dbPTM

RIPP2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RIPP2_HUMAN
UniProt AC	Q5TAB7
Protein Name	Protein ripply2
Gene Name	RIPPLY2
Organism	Homo sapiens (Human).
Sequence Length	128
Subcellular Localization	Nucleus .
Protein Description	Plays a role in somitogenesis. Required for somite segregation and establishment of rostrocaudal polarity in somites (By similarity)..
Protein Sequence	MENAGGAEGTESGAAACAATDGPTRRAGADSGYAGFWRPWVDAGGKKEEETPNHAAEAMPDGPGMTAASGKLYQFRHPVRLFWPKSKCYDYLYQEAEALLKNFPIQATISFYEDSDSEDEIEDLTCEN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
10	Phosphorylation	NAGGAEGTESGAAAC CCCCCCCCCCCHHHH	20.62	-
66	Phosphorylation	MPDGPGMTAASGKLY CCCCCCCCCCCCEEE	25.61	-
73	Phosphorylation	TAASGKLYQFRHPVR CCCCCEEEEECCCEE	14.75	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RIPP2_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RIPP2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RIPP2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KASH5_HUMAN	CCDC155	physical	25416956
SYNE4_HUMAN	SYNE4	physical	25416956
TLE4_HUMAN	TLE4	physical	28514442
TLE2_HUMAN	TLE2	physical	28514442
AES_HUMAN	AES	physical	28514442
TLE3_HUMAN	TLE3	physical	28514442
TLE1_HUMAN	TLE1	physical	28514442
TRIP6_HUMAN	TRIP6	physical	28514442
UBP4_HUMAN	USP4	physical	28514442
RBM23_HUMAN	RBM23	physical	28514442
FERM2_HUMAN	FERMT2	physical	28514442
EXOG_HUMAN	EXOG	physical	28514442

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RIPP2_HUMAN

Related Literatures of Post-Translational Modification