dbPTM

PRI2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PRI2_SCHPO
UniProt AC	O74761
Protein Name	DNA primase large subunit
Gene Name	pri2
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	459
Subcellular Localization	Nucleus .
Protein Description	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication..
Protein Sequence	MFRTTKSRVVEKNQNFSSASFESLSYPTRLNFYKKPPVSEISIEEFETWAIDRLVVLGEIESAMLRNKTKNELNGIIKKILDKRLPMSSNMARTVKGNSLDEERRKDHYSHFILRLAFSRSDELRIRFLRAESTLFRFRFVNEETRERQAFIDSLDFQWESVSQEEKDVFYEKLQASSQRNIENESFFKVPFFKVPDLVERRAVFVHKGYAYVPFSEQVSLVVEEFEENLKKALESTAKSLPRLDEDDRLLPILNHLSKGFVAPESSIVAPKSGAITAGQVDSFVSHFPLCAKHLHEVLKRDKHLRHFGRLQYGLFLKDIGLSVDEALVFWRKSFTNVTEDKFNKEYRYNIRHTYGLEGNRKNYKGYNCQQILTGPQLGPGDAHGCPYRTYSVNNLVSALASMGIAPDSAGCREVVEAVKARHYHIACTRVFELTHPNVGSLEESIHHPLQYFQLSLES

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of PRI2_SCHPO !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PRI2_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PRI2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PRI2_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DPOA2_SCHPO	spb70	genetic	15314153
RAD3_SCHPO	rad3	genetic	11027257
RAD26_SCHPO	rad26	genetic	11027257
HUS1_SCHPO	hus1	genetic	11027257
RAD1_SCHPO	rad1	genetic	11027257
RAD9_SCHPO	rad9	genetic	11027257
RAD17_SCHPO	rad17	genetic	11027257
CDS1_SCHPO	cds1	genetic	11027257
DPOA2_SCHPO	spb70	physical	15314153
PRI2_SCHPO	spp2	physical	26771498

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PRI2_SCHPO

Related Literatures of Post-Translational Modification