UniProt ID | S38A6_HUMAN | |
---|---|---|
UniProt AC | Q8IZM9 | |
Protein Name | Probable sodium-coupled neutral amino acid transporter 6 | |
Gene Name | SLC38A6 | |
Organism | Homo sapiens (Human). | |
Sequence Length | 456 | |
Subcellular Localization |
Cell membrane Multi-pass membrane protein . Colocalizes with synaptotagmins and SNAP25. |
|
Protein Description | Probable sodium-dependent amino acid/proton antiporter, could be a neuronal transporter for glutamate.. | |
Protein Sequence | MEASWGSFNAERGWYVSVQQPEEAEAEELSPLLSNELHRQRSPGVSFGLSVFNLMNAIMGSGILGLAYVLANTGVFGFSFLLLTVALLASYSVHLLLSMCIQTAVTSYEDLGLFAFGLPGKLVVAGTIIIQNIGAMSSYLLIIKTELPAAIAEFLTGDYSRYWYLDGQTLLIIICVGIVFPLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLTLNYVEKGFQISNVTDDCKPKLFHFSKESAYALPTMAFSFLCHTSILPIYCELQSPSKKRMQNVTNTAIALSFLIYFISALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFFSNFPFSWIRHFLITLALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIFIFPGLFYLKLSREDFLSWKKLGAFVLLIFGILVGNFSLALIIFDWINK | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
1 | Acetylation | -------MEASWGSF -------CCCCCCCC | 9.78 | 20068231 | |
4 | Phosphorylation | ----MEASWGSFNAE ----CCCCCCCCCCC | 20.75 | 20068231 | |
7 | Phosphorylation | -MEASWGSFNAERGW -CCCCCCCCCCCCCE | 14.74 | 20068231 | |
233 | N-linked_Glycosylation | EKGFQISNVTDDCKP HCCEEEECCCCCCCC | 42.19 | UniProtKB CARBOHYD | |
283 | N-linked_Glycosylation | PSKKRMQNVTNTAIA CCHHHHCHHHHHHHH | 32.98 | UniProtKB CARBOHYD | |
299 | Phosphorylation | SFLIYFISALFGYLT HHHHHHHHHHHHHHH | 14.71 | 22210691 | |
304 | Phosphorylation | FISALFGYLTFYDKV HHHHHHHHHHHHHHH | 8.67 | 22210691 | |
306 | Phosphorylation | SALFGYLTFYDKVES HHHHHHHHHHHHHHH | 16.21 | 22210691 | |
322 | Phosphorylation | LLKGYSKYLSHDVVV HHHHHHHHCCCCHHH | 13.90 | 29759185 | |
435 (in isoform 2) | Phosphorylation | - | 2.28 | - | |
473 (in isoform 2) | Phosphorylation | - | - | ||
478 (in isoform 2) | Phosphorylation | - | - |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of S38A6_HUMAN !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of S38A6_HUMAN !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of S38A6_HUMAN !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
TRFE_HUMAN | TF | physical | 26186194 | |
NPL4_HUMAN | NPLOC4 | physical | 26186194 | |
MUCL1_HUMAN | MUCL1 | physical | 26186194 | |
APOB_HUMAN | APOB | physical | 26186194 | |
MTCH2_HUMAN | MTCH2 | physical | 26186194 | |
ZG16B_HUMAN | ZG16B | physical | 26186194 | |
CYB5_HUMAN | CYB5A | physical | 26186194 | |
RFOX3_HUMAN | RBFOX3 | physical | 26186194 | |
TRFE_HUMAN | TF | physical | 28514442 |
Kegg Disease | ||||||
---|---|---|---|---|---|---|
There are no disease associations of PTM sites. | ||||||
OMIM Disease | ||||||
There are no disease associations of PTM sites. | ||||||
Kegg Drug | ||||||
There are no disease associations of PTM sites. | ||||||
DrugBank | ||||||
There are no disease associations of PTM sites. |
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