SERF2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SERF2_HUMAN
• UniProt AC: P84101
• Protein Name: Small EDRK-rich factor 2
• Gene Name: SERF2
• Organism: Homo sapiens (Human).
• Sequence Length: 59
• Protein Sequence: MTRGNQRELARQKNMKKQSDSVKGKRRDDGLSAAARKQRDSEIMQQKQKKANEKKEEPK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Methylation	-----MTRGNQRELA -----CCHHHHHHHH	40.54	115916477
19	Phosphorylation	QKNMKKQSDSVKGKR HHHHHHHHHHHCCCC	40.51	26074081
21	Phosphorylation	NMKKQSDSVKGKRRD HHHHHHHHHCCCCHH	30.86	26657352
23	Ubiquitination	KKQSDSVKGKRRDDG HHHHHHHCCCCHHHH	63.77	33845483
32	Phosphorylation	KRRDDGLSAAARKQR CCHHHHHHHHHHHHH	22.76	26074081
33	Ubiquitination	RRDDGLSAAARKQRD CHHHHHHHHHHHHHH	15.35	32015554
36	Ubiquitination	DGLSAAARKQRDSEI HHHHHHHHHHHHHHH	30.80	24816145
41	Phosphorylation	AARKQRDSEIMQQKQ HHHHHHHHHHHHHHH	31.07	25159151
44	Sulfoxidation	KQRDSEIMQQKQKKA HHHHHHHHHHHHHHH	2.79	30846556
47	Ubiquitination	DSEIMQQKQKKANEK HHHHHHHHHHHHHHH	47.39	32015554
47	Acetylation	DSEIMQQKQKKANEK HHHHHHHHHHHHHHH	47.39	25953088
49	Ubiquitination	EIMQQKQKKANEKKE HHHHHHHHHHHHHCC	61.97	-
50	Ubiquitination	IMQQKQKKANEKKEE HHHHHHHHHHHHCCC	54.68	24816145
54	Acetylation	KQKKANEKKEEPK-- HHHHHHHHCCCCC--	66.35	30592321

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SERF2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SERF2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SERF2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RHXF2_HUMAN	RHOXF2	physical	16189514
PSME3_HUMAN	PSME3	physical	16189514
RBPMS_HUMAN	RBPMS	physical	16189514
CHD3_HUMAN	CHD3	physical	16169070
THAP1_HUMAN	THAP1	physical	25416956
BOLL_HUMAN	BOLL	physical	25416956
KR103_HUMAN	KRTAP10-3	physical	25416956

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.