dbPTM

SNAI3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SNAI3_HUMAN
UniProt AC	Q3KNW1
Protein Name	Zinc finger protein SNAI3
Gene Name	SNAI3
Organism	Homo sapiens (Human).
Sequence Length	292
Subcellular Localization	Nucleus.
Protein Description	Seems to inhibit myoblast differentiation. Transcriptional repressor of E-box-dependent transactivation of downstream myogenic bHLHs genes. Binds preferentially to the canonical E-box sequences 5'-CAGGTG-3' and 5'-CACCTG-3' (By similarity)..
Protein Sequence	MPRSFLVKTHSSHRVPNYRRLETQREINGACSACGGLVVPLLPRDKEAPSVPGDLPQPWDRSSAVACISLPLLPRIEEALGASGLDALEVSEVDPRASRAAIVPLKDSLNHLNLPPLLVLPTRWSPTLGPDRHGAPEKLLGAERMPRAPGGFECFHCHKPYHTLAGLARHRQLHCHLQVGRVFTCKYCDKEYTSLGALKMHIRTHTLPCTCKICGKAFSRPWLLQGHVRTHTGEKPYACSHCSRAFADRSNLRAHLQTHSDAKKYRCRRCTKTFSRMSLLARHEESGCCPGP

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
230	Phosphorylation	LLQGHVRTHTGEKPY EEEEEEEECCCCCCE	23.77	-
232	Phosphorylation	QGHVRTHTGEKPYAC EEEEEECCCCCCEEC	46.56	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SNAI3_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SNAI3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SNAI3_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HDAC2_HUMAN	HDAC2	physical	14673164
HDAC1_HUMAN	HDAC1	physical	14673164
SIN3A_MOUSE	Sin3a	physical	14673164
STRN3_HUMAN	STRN3	physical	26186194
ZO2_HUMAN	TJP2	physical	26186194
STRP1_HUMAN	STRIP1	physical	26186194
ZO2_HUMAN	TJP2	physical	28514442
STRN3_HUMAN	STRN3	physical	28514442

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SNAI3_HUMAN

Related Literatures of Post-Translational Modification