| UniProt ID | RFPL3_HUMAN | |
|---|---|---|
| UniProt AC | O75679 | |
| Protein Name | Ret finger protein-like 3 | |
| Gene Name | RFPL3 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 317 | |
| Subcellular Localization | Cytoplasm . Nucleus . A higher concentration of RFPL3 is observed in the cytoplasm compared to the nucleus. | |
| Protein Description | (Microbial infection) Stimulates the activity of Human Immunodeficiency Virus 1/HIV-1 pre-integration complex.. | |
| Protein Sequence | MKRLSLVTTNRLSPQGNFLPLCTFPLAVDMAALFQEASSCPVCSDYLEKPMSLECGCTVCLKCINSLQKEPHGEDLLCCCCSMVSQRNKIRPNRQLERLVSHIKELEPKLKKILQMNPRMRKFQVDMTLDADTANNFLLISDDLRSVRSGLITQNRQDLAERFDVSVCILGSPRFTCGRHYWEVDVGTSTEWDLGVCRESVHCKGKIQLTTELGFWTVSLRDGSRLSASTVPLTFLLVDRKLQRVGIFLDMGMQNVSFFDAESGSHVYTFRSVSAEEPLRPFLAPSIPPNGDQGVLSICPLMNSGTTDAPVRPGEAK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 5 | Phosphorylation | ---MKRLSLVTTNRL ---CCCEEEEECCCC | 25.48 | 22673903 | |
| 13 | Phosphorylation | LVTTNRLSPQGNFLP EEECCCCCCCCCCCC | 16.37 | 24043423 | |
| 23 | Phosphorylation | GNFLPLCTFPLAVDM CCCCCCCCCCHHHHH | 35.65 | 24043423 | |
| 38 | Phosphorylation | AALFQEASSCPVCSD HHHHHHHHCCCCCHH | 31.55 | 24043423 | |
| 39 | Phosphorylation | ALFQEASSCPVCSDY HHHHHHHCCCCCHHH | 29.50 | 24043423 | |
| 44 | Phosphorylation | ASSCPVCSDYLEKPM HHCCCCCHHHHCCCC | 29.53 | 24043423 | |
| 46 | Phosphorylation | SCPVCSDYLEKPMSL CCCCCHHHHCCCCCC | 10.64 | 24043423 | |
| 153 | Phosphorylation | SVRSGLITQNRQDLA HHHHCCCCCCHHHHH | 25.49 | 28634120 | |
| 172 | Phosphorylation | VSVCILGSPRFTCGR EEEEEECCCCCCCCC | 14.95 | 20562096 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RFPL3_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RFPL3_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RFPL3_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| LNX1_HUMAN | LNX1 | physical | 25416956 | |
| TLK2_HUMAN | TLK2 | physical | 26186194 | |
| DAB2P_HUMAN | DAB2IP | physical | 26186194 | |
| ASND1_HUMAN | ASNSD1 | physical | 26186194 | |
| RFPL1_HUMAN | RFPL1 | physical | 26186194 | |
| RFPL2_HUMAN | RFPL2 | physical | 26186194 | |
| CBP_HUMAN | CREBBP | physical | 26318425 | |
| RFPL1_HUMAN | RFPL1 | physical | 28514442 | |
| RFPL2_HUMAN | RFPL2 | physical | 28514442 | |
| ASND1_HUMAN | ASNSD1 | physical | 28514442 | |
| DAB2P_HUMAN | DAB2IP | physical | 28514442 | |
| TLK2_HUMAN | TLK2 | physical | 28514442 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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