RLF2_SCHPO - dbPTM
RLF2_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RLF2_SCHPO
UniProt AC Q1MTN9
Protein Name Chromatin assembly factor 1 subunit rlf2
Gene Name rlf2
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 544
Subcellular Localization Nucleus .
Protein Description Acts as a component of chromatin assembly factor 1 (CAF-1), which assembles histone octamers onto replicating DNA in vitro. It performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. May facilitate the efficient and timely assembly of histones into telomeric chromatin (By similarity)..
Protein Sequence MNSESVDSDVAASTSNKGNELCSSSTDITSLSVSSPNESVIHSSHSASEADEYVCKLSYEGNRKKRIYNGSAEAGKEKKLQKQRAQEERIRQKEAERLKREKERQQREQEKKLREQEKIAAKKMKELEKLEKERIRLQEQQRRKEERDQKLREKEEAQRLRQEQILNKERQQLKLNNFFTKGVEKRIAPNENFVADKTDELNEFEKEFRPFFIKHQMSLSKYPSPNESDSFLDEVLSTSKSYPLKLNDIFTPSDAVSSANSLGVSNRNSENEVRQLMSAYQDPSVSKPQEILSCLSQIPIKFIFFYQDVRPPYFGSYTKTHSHGSNVLLNPWLEDEDIDYTYDSEAEWVADEEDDGEDLESEDEEVDNSDDIVEDGDNAFVDDEDDDKDSVNASNTHRSSGPLEVIVEGPVWDSKFLPDFNCLSLIEPISSFSASTYLQIDPKEDLWASQDTAPASSGMTIGPTSSLSDDLQVRFPSEDIPKFIEYVRNSHDNKVFLIENLRHMFPYVTKNIISETLGKVAVRKGKSVSDGWIIKENFASLLSS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of RLF2_SCHPO !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RLF2_SCHPO !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RLF2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RLF2_SCHPO !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
POB3_SCHPOpob3genetic
19547744
CDS1_SCHPOcds1genetic
24478943
SRS2_SCHPOsrs2genetic
25313826
HUS2_SCHPOrqh1genetic
25313826
HUS2_SCHPOrqh1physical
25313826
YEG3_SCHPOpcf2physical
25313826
PCNA_SCHPOpcn1physical
25313826

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RLF2_SCHPO

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Related Literatures of Post-Translational Modification

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