dbPTM

PUP22_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PUP22_ARATH
UniProt AC	Q8RY74
Protein Name	Probable purine permease 22
Gene Name	PUP22
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	377
Subcellular Localization	Membrane Multi-pass membrane protein .
Protein Description
Protein Sequence	MGISQVHYCNGDQNLEANLLDHEETESFSVPQTKNCKRWLRVSIYAIFVIFCQPLATVLGRLYYENGGKSTYVVTLLQLIGFPVLILFRFFSRIRQPKSTDTNFSQSPSFTTLASVYLCTGLLVSAYAYLSAVGLLYLPVSTFSLILASQLAFTAFFSYFLNSQKFTPLIVNSLFLLTVSSALLVVNTDSENTTNVSRVQYVIGFICTIGASAGIGLVLSLIQLLFRKVFTKHTSSAVLDLANYQSLVATCVVLIGLFASGEWRTLPSEMRNYKLGKVSYILTLASAAIFWQVYTVGCVGLIFESSSVFSNSITAVGLPIVPVVAVIVFHDKMDASKIFSIILAIWGFLSFVYQHYLDEKKLKTCQTKPVEEETQTL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
201	Phosphorylation	TNVSRVQYVIGFICT CCCCHHHHHHHHHHH	38.70	19880383
220	Phosphorylation	AGIGLVLSLIQLLFR HHHHHHHHHHHHHHH	10.59	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PUP22_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PUP22_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PUP22_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NAC89_ARATH	NAC089	physical	21798944
GDU2_ARATH	GDU2	physical	22737156
CDPK1_ARATH	CPK1	physical	22737156
GCL1_ARATH	GCL1	physical	22737156
ERDL4_ARATH	AT1G19450	physical	22737156
MLO4_ARATH	MLO4	physical	22737156
UBC34_ARATH	UBC34	physical	24833385
CNIH1_ARATH	AT3G12180	physical	24833385
CP21D_ARATH	AT3G66654	physical	24833385
RHA1A_ARATH	RHA1A	physical	24833385
CRK40_ARATH	CRK40	physical	24833385
WAK3_ARATH	WAK3	physical	24833385
BETL2_ARATH	AT1G29060	physical	24833385
VAP21_ARATH	AT5G47180	physical	24833385

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PUP22_ARATH

Related Literatures of Post-Translational Modification