SR43C_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SR43C_ARATH
• UniProt AC: O22265
• Protein Name: Signal recognition particle 43 kDa protein, chloroplastic
• Gene Name: CAO
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 373
• Subcellular Localization: Plastid, chloroplast stroma .
• Protein Description: Component of the chloroplast signal recognition particle pathway. Required for post-translational targeting of proteins into the thylakoid membrane but seems to be dispensable for co-translational targeting with a translating ribosome present. May be able to function independently of cpFTSY and FFC/cpSRP54 in targeting LHCPs to the thylakoids. Acts as a highly specific chaperone for LHCPs, preventing aggregation and being able to dissolve aggregates..
• Protein Sequence: MQKVFLAMDTCALVIHQSLSRIKLSPPKSSSSSSSAFSPESLPIRRIELCFRGAICAAVQRNYEETTSSVEEAEEDDESSSSYGEVNKIIGSRTAGEGAMEYLIEWKDGHSPSWVPSSYIAADVVSEYETPWWTAARKADEQALSQLLEDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDHRDMRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELAREILKTTPKGNPMQFGRRIGLEKVINVLEGQVFEYAEVDEIVEKRGKGKDVEYLVRWKDGGDCEWVKGVHVAEDVAKDYEDGLEYAVAESVIGKRVGDDGKTIEYLVKWTDMSDATWEPQDNVDSTLVLLYQQQQPMNE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
32	Phosphorylation	SPPKSSSSSSSAFSP CCCCCCCCCCCCCCC	35.87	29654922
145	Phosphorylation	KADEQALSQLLEDRD HHHHHHHHHHHHCCC	23.07	27545962

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SR43C_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SR43C_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SR43C_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SR54C_ARATH	CPSRP54	physical	18586266
ALB3_ARATH	ALB3	physical	21832051
HS23M_ARATH	HSP23.6-MITO	physical	21798944
TOE2_ARATH	TOE2	physical	21798944
BH027_ARATH	AT4G29930	physical	21798944
TCP13_ARATH	PTF1	physical	21798944
TCP14_ARATH	TCP14	physical	21798944
Y4193_ARATH	AT4G10930	physical	21798944
SR54C_ARATH	CPSRP54	physical	20018841
SR43C_ARATH	CAO	physical	17513500
ALB3_ARATH	ALB3	physical	17513500
SR543_ARATH	AT1G48900	physical	25833951
SR43C_ARATH	CAO	physical	10480939
SR54C_ARATH	CPSRP54	physical	10480939

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.