PSG3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PSG3_HUMAN
• UniProt AC: Q16557
• Protein Name: Pregnancy-specific beta-1-glycoprotein 3
• Gene Name: PSG3
• Organism: Homo sapiens (Human).
• Sequence Length: 428
• Subcellular Localization: Secreted .
• Protein Sequence: MGPLSAPPCTQRITWKGLLLTALLLNFWNLPTTAQVTIEAEPTKVSKGKDVLLLVHNLPQNLAGYIWYKGQMKDLYHYITSYVVDGQIIIYGPAYSGRETVYSNASLLIQNVTREDAGSYTLHIVKRGDGTRGETGHFTFTLYLETPKPSISSSNLYPREDMEAVSLTCDPETPDASYLWWMNGQSLPMTHSLQLSKNKRTLFLFGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLPKPYITINNLNPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIQDRYGGIRSYPVTLNVLYGPDLPRIYPSFTYYHSGENLYLSCFADSNPPAEYSWTINGKFQLSGQKLFIPQITTKHSGLYACSVRNSATGMESSKSMTVKVSAPSGTGHLPGLNPL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MGPLSAPPCTQR ---CCCCCCCCCCCC	41.69	24043423
10	Phosphorylation	PLSAPPCTQRITWKG CCCCCCCCCCCCHHH	27.02	24043423
100	Phosphorylation	PAYSGRETVYSNASL CCCCCCCHHHCCCEE	24.31	-
104	N-linked_Glycosylation	GRETVYSNASLLIQN CCCHHHCCCEEEEEC	18.83	UniProtKB CARBOHYD
111	N-linked_Glycosylation	NASLLIQNVTREDAG CCEEEEECCCHHHCC	30.08	UniProtKB CARBOHYD
135	Phosphorylation	GDGTRGETGHFTFTL CCCCCCCCCEEEEEE	38.49	24719451
228	Phosphorylation	NPVSASRSDPVTLNL CCCCCCCCCCEEEEC	43.71	24888630
268	N-linked_Glycosylation	TCEPKSENYTYIWWL EECCCCCCEEEEEEE	41.35	UniProtKB CARBOHYD
271	Phosphorylation	PKSENYTYIWWLNGQ CCCCCEEEEEEECCC	5.56	-
279	Phosphorylation	IWWLNGQSLPVSPRV EEEECCCCCCCCCCC	35.72	-
283	Phosphorylation	NGQSLPVSPRVKRPI CCCCCCCCCCCCCCC	12.68	-
301	Phosphorylation	ILILPSVTRNETGPY EEEECCCCCCCCCCE	31.92	24719451
303	N-linked_Glycosylation	ILPSVTRNETGPYQC EECCCCCCCCCCEEE	41.64	UniProtKB CARBOHYD
322	Phosphorylation	RYGGIRSYPVTLNVL CCCCCCEEEEEEEEE	7.59	23663014
330	Phosphorylation	PVTLNVLYGPDLPRI EEEEEEEECCCCCCC	23.48	-
392	Phosphorylation	TTKHSGLYACSVRNS EECCCCEEEEEEECC	14.75	20873877
399	Phosphorylation	YACSVRNSATGMESS EEEEEECCCCCCCCC	19.35	-
401	Phosphorylation	CSVRNSATGMESSKS EEEECCCCCCCCCCE	36.56	-
405	Phosphorylation	NSATGMESSKSMTVK CCCCCCCCCCEEEEE	33.89	-
406	Phosphorylation	SATGMESSKSMTVKV CCCCCCCCCEEEEEE	18.55	-
410	Phosphorylation	MESSKSMTVKVSAPS CCCCCEEEEEEECCC	25.02	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PSG3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PSG3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PSG3_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MEGF8_HUMAN	MEGF8	physical	26186194
PSG9_HUMAN	PSG9	physical	26186194
PSG1_HUMAN	PSG1	physical	26186194
FBLN1_HUMAN	FBLN1	physical	26186194
ANR46_HUMAN	ANKRD46	physical	26186194
PSG1_HUMAN	PSG1	physical	28514442
PSG9_HUMAN	PSG9	physical	28514442
ANR46_HUMAN	ANKRD46	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.