| UniProt ID | SBIR1_ARATH | |
|---|---|---|
| UniProt AC | Q9SKB2 | |
| Protein Name | Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 | |
| Gene Name | SOBIR1 | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 641 | |
| Subcellular Localization |
Cell membrane Single-pass type I membrane protein . |
|
| Protein Description | Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Acting as a counterplayer of BIR1, promotes the activation of plant defense and cell death. [PubMed: 19616764 Component of the RLP23-SOBIR1-BAK1 complex that mediates NLP-triggered immunity] | |
| Protein Sequence | MAVPTGSANLFLRPLILAVLSFLLLSSFVSSVEWLDIDSSDLKALQVIETELGVNSQRSSASDVNPCGRRGVFCERRHSATTGEYVLRVTRLVYRSRSLTGTISPVIGMLSELKELTLSNNQLVNAVPVDILSCKQLEVLDLRKNRFSGQIPGNFSSLSRLRILDLSSNKLSGNLNFLKNLRNLENLSVANNLFSGKIPEQIVSFHNLRFFDFSGNRYLEGPAPVMSSIKLQTSPHQTRHILAETPTSSPTNKPNNSTTSKAPKGAPKPGKLKKKKKKSKKKKVAAWILGFVVGAIGGTISGFVFSVLFKLIIQAIRGSEKPPGPSIFSPLIKKAEDLAFLENEEALASLEIIGRGGCGEVFKAELPGSNGKIIAVKKVIQPPKDADELTDEDSKFLNKKMRQIRSEINTVGHIRHRNLLPLLAHVSRPECHYLVYEYMEKGSLQDILTDVQAGNQELMWPARHKIALGIAAGLEYLHMDHNPRIIHRDLKPANVLLDDDMEARISDFGLAKAMPDAVTHITTSHVAGTVGYIAPEFYQTHKFTDKCDIYSFGVILGILVIGKLPSDEFFQHTDEMSLIKWMRNIITSENPSLAIDPKLMDQGFDEQMLLVLKIACYCTLDDPKQRPNSKDVRTMLSQIKH | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 154 | N-linked_Glycosylation | FSGQIPGNFSSLSRL CCCCCCCCCCCCCCE | 28.42 | - | |
| 186 | N-linked_Glycosylation | KNLRNLENLSVANNL HHHHHHCCCHHHHCH | 40.56 | - | |
| 256 | N-linked_Glycosylation | SPTNKPNNSTTSKAP CCCCCCCCCCCCCCC | 49.62 | - | |
| 390 | Phosphorylation | PKDADELTDEDSKFL CCCHHHCCHHHHHHH | 34.98 | 19880383 | |
| 394 | Phosphorylation | DELTDEDSKFLNKKM HHCCHHHHHHHHHHH | 24.22 | 30407730 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SBIR1_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SBIR1_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SBIR1_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| RLK5_ARATH | HAE | physical | 21423366 | |
| HHP2_ARATH | HHP2 | physical | 24833385 | |
| HHP4_ARATH | HHP4 | physical | 24833385 | |
| UBC34_ARATH | UBC34 | physical | 24833385 | |
| CNIH1_ARATH | AT3G12180 | physical | 24833385 | |
| CP21D_ARATH | AT3G66654 | physical | 24833385 | |
| PAM74_ARATH | AT5G59650 | physical | 24833385 | |
| WAK3_ARATH | WAK3 | physical | 24833385 | |
| BETL2_ARATH | AT1G29060 | physical | 24833385 | |
| BET12_ARATH | ATBET12 | physical | 24833385 | |
| VAP21_ARATH | AT5G47180 | physical | 24833385 | |
| BAK1_ARATH | BAK1 | genetic | 25944825 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
