylation | ESTEEFIRRRHDDKE HCHHHHHHHHCHHHH | 34.60 | 27251275 | |
| 731 (in isoform 10) | Phosphorylation | - | 34.60 | 25159151 | |
| 733 (in isoform 10) | Phosphorylation | - | 27.95 | 30266825 | |
| 735 | Phosphorylation | EFIRRRHDDKEKLLA HHHHHHCHHHHHHHH | 67.85 | 24719451 | |
| 735 (in isoform 10) | Phosphorylation | - | 67.85 | 30266825 | |
| 749 (in isoform 6) | Phosphorylation | - | 56.26 | 22673903 | |
| 755 (in isoform 6) | Phosphorylation | - | 34.05 | 29116813 | |
| 756 (in isoform 6) | Phosphorylation | - | 4.10 | 26657352 | |
| 757 (in isoform 6) | Phosphorylation | - | 8.75 | 26657352 | |
| 759 (in isoform 6) | Phosphorylation | - | 23.14 | 26657352 | |
| 761 (in isoform 6) | Phosphorylation | - | 22.78 | 25159151 | |
| 763 (in isoform 6) | Phosphorylation | - | 14.83 | 30266825 | |
| 765 (in isoform 6) | Phosphorylation | - | 3.26 | 30266825 | |
| 786 | Phosphorylation | DLLNIDDTAKRKSGS HHCCCCHHHCCCCCC | 30.26 | 24076635 | |
| 791 | Phosphorylation | DDTAKRKSGSEMRPA CHHHCCCCCCCCCCC | 52.14 | 28348404 | |
| 793 | Phosphorylation | TAKRKSGSEMRPARA HHCCCCCCCCCCCHH | 35.00 | 28102081 | |
| 795 (in isoform 3) | Phosphorylation | - | 7.14 | 18669648 | |
| 796 (in isoform 3) | Phosphorylation | - | 20.06 | 29507054 | |
| 798 (in isoform 3) | Phosphorylation | - | 17.44 | 18669648 | |
| 800 | Phosphorylation | SEMRPARAKFDFKAQ CCCCCCHHHCCHHCC | 20.97 | 27251275 | |
| 800 (in isoform 3) | Phosphorylation | - | 20.97 | 26657352 | |
| 802 | Phosphorylation | MRPARAKFDFKAQTL CCCCHHHCCHHCCCH | 15.12 | 27251275 | |
| 802 (in isoform 3) | Phosphorylation | - | 15.12 | 24117733 | |
| 804 | Phosphorylation | PARAKFDFKAQTLKE CCHHHCCHHCCCHHH | 8.76 | 27251275 | |
| 804 (in isoform 3) | Phosphorylation | - | 8.76 | 26657352 | |
| 808 (in isoform 3) | Phosphorylation | - | 44.66 | 24117733 | |
| 811 (in isoform 3) | Phosphorylation | - | 59.75 | 27732954 | |
| 819 (in isoform 3) | Phosphorylation | - | 3.27 | - | |
| 821 (in isoform 3) | Phosphorylation | - | 10.00 | 29507054 | |
| 825 (in isoform 3) | Phosphorylation | - | 27.76 | - | |
| 831 | Phosphorylation | KQIDQNWYEGEHHGR EECCCCEECCCCCCC | 22.93 | - | |
| 862 | Phosphorylation | KAQPKKLTPVQVLEY HCCCCCCCCEEEEEC | 30.23 | 24972180 | |
| 887 | Phosphorylation | GDTQVEMSFRKGERI CCCEEEEEEECCCCE | 14.37 | 24719451 | |
| 895 | Phosphorylation | FRKGERITLLRQVDE EECCCCEEEEEECCC | 26.43 | 22210691 | |
| 905 | Phosphorylation | RQVDENWYEGRIPGT EECCCCCCCCCCCCC | 21.78 | 22210691 | |
| 907 (in isoform 5) | Phosphorylation | - | 19.68 | 22673903 | |
| 912 | Phosphorylation | YEGRIPGTSRQGIFP CCCCCCCCCCCCCCE | 18.51 | 20068231 | |
| 912 (in isoform 12) | Phosphorylation | - | 18.51 | 30177828 | |
| 913 | Phosphorylation | EGRIPGTSRQGIFPI CCCCCCCCCCCCCEE | 28.64 | 20068231 | |
| 913 (in isoform 12) | Phosphorylation | - | 28.64 | 27499020 | |
| 913 (in isoform 5) | Phosphorylation | - | 28.64 | 29116813 | |
| 914 (in isoform 5) | Phosphorylation | - | 38.28 | 26657352 | |
| 915 (in isoform 5) | Phosphorylation | - | 49.45 | 26657352 | |
| 916 (in isoform 12) | Phosphorylation | - | 23.53 | 27499020 | |
| 917 (in isoform 5) | Phosphorylation | - | 2.55 | 26657352 | |
| 919 (in isoform 5) | Phosphorylation | - | 18.98 | 25159151 | |
| 921 | Phosphorylation | RQGIFPITYVDVIKR CCCCCEEEEEECCCC | 20.10 | 20068231 | |
| 921 (in isoform 5) | Phosphorylation | - | 20.10 | 30266825 | |
| 922 | Phosphorylation | QGIFPITYVDVIKRP CCCCEEEEEECCCCC | 8.72 | 20068231 | |
| 923 (in isoform 5) | Phosphorylation | - | 3.38 | 30266825 | |
| 937 | Phosphorylation | LVKNPVDYMDLPFSS CCCCCCCCCCCCCCC | 7.86 | 30576142 | |
| 943 | O-linked_Glycosylation | DYMDLPFSSSPSRSA CCCCCCCCCCCCCCC | 28.15 | 30379171 | |
| 943 | Phosphorylation | DYMDLPFSSSPSRSA CCCCCCCCCCCCCCC | 28.15 | 29255136 | |
| 944 | Phosphorylation | YMDLPFSSSPSRSAT CCCCCCCCCCCCCCC | 46.80 | 29255136 | |
| 945 | Phosphorylation | MDLPFSSSPSRSATA CCCCCCCCCCCCCCC | 26.20 | 29255136 | |
| 947 | Phosphorylation | LPFSSSPSRSATASP CCCCCCCCCCCCCCC | 40.59 | 29255136 | |
| 949 | Phosphorylation | FSSSPSRSATASPQF CCCCCCCCCCCCCCC | 34.02 | 26437602 | |
| 951 | Phosphorylation | SSPSRSATASPQFSS CCCCCCCCCCCCCCC | 28.99 | 22673903 | |
| 953 | Phosphorylation | PSRSATASPQFSSHS CCCCCCCCCCCCCCC | 18.19 | 18669648 | |
| 957 | Phosphorylation | ATASPQFSSHSKLIT CCCCCCCCCCCCCCC | 23.15 | 22673903 | |
| 958 | Phosphorylation | TASPQFSSHSKLITP CCCCCCCCCCCCCCC | 32.82 | 22673903 | |
| 973 (in isoform 12) | Phosphorylation | - | 22.86 | 25307156 | |
| 1004 | Phosphorylation | GRRSLALTPPLPPLP CCCCEECCCCCCCCC | 19.77 | 22673903 | |
| 1014 | Phosphorylation | LPPLPEASIYNTDHL CCCCCCCCCCCCCCC | 24.76 | 22673903 | |
| 1018 | Phosphorylation | PEASIYNTDHLALSP CCCCCCCCCCCCCCC | 14.07 | 22673903 | |
| 1024 | Phosphorylation | NTDHLALSPRASPSL CCCCCCCCCCCCCCC | 13.51 | 21815630 | |
| 1034 | Phosphorylation | ASPSLSLSLPHLSWS CCCCCCEECCCCCCC | 36.16 | 26437602 | |
| 1045 | Phosphorylation | LSWSDRPTPRSVASP CCCCCCCCCCCCCCC | 32.03 | - | |
| 1048 | O-linked_Glycosylation | SDRPTPRSVASPLAL CCCCCCCCCCCCCCC | 24.20 | 30379171 | |
| 1048 | Phosphorylation | SDRPTPRSVASPLAL CCCCCCCCCCCCCCC | 24.20 | 26437602 | |
| 1051 | Phosphorylation | PTPRSVASPLALPSP CCCCCCCCCCCCCCC | 20.49 | 26437602 | |
| 1124 | Phosphorylation | RQPWREESGQYERKA CCCHHHHHCHHHHHH | 26.83 | - | |
| 1127 | Phosphorylation | WREESGQYERKAERG HHHHHCHHHHHHHCC | 22.64 | - | |
| 1130 | Acetylation | ESGQYERKAERGAGE HHCHHHHHHHCCCCC | 42.53 | 20167786 | |
| 1146 | Phosphorylation | GPGGPKISKKSCLKP CCCCCCCCHHHCCCH | 39.91 | 26437602 | |
| 1161 | Phosphorylation | SDVVRCLSTEQRLSD HHHHHHCCHHHHHHH | 33.26 | 26437602 | |
| 1166 (in isoform 11) | Phosphorylation | - | 4.70 | 26437602 | |
| 1167 | Phosphorylation | LSTEQRLSDLNTPEE CCHHHHHHHCCCCCC | 42.09 | - | |
| 1169 (in isoform 11) | Phosphorylation | - | 7.45 | 24043423 | |
| 1172 (in isoform 11) | Phosphorylation | - | 42.14 | 24043423 | |
| 1180 (in isoform 11) | Phosphorylation | - | 48.12 | 20071362 | |
| 1182 (in isoform 11) | Phosphorylation | - | 26.00 | 29507054 | |
| 1183 | Phosphorylation | RPGKPLGSAFPGSEA CCCCCCCCCCCCCHH | 34.13 | - | |
| 1186 (in isoform 11) | Phosphorylation | - | 45.15 | - | |
| 1193 | Phosphorylation | PGSEAEQTERHRGGE CCCHHHHHHHHCCHH | 26.88 | - | |
| 1197 (in isoform 12) | Phosphorylation | - | 62.12 | 22673903 | |
| 1203 (in isoform 12) | Phosphorylation | - | 31.17 | 29116813 | |
| 1204 (in isoform 12) | Phosphorylation | - | 28.58 | 26657352 | |
| 1205 (in isoform 12) | Phosphorylation | - | 45.54 | 26657352 | |
| 1207 (in isoform 12) | Phosphorylation | - | 12.53 | 26657352 | |
| 1209 (in isoform 12) | Phosphorylation | - | 49.45 | 25159151 | |
| 1211 (in isoform 12) | Phosphorylation | - | 22.07 | 30266825 | |
| 1213 (in isoform 12) | Phosphorylation | - | 63.35 | 30266825 | |
| 1223 | Phosphorylation | QAQQRRVTPDRSQTS HHHHHCCCCCCHHHH | 20.05 | 26091039 | |
| 1227 | Phosphorylation | RRVTPDRSQTSQDLF HCCCCCCHHHHHHHH | 45.23 | 29802988 | |
| 1229 | Phosphorylation | VTPDRSQTSQDLFSY CCCCCHHHHHHHHHH | 29.60 | 26657352 | |
| 1230 | Phosphorylation | TPDRSQTSQDLFSYQ CCCCHHHHHHHHHHH | 17.66 | 26657352 | |
| 1236 | Phosphorylation | TSQDLFSYQALYSYI HHHHHHHHHHHHHHC | 7.17 | 22798277 | |
| 1240 | Phosphorylation | LFSYQALYSYIPQND HHHHHHHHHHCCCCC | 11.48 | 21082442 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
| 326 | Y | Phosphorylation | Kinase | SRC | P12931 | GPS |
| 326 | Y | Phosphorylation | Kinase | ABL-FAMILY | - | GPS |
| 360 | Y | Phosphorylation | Kinase | SRC | P12931 | GPS |
| 360 | Y | Phosphorylation | Kinase | ABL-FAMILY | - | GPS |
| 536 | Y | Phosphorylation | Kinase | ABL1 | P00519 | Uniprot |
| 632 | Y | Phosphorylation | Kinase | ABL-FAMILY | - | GPS |
| 654 | Y | Phosphorylation | Kinase | ABL1 | P00519 | Uniprot |
| 1240 | Y | Phosphorylation | Kinase | ABL1 | P00519 | Uniprot |
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SRBS1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SRBS1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| INSM1_HUMAN | INSM1 | physical | 12079283 | |
| CBL_HUMAN | CBL | physical | 15128873 | |
| VINC_HUMAN | VCL | physical | 10085297 | |
| SHIP2_HUMAN | INPPL1 | physical | 12504111 | |
| FLOT1_HUMAN | FLOT1 | physical | 11001060 | |
| ABL1_HUMAN | ABL1 | physical | 11374898 | |
| SEM6A_HUMAN | SEMA6A | physical | 12421765 | |
| VINC_HUMAN | VCL | physical | 12765336 | |
| FLOT1_HUMAN | FLOT1 | physical | 15939299 | |
| ABL1_HUMAN | ABL1 | physical | 19891780 | |
| FRS2_HUMAN | FRS2 | physical | 22235335 | |
| SH2B2_HUMAN | SH2B2 | physical | 15031295 | |
| NCK2_HUMAN | NCK2 | physical | 11557983 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
| Phosphorylation | |
| Reference | PubMed |
| "Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-89, AND MASSSPECTROMETRY. | |
| "A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-79; SER-86; SER-89;SER-472; SER-665; THR-862; SER-945 AND SER-953, AND MASS SPECTROMETRY. | |
